Journal
NANOMATERIALS
Volume 12, Issue 15, Pages -Publisher
MDPI
DOI: 10.3390/nano12152545
Keywords
plasmonic nanostructures; Cu2-xS nanocrystals; mesoporous silica; photothermal properties
Categories
Funding
- Bilateral project CNR-RFBR (Russia)
- Italian PON project TITAN Nanotechnology for cancer immunotherapy [2021-2023 ARS01_00906]
- PON RAMP
- I project ECOTEC [2014-2020 ARS01_00951]
- PON project [CLOSE ARS01_00141]
- Academic Horizon Europe Seeds Project BIOMAD BIOMarkers for Alzheimer's Disease: early diagnosis and therapeutic targets focused on mitochondrial derangement and inflammasome's activation - University of Bari (Italy)
Ask authors/readers for more resources
Plasmonic nanostructures based on Cu2-xS nanocrystals are emerging as valuable alternatives to traditional materials for photothermal studies and treatment. The size, shape and surface chemistry of the Cu2-xS nanocrystals play a crucial role in their efficiency. Coating the Cu2-xS nanocrystals with a hydrophilic mesoporous silica shell enhances their stability and heat transfer, resulting in good photostability and high photothermal efficiency.
Plasmonic nanostructures, featuring near infrared (NIR)-absorption, are rising as efficient nanosystems for in vitro photothermal (PT) studies and in vivo PT treatment of cancer diseases. Among the different materials, new plasmonic nanostructures based on Cu2-xS nanocrystals (NCs) are emerging as valuable alternatives to Au nanorods, nanostars and nanoshells, largely exploited as NIR absorbing nanoheaters. Even though Cu2-xS plasmonic properties are not linked to geometry, the role played by their size, shape and surface chemistry is expected to be fundamental for an efficient PT process. Here, Cu2-xS NCs coated with a hydrophilic mesoporous silica shell (MSS) are synthesized by solution-phase strategies, tuning the core geometry, MSS thickness and texture. Besides their loading capability, the silica shell has been widely reported to provide a more robust plasmonic core protection than organic molecular/polymeric coatings, and improved heat flow from the NC to the environment due to a reduced interfacial thermal resistance and direct electron-phonon coupling through the interface. Systematic structural and morphological analysis of the core-shell nanoparticles and an in-depth thermoplasmonic characterization by using a pump beam 808 nm laser, are carried out. The results suggest that large triangular nanoplates (NPLs) coated by a few tens of nanometers thick MSS, show good photostability under laser light irradiation and provide a temperature increase above 38 degrees C and a 20% PT efficiency upon short irradiation time (60 s) at 6 W/cm(2) power density.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available