4.3 Article

Long-term safety of satralizumab in neuromyelitis optica spectrum disorder (NMOSD) from SAkuraSky and SAkuraStar

Related references

Note: Only part of the references are listed.
Review Clinical Neurology

Recent progress in maintenance treatment of neuromyelitis optica spectrum disorder

Trygve Holmoy et al.

Summary: For NMOSD patients, monoclonal antibodies that deplete B cells or interfere with interleukin 6 signaling have superior efficacy compared to placebo; Rituximab, tocilizumab, and to some extent eculizumab have well-known safety profiles; Rituximab and azathioprine may be safe during pregnancy.

JOURNAL OF NEUROLOGY (2021)

Article Clinical Neurology

Discontinuation of Immunosuppressive Therapy in Patients With Neuromyelitis Optica Spectrum Disorder With Aquaporin-4 Antibodies

Su-Hyun Kim et al.

Summary: Discontinuation of IST in NMOSD patients may lead to an increased risk of relapse, even after 5 years of remission. Caution is advised when considering IST discontinuation, especially in patients who have experienced severe attacks prior to IST.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2021)

Review Immunology

Drug Treatment of Neuromyelitis Optica Spectrum Disorders: Out with the Old, in with the New?

Friederike Held et al.

Summary: Although satralizumab, eculizumab, and inebilizumab have shown breakthrough short-term efficacy, important questions remain regarding their future use in NMOSD treatment. There is a lack of head-to-head comparison data and the long-term safety and efficacy of these new drugs are still pending. Additionally, the effectiveness of these biologics in AQP4-Ab negative NMOSD patients and in non-responders to conventional immunotherapies is still unknown. Factors such as comorbidities, affordability, and market availability may influence treatment decisions in the near future. While these new drugs are promising, they are not yet poised to completely replace established off-label drugs for NMOSD. The treatment algorithms for NMOSD are still in the process of revision.

IMMUNOTARGETS AND THERAPY (2021)

Article Multidisciplinary Sciences

Transcriptomics and proteomics reveal a cooperation between interferon and T-helper 17 cells in neuromyelitis optica

Agnieshka M. Agasing et al.

NATURE COMMUNICATIONS (2020)

Article Medicine, General & Internal

Neuromyelitis optica

Sven Jarius et al.

NATURE REVIEWS DISEASE PRIMERS (2020)

Review Clinical Neurology

Interleukin-6 in neuromyelitis optica spectrum disorder pathophysiology

Kazuo Fujihara et al.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2020)

Review Clinical Neurology

Review of approved NMO therapies based on mechanism of action, efficacy and long-term effects

Staley A. Brod

MULTIPLE SCLEROSIS AND RELATED DISORDERS (2020)

Article Medicine, General & Internal

Eculizumab in Aquaporin-4-Positive Neuromyelitis Optica Spectrum Disorder

S. J. Pittock et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Review Clinical Neurology

Novel emerging treatments for NMOSD

Krzysztof Selmaj et al.

NEUROLOGIA I NEUROCHIRURGIA POLSKA (2019)

Article Medicine, General & Internal

Trial of Satralizumab in Neuromyelitis Optica Spectrum Disorder

Takashi Yamamura et al.

NEW ENGLAND JOURNAL OF MEDICINE (2019)

Article Rheumatology

Tocilizumab reduces complement C3 and C4 serum levels in rheumatoid arthritis patients

Ciro Romano et al.

CLINICAL RHEUMATOLOGY (2018)

Review Clinical Neurology

Diagnosis and Treatment of NMO Spectrum Disorder and MOG-Encephalomyelitis

Nadja Borisow et al.

FRONTIERS IN NEUROLOGY (2018)

Review Clinical Neurology

Neurodegeneration in multiple sclerosis and neuromyelitis optica

Izumi Kawachi et al.

JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY (2017)

Article Clinical Neurology

Effects of neuromyelitis optica-IgG at the blood-brain barrier in vitro

Yukio Takeshita et al.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2017)

Review Clinical Neurology

Treatment of Neuromyelitis Optica Spectrum Disorder: Acute, Preventive, and Symptomatic

Remi A. Kessler et al.

CURRENT TREATMENT OPTIONS IN NEUROLOGY (2016)

Review Clinical Neurology

Present and Future Therapies in Neuromyelitis Optica Spectrum Disorders

Ingo Kleiter et al.

NEUROTHERAPEUTICS (2016)

Review Neurosciences

Th17 cells in neuromyelitis optica spectrum disorder: a review

Jie Lin et al.

INTERNATIONAL JOURNAL OF NEUROSCIENCE (2016)

Article Clinical Neurology

Neuromyelitis optica spectrum disorders Comparison according to the phenotype and serostatus

Maria Sepulveda et al.

NEUROLOGY-NEUROIMMUNOLOGY & NEUROINFLAMMATION (2016)

Review Clinical Neurology

The Treatment of Neuromyelitis Optica

Markus C. Kowarik et al.

JOURNAL OF NEURO-OPHTHALMOLOGY (2014)

Review Clinical Neurology

Treatment of neuromyelitis optica: state-of-the-art and emerging therapies

Marios C. Papadopoulos et al.

NATURE REVIEWS NEUROLOGY (2014)

Review Neurosciences

Neuromyelitis Optica: An Antibody-Mediated Disorder of the Central Nervous System

Jiwon Oh et al.

NEUROLOGY RESEARCH INTERNATIONAL (2012)

Article Multidisciplinary Sciences

Interleukin 6 signaling promotes anti-aquaporin 4 autoantibody production from plasmablasts in neuromyelitis optica

Norio Chihara et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)

Review Immunology

IL-6: Regulator of Treg/Th17 balance

Akihiro Kimura et al.

EUROPEAN JOURNAL OF IMMUNOLOGY (2010)

Article Clinical Neurology

Cytokine and chemokine profiles in neuromyelitis optica: significance of interleukin-6

Akiyuki Uzawa et al.

MULTIPLE SCLEROSIS JOURNAL (2010)

Review Clinical Neurology

The spectrum of neuromyelitis optica

Dean M. Wingerchuk et al.

LANCET NEUROLOGY (2007)

Article Clinical Neurology

Revised diagnostic criteria for neuromyelitis optica

D. M. Wingerchuk et al.

NEUROLOGY (2006)