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Dementia and mortality in persons with Down's syndrome
A. Coppus et al.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH (2006)
Mitochondrial dysfunction and tau hyperphosphorylation in Ts1Cje, a mouse model for Down syndrome
Ebrahim Abdul Shukkur et al.
HUMAN MOLECULAR GENETICS (2006)
Increased App expression in a mouse model of Down's syndrome disrupts NGF transport and causes cholinergic neuron degeneration
Ahmad Salehi et al.
NEURON (2006)
Choline acetyltransferase activity at different ages in brain of Ts65Dn mice, an animal model for Down's syndrome and related neurodegenerative diseases
A Contestabile et al.
JOURNAL OF NEUROCHEMISTRY (2006)
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
A Rovelet-Lecrux et al.
NATURE GENETICS (2006)
An aneuploid mouse strain carrying human chromosome 21 with Down syndrome phenotypes
A O'Doherty et al.
SCIENCE (2005)
Abnormal APP, cholinergic and cognitive function in Ts65Dn Down's model mice
HY Seo et al.
EXPERIMENTAL NEUROLOGY (2005)
Identification and characterization of a new Down syndrome model, Ts[Rb(12.1716)]2Cje, resulting from a spontaneous Robertsonian fusion between T(1716)65Dn and mouse Chromosome 12
AJ Villar et al.
MAMMALIAN GENOME (2005)
Chronic LPS exposure produces changes in intrinsic membrane properties and a sustained IL-beta-dependent increase in GABAergic inhibition in hippocampal CA1 pyramidal neurons
IC Hellstrom et al.
HIPPOCAMPUS (2005)
Behavioral and neurobiological markers of Alzheimer's disease in Ts65Dn mice: effects of estrogen
CL Hunter et al.
NEUROBIOLOGY OF AGING (2004)
Minocycline prevents cholinergic loss in a mouse model of Down's syndrome
CL Hunter et al.
ANNALS OF NEUROLOGY (2004)
Cancers and immune related diseases associated with Down's syndrome: a record linkage study
MJ Goldacre et al.
ARCHIVES OF DISEASE IN CHILDHOOD (2004)
Onset of dementia is associated with age at menopause in women with Down's syndrome
N Schupf et al.
ANNALS OF NEUROLOGY (2003)
Characteristic developmental expression of amyloid β40, 42 and 43 in patients with Down syndrome
A Hirayama et al.
BRAIN & DEVELOPMENT (2003)
Frontal cortex BDNF levels correlate with working memory in an animal model of Down syndrome
HA Bimonte-Nelson et al.
BEHAVIOURAL BRAIN RESEARCH (2003)
Behavioral comparison of 4 and 6 month-old Ts65Dn mice: Age-related impairments in working and reference memory
CL Hunter et al.
BEHAVIOURAL BRAIN RESEARCH (2003)
Estrogen restores cognition and cholinergic phenotype in an animal model of Down syndrome
ACE Granholm et al.
PHYSIOLOGY & BEHAVIOR (2002)
Cued recall in early-stage dementia in adults with Down's syndrome
DA Devenny et al.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH (2002)
Intraneuronal Aβ42 accumulation in Down syndrome brain
C Mori et al.
AMYLOID-JOURNAL OF PROTEIN FOLDING DISORDERS (2002)
Characterization of two novel nuclear BTB/POZ domain zinc finger isoforms - Association with differentiation of hippocampal neurons, cerebellar granule cells, and macroglia
C Mitchelmore et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Changes in explicit memory associated with early dementia in adults with Down's syndrome
SJ Krinsky-McHale et al.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH (2002)
Neurological changes and emotional functioning in adults with Down Syndrome
LD Nelson et al.
JOURNAL OF INTELLECTUAL DISABILITY RESEARCH (2001)
Failed retrograde transport of NGF in a mouse model of Down's syndrome: Reversal of cholinergic neurodegenerative phenotypes following NGF infusion
JD Cooper et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
Complement association with neurons and β-amyloid deposition in the brains of aged individuals with down syndrome
E Head et al.
NEUROBIOLOGY OF DISEASE (2001)
Nerve growth factor signaling, neuroprotection, and neural repair
MV Sofroniew et al.
ANNUAL REVIEW OF NEUROSCIENCE (2001)
High-level neuronal expression of Aβ1-42 in wild-type human amyloid protein precursor transgenic mice:: Synaptotoxicity without plaque formation
L Mucke et al.
JOURNAL OF NEUROSCIENCE (2000)
APOE ε4 influences the manifestation of Alzheimer's disease in adults with Down's syndrome
S Deb et al.
BRITISH JOURNAL OF PSYCHIATRY (2000)
Temporal accrual of complement proteins in amyloid plaques in Down's syndrome with Alzheimer's disease
SE Stoltzner et al.
AMERICAN JOURNAL OF PATHOLOGY (2000)
Loss of cholinergic phenotype in basal forebrain coincides with cognitive decline in a mouse model of Down's syndrome
ACE Granholm et al.
EXPERIMENTAL NEUROLOGY (2000)