4.7 Article

Efficacy and Safety of Bevacizumab Biosimilars Compared With Reference Biologics in Advanced Non-small Cell Lung Cancer or Metastatic Colorectal Cancer Patients: A Network Meta-Analysis

Related references

Note: Only part of the references are listed.
Editorial Material Health Care Sciences & Services

How do biosimilars sustain value, affordability, and access to oncology care?

Steven Simoens

EXPERT REVIEW OF PHARMACOECONOMICS & OUTCOMES RESEARCH (2021)

Article Pharmacology & Pharmacy

Network meta-analysis of infliximab biosimilars for the treatment of rheumatoid arthritis

Conor Hanrahan et al.

Summary: This study assessed the efficacy and safety of infliximab biosimilars in treating patients with RA, finding no significant differences in ACR20 response rates and safety profiles among various infliximab biosimilars and the reference product. Factors such as cost may play a role in decision-making for treatment selection.

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2021)

Article Oncology

Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries

Hyuna Sung et al.

Summary: The global cancer burden in 2020 saw an estimated 19.3 million new cancer cases and almost 10.0 million cancer deaths. Female breast cancer surpassed lung cancer as the most commonly diagnosed cancer, while lung cancer remained the leading cause of cancer death. These trends are expected to rise in 2040, with transitioning countries experiencing a larger increase compared to transitioned countries due to demographic changes and risk factors associated with globalization and a growing economy. Efforts to improve cancer prevention measures and provision of cancer care in transitioning countries will be crucial for global cancer control.

CA-A CANCER JOURNAL FOR CLINICIANS (2021)

Article Oncology

Efficacy, Safety and Immunogenicity of MB02 (Bevacizumab Biosimilar) versus Reference Bevacizumab in Advanced Non-Small Cell Lung Cancer: A Randomized, Double-Blind, Phase III Study (STELLA)

Dmytro Trukhin et al.

Summary: The study confirmed clinical similarity between MB02 and EU-bevacizumab in treating advanced non-squamous non-small cell lung cancer, with comparable efficacy, safety, and immunogenicity profiles.

BIODRUGS (2021)

Article Oncology

Efficacy and Safety of Bevacizumab Biosimilar FKB238 Versus Originator Bevacizumab: Results from AVANA, a Phase III Trial in Patients with Non-Squamous Non-Small-Cell Lung Cancer (non-sq-NSCLC)

Konstantinos Syrigos et al.

Summary: The study revealed that FKB238 and bevacizumab demonstrated similar efficacy and safety profiles in patients with advanced/recurrent non-squamous non-small-cell lung cancer.

BIODRUGS (2021)

Article Oncology

Efficacy, Safety, and Immunogenicity of HLX04 Versus Reference Bevacizumab in Combination with XELOX or mFOLFOX6 as First-Line Treatment for Metastatic Colorectal Cancer: Results of a Randomized, Double-Blind Phase III Study

Shukui Qin et al.

Summary: HLX04, a potential biosimilar to bevacizumab, demonstrated equivalent efficacy, safety, and immunogenicity profiles compared to reference bevacizumab in treating patients with recurrent/metastatic CRC. This supports the development of HLX04 as an alternative treatment option for patients.

BIODRUGS (2021)

Review Oncology

Progress in oncology biosimilars till 2020: Scrutinizing comparative studies of biosimilar monoclonal antibodies

Aqsa Safdar et al.

Summary: The introduction of biosimilars has the potential to reduce the rising healthcare costs associated with cancer treatment, but strict regulatory requirements, challenges in selection and development, and the need for education among healthcare professionals remain key areas of focus. Successful comparative studies have shown biosimilarity with monoclonal antibodies, highlighting the economic impact and savings that can be achieved with biosimilars.

JOURNAL OF ONCOLOGY PHARMACY PRACTICE (2021)

Article Oncology

Bevacizumab biosimilar LY01008 compared with bevacizumab (Avastin) as first-line treatment for Chinese patients with unresectable, metastatic, or recurrent non-squamous non-small-cell lung cancer: A multicenter, randomized, double-blinded, phase III trial

Yuankai Shi et al.

Summary: LY01008 and Avastin demonstrated similar efficacy and safety in Chinese patients with advanced or recurrent non-squamous NSCLC, with no significant differences observed between the two treatments.

CANCER COMMUNICATIONS (2021)

Article Oncology

Safety and efficacy of bevacizumab biosimilar in recurrent/progressive glioblastoma

Gunjesh Kumar et al.

Summary: In patients with recurrent/progressive glioblastoma, both innovator and biosimilar bevacizumab showed similar overall survival and progression-free survival, with comparable adverse events and safety profiles between the two groups.

ECANCERMEDICALSCIENCE (2021)

Article Oncology

Cancer statistics for adolescents and young adults, 2020

Kimberly D. Miller et al.

CA-A CANCER JOURNAL FOR CLINICIANS (2020)

Article Computer Science, Interdisciplinary Applications

Bayesian Random-Effects Meta-Analysis Using the bayesmeta R Package

Christian Roever

JOURNAL OF STATISTICAL SOFTWARE (2020)

Article Health Care Sciences & Services

GRADE approach to rate the certainty from a network meta-analysis: addressing incoherence

Romina Brignardello-Petersen et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2019)

Article Health Care Sciences & Services

Advances in the GRADE approach to rate the certainty in estimates from a network meta-analysis

Romina Brignardello-Petersen et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2018)

Editorial Material Medicine, General & Internal

Biosimilars: Review of current applications, obstacles, and their future in medicine

Flyn Kaida-Yip et al.

WORLD JOURNAL OF CLINICAL CASES (2018)

Review Pharmacology & Pharmacy

Current Status of Biosimilars in Oncology

Luis H. Camacho

DRUGS (2017)

Article Health Care Sciences & Services

A Bayesian network meta-analysis for binary outcome: how to do it

Teresa Greco et al.

STATISTICAL METHODS IN MEDICAL RESEARCH (2016)

Review Dermatology

Biosimilars: a systematic review of published and ongoing clinical trials of antipsoriatics in chronic inflammatory diseases

Alexander Nast et al.

JOURNAL DER DEUTSCHEN DERMATOLOGISCHEN GESELLSCHAFT (2015)

Article Medicine, General & Internal

A GRADE Working Group approach for rating the quality of treatment effect estimates from network meta-analysis

Milo A. Puhan et al.

BMJ-BRITISH MEDICAL JOURNAL (2014)

Article Medicine, General & Internal

Conceptual and Technical Challenges in Network Meta-analysis

Andrea Cipriani et al.

ANNALS OF INTERNAL MEDICINE (2013)

Article Health Care Sciences & Services

Graphical methods and numerical summaries for presenting results from multiple-treatment meta-analysis: an overview and tutorial

Georgia Salanti et al.

JOURNAL OF CLINICAL EPIDEMIOLOGY (2011)

Article Mathematical & Computational Biology

A basic introduction to fixed-effect and random-effects models for meta-analysis

Michael Borenstein et al.

RESEARCH SYNTHESIS METHODS (2010)

Editorial Material Medicine, General & Internal

GRADE:: an emerging consensus on rating quality of evidence and strength of recommendations

Gordon H. Guyatt et al.

BRITISH MEDICAL JOURNAL (2008)