4.7 Review

Recent advances in pain management based on nanoparticle technologies

Related references

Note: Only part of the references are listed.
Review Nanoscience & Nanotechnology

Management of osteoarthritis: From drug molecules to nano/micromedicines

Martina Di Francesco et al.

Summary: With changes in lifestyle and an aging population, osteoarthritis has become a significant medical burden globally. Current understanding and treatment options for the disease are limited. Inflammatory factors and tissue degradation contribute to the progression of osteoarthritis. Nanotechnology may offer opportunities for its treatment.

WILEY INTERDISCIPLINARY REVIEWS-NANOMEDICINE AND NANOBIOTECHNOLOGY (2022)

Article Pharmacology & Pharmacy

Development of local anesthetic drug delivery system by administration of organo-silica nanoformulations under ultrasound stimuli: in vitro and in vivo investigations

Rong-Qin Qi et al.

Summary: The study developed a novel nano scaffold for sustainable distribution and controlled release of local anesthetic drug Ropivacaine, which can be activated by ultrasound for drug release. Results showed that the nanostructure exhibited a more controlled drug release profile. Cell compatibility and animal model studies demonstrated improved neuron cell survival rates and pain relief effects with this nano scaffold.

DRUG DELIVERY (2021)

Review Nanoscience & Nanotechnology

Nanoconstructs as a versatile tool for detection and diagnosis of Alzheimer biomarkers

Divya Gopalan et al.

Summary: This review discusses the advancements in using nanotechnology for early diagnosis of Alzheimer's disease, focusing on the application of nanomaterials and sensors to detect key biomarkers at very low concentrations. Developing efficient diagnostic tools for early detection is crucial for disease-modifying drugs to be effective in the early stages of the disease. Various types of nanomaterials have been utilized for constructing and enhancing the efficiency of nano-sensors for Alzheimer's disease biosensing at an early stage.

NANOTECHNOLOGY (2021)

Review Pharmacology & Pharmacy

Nano-Medicine in the Cardiovascular System

Danielle Pretorius et al.

Summary: Nano-medicines, including nanoparticles, nanocomposites, small molecules, and exosomes, offer promising future therapies for cardiovascular system dysfunction and other organ disorders due to their special physicochemical properties and favorable cellular responses. The success of these nano-medicines in cardiovascular theranostic applications relies on a comprehensive understanding of the intersection between nanomaterials and biomedical fields. Current research in cardiac nano-medicines focuses on exploring the diverse nature of nanomaterials and their applications, while addressing concerns such as cellular responses, toxicity, and cardio-protective and regenerative capabilities.

FRONTIERS IN PHARMACOLOGY (2021)

Article Chemistry, Multidisciplinary

Bioinspired Theranostic Coordination Polymer Nanoparticles for Intranasal Dopamine Replacement in Parkinson's Disease

Javier Garcia-Pardo et al.

Summary: This study demonstrates the synthesis of neuromelanin bioinspired polymeric nanoparticles for encapsulating DA with high loading efficiency. In vitro, the DA-NCPs showed lower toxicity and enhanced uptake by dopaminergic cells compared to free DA. In vivo, nasal administration of DA-NCPs increased striatal DA levels and reduced apomorphine-induced rotations, highlighting the potential of nanostructured DA for DA-replacement therapy.

ACS NANO (2021)

Review Pharmacology & Pharmacy

Nanotherapeutic-directed approaches to analgesia

Liudmila L. Mazaleuskaya et al.

Summary: The ongoing opioid crisis has highlighted the demand for non-steroidal anti-inflammatory drugs (NSAIDs) as nonaddictive analgesics. Encapsulation of NSAIDs using nanotechnology methods has been reported to reduce systemic toxicity and deliver drugs to diseased tissues. Currently, 57 micro- and nanodrugs have been approved by the US FDA, with nanoanalgesics showing superior efficacy or reduced toxicity compared to placebos.

TRENDS IN PHARMACOLOGICAL SCIENCES (2021)

Article Chemistry, Multidisciplinary

Nerve Growth Factor-Targeted Molecular Theranostics Based on Molybdenum Disulfide Nanosheet-Coated Gold Nanorods (MoS2-AuNR) for Osteoarthritis Pain

Man Ting Au et al.

Summary: The study introduced a novel theranostic nanoprobe targeting osteoarthritis pain, utilizing photoacoustic imaging and photothermal therapy to localize and treat the source of pain. The research found that the nanoprobes could accurately target OA knees and effectively alleviate pain and abnormal behavior in a mouse model.

ACS NANO (2021)

Article Pharmacology & Pharmacy

Optimization of Influential Variables in the Development of Buprenorphine and Bupivacaine Loaded Invasome for Dermal Delivery

Soraya Babaie et al.

Summary: This study investigates the effect of incorporating buprenorphine and bupivacaine hydrochlorides into invasome structures, achieving high EE and loading capacity through full factorial experimental design. The results suggest that this nano-carrier system may be effective for improving dermal penetration of hydrophilic drugs.

ADVANCED PHARMACEUTICAL BULLETIN (2021)

Article Nanoscience & Nanotechnology

Development of biofabricated gold nanoparticles for the treatment of alleviated arthritis pain

Hengyuan An et al.

APPLIED NANOSCIENCE (2020)

Review Neurosciences

The Mesolimbic Dopamine System in Chronic Pain and Associated Affective Comorbidities

Randal A. Serafini et al.

BIOLOGICAL PSYCHIATRY (2020)

Review Urology & Nephrology

Intraoperative Intracavernosal Liposomal Bupivacaine (Exparel) Injection Does Not Affect Systemic Hemodynamics

Hisanori Taniguchi et al.

JOURNAL OF SEXUAL MEDICINE (2020)

Article Nanoscience & Nanotechnology

Oxygen Generating Polymeric Nano Fibers That Stimulate Angiogenesis and Show Efficient Wound Healing in a Diabetic Wound Model

Mubashra Zehra et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2020)

Article Biotechnology & Applied Microbiology

Magnetic core-shell nanowires as MRI contrast agents for cell tracking

Aldo Isaac Martinez-Banderas et al.

JOURNAL OF NANOBIOTECHNOLOGY (2020)

Review Nutrition & Dietetics

Magnesium and Pain

Hyun-Jung Shin et al.

NUTRIENTS (2020)

Review Anesthesiology

Basic pharmacology of local anaesthetics

A. Taylor et al.

BJA EDUCATION (2020)

Review Materials Science, Biomaterials

Anti-vascular nano agents: a promising approach for cancer treatment

Dapeng Chen et al.

JOURNAL OF MATERIALS CHEMISTRY B (2020)

Article Biochemistry & Molecular Biology

Towards precision medicine for pain: diagnostic biomarkers and repurposed drugs

A. B. Niculescu et al.

MOLECULAR PSYCHIATRY (2019)

Article Clinical Neurology

Locating the Site of Neuropathic Pain In Vivo Using MMP-12-Targeted Magnetic Nanoparticles

Syeda Fabeha Husain et al.

PAIN RESEARCH & MANAGEMENT (2019)

Article Engineering, Environmental

Highly flexible transparent substrate-free photoanodes using ZnO nanowires on nickel microfibers

Hong Seok Jo et al.

CHEMICAL ENGINEERING JOURNAL (2019)

Article Multidisciplinary Sciences

Polymer-tetrodotoxin conjugates to induce prolonged duration local anesthesia with minimal toxicity

Chao Zhao et al.

NATURE COMMUNICATIONS (2019)

Article Multidisciplinary Sciences

Improved efficacy of naproxen-loaded NLC for temporomandibular joint administration

Viviane A. Guilherme et al.

SCIENTIFIC REPORTS (2019)

Article Materials Science, Multidisciplinary

Antibody conjugated onto surface modified magnetic nanoparticles for separation of HER2+breast cancer cells

Amir Hossein Haghighi et al.

JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS (2019)

Editorial Material Anesthesiology

Spinal Exparel®-an extended duration of preclinical study needed

James C. Eisenach et al.

BRITISH JOURNAL OF ANAESTHESIA (2019)

Review Chemistry, Multidisciplinary

The role of hollow magnetic nanoparticles in drug delivery

Ghodsi Mohammadi Ziarani et al.

RSC ADVANCES (2019)

Review Oncology

Nanomedicine review: clinical developments in liposomal applications

Esteban Beltran-Gracia et al.

CANCER NANOTECHNOLOGY (2019)

Article Neurosciences

A Critical Role for Dopamine D5 Receptors in Pain Chronicity in Male Mice

Salim Megat et al.

JOURNAL OF NEUROSCIENCE (2018)

Review Biotechnology & Applied Microbiology

Micro to nanoneedles: a trend of modernized transepidermal drug delivery system

Pravin Shende et al.

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY (2018)

Review Chemistry, Multidisciplinary

Current progress and challenges of nanoparticle-based therapeutics in pain management

Vanesa Andreu et al.

JOURNAL OF CONTROLLED RELEASE (2018)

Review Geriatrics & Gerontology

A Comprehensive Review of Non-Steroidal Anti-Inflammatory Drug Use in The Elderly

Supakanya Wongrakpanich et al.

AGING AND DISEASE (2018)

Review Nanoscience & Nanotechnology

Metal oxide modified ZnO nanomaterials for biosensor applications

Nirmalya Tripathy et al.

NANO CONVERGENCE (2018)

Article Chemistry, Multidisciplinary

Analgesic Microneedle Patch for Neuropathic Pain Therapy

Xi Xie et al.

ACS NANO (2017)

Article Nanoscience & Nanotechnology

The analgesia efficiency of ultrasmall magnetic iron oxide nanoparticles in mice chronic inflammatory pain model

Ping-Ching Wu et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2017)

Article Nanoscience & Nanotechnology

Single oral dose of cannabinoid derivate loaded PLGA nanocarriers relieves neuropathic pain for eleven days

Esther Berrocoso et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2017)

Review Pharmacology & Pharmacy

Topical Nano and Microemulsions for Skin Delivery'

Christofori M. R. R. Nastiti et al.

PHARMACEUTICS (2017)

Review Materials Science, Ceramics

Zinc oxide nanoparticles: Biological synthesis and biomedical applications

Hamed Mirzaei et al.

CERAMICS INTERNATIONAL (2017)

Review Clinical Neurology

Neuropathic Pain: Central vs. Peripheral Mechanisms

Kathleen Meacham et al.

CURRENT PAIN AND HEADACHE REPORTS (2017)

Article Chemistry, Physical

Nanotextured cupric oxide nanofibers coated with atomic layer deposited ZnO-TiO2 as highly efficient photocathodes

Min-woo Kim et al.

APPLIED CATALYSIS B-ENVIRONMENTAL (2017)

Article Chemistry, Multidisciplinary

Oxaprozin-Loaded Lipid Nanoparticles towards Overcoming NSAIDs Side-Effects

Jose Lopes-de-Araujo et al.

PHARMACEUTICAL RESEARCH (2016)

Article Nanoscience & Nanotechnology

Flexible, Freestanding, and Binder-free SnOx-ZnO/Carbon Nanofiber Composites for Lithium Ion Battery Anodes

Bhavana N. Joshi et al.

ACS APPLIED MATERIALS & INTERFACES (2016)

Article Pharmacology & Pharmacy

Nanostructured lipid carriers as robust systems for topical lidocaine-prilocaine release in dentistry

Ligia N. M. Ribeiro et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2016)

Article Nanoscience & Nanotechnology

Ethyl cellulose nanoparticles as a platform to decrease ulcerogenic potential of piroxicam: formulation and in vitro/in vivo evaluation

Salma E. El-Habashy et al.

INTERNATIONAL JOURNAL OF NANOMEDICINE (2016)

Review Chemistry, Applied

Opioid-based micro and nanoparticulate formulations: alternative approach on pain management

Andre Sao Pedro et al.

JOURNAL OF MICROENCAPSULATION (2016)

Review Clinical Neurology

Pharmacologic Treatment of Pain

Eapen Mathew et al.

SEMINARS IN PEDIATRIC NEUROLOGY (2016)

Review Biochemical Research Methods

Nanobiotechnology and its applications in drug delivery system: a review

Imran Khan et al.

IET NANOBIOTECHNOLOGY (2015)

Article Pharmacology & Pharmacy

Lyophilized sponges loaded with curcumin solid lipid nanoparticles for buccal delivery: Development and characterization

Heba A. Hazzah et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)

Article Pharmacology & Pharmacy

Drug-in-cyclodextrin-in-liposomes: A novel drug delivery system for flurbiprofen

Lina Zhang et al.

INTERNATIONAL JOURNAL OF PHARMACEUTICS (2015)

Article Immunology

In vivo and systems biology studies implicate IL-18 as a central mediator in chronic pain

Kiran Vasudeva et al.

JOURNAL OF NEUROIMMUNOLOGY (2015)

Article Clinical Neurology

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

Nanna B. Finnerup et al.

LANCET NEUROLOGY (2015)

Article Multidisciplinary Sciences

Nanotechnologies for biomedical science and translational medicine

James R. Heath

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Pharmacology & Pharmacy

Effect of styrene maleic acid WIN55,212-2 micelles on neuropathic pain in a rat model

Oliver Linsell et al.

JOURNAL OF DRUG TARGETING (2015)

Article Biochemistry & Molecular Biology

Liposomal lidocaine gel for topical use at the oral mucosa: characterization, in vitro assays and in vivo anesthetic efficacy in humans

Michelle Franz-Montan et al.

JOURNAL OF LIPOSOME RESEARCH (2015)

Article Chemistry, Physical

Electrospun graphene-ZnO nanofiber mats for photocatalysis applications

Seongpil An et al.

APPLIED SURFACE SCIENCE (2014)

Review Pharmacology & Pharmacy

The role of microneedles for drug and vaccine delivery

Helen L. Quinn et al.

EXPERT OPINION ON DRUG DELIVERY (2014)

Article Geriatrics & Gerontology

Associations Between Serum Biomarkers and Pain and Pain-Related Function in Older Adults with Low Back Pain: A Pilot Study

Gwendolyn A. Sowa et al.

JOURNAL OF THE AMERICAN GERIATRICS SOCIETY (2014)

Review Biotechnology & Applied Microbiology

Emerging targets in neuroinflammation-driven chronic pain

Ru-Rong Ji et al.

NATURE REVIEWS DRUG DISCOVERY (2014)

Article Infectious Diseases

Understanding the Etiology and Management of HIV-Associated Peripheral Neuropathy

Kara Stavros et al.

CURRENT HIV/AIDS REPORTS (2014)

Article Biotechnology & Applied Microbiology

Externally addressable hydrogel nanocomposites for biomedical applications

Scott Brice Campbell et al.

CURRENT OPINION IN CHEMICAL ENGINEERING (2014)

Article Gastroenterology & Hepatology

Enhancing the Enhanced Recovery Program in Colorectal Surgery - Use of Extended-Release Epidural Morphine (DepoDur®)

Rajeev Peravali et al.

ANNALS OF COLOPROCTOLOGY (2014)

Review Pharmacology & Pharmacy

Microneedles for intradermal and transdermal drug delivery

Tuan-Mazlelaa Tuan-Mahmood et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2013)

Article Biochemistry & Molecular Biology

Formulation, characterization and permeability study of nano particles of lipo-endomorphin-1 for oral delivery

Sharareh Eskandari et al.

JOURNAL OF LIPOSOME RESEARCH (2013)

Review Oncology

Macrophage plasticity and polarization in tissue repair and remodelling

Alberto Mantovani et al.

JOURNAL OF PATHOLOGY (2013)

Article Materials Science, Ceramics

Synthesis, characterization and study of photocatalytic activity of surface modified ZnO nanoparticles by PEG capping

M. Sudha et al.

JOURNAL OF SOL-GEL SCIENCE AND TECHNOLOGY (2013)

Article Medicine, Research & Experimental

Stealth Liposomes Encapsulating Zoledronic Acid: A New Opportunity To Treat Neuropathic Pain

Michele Caraglia et al.

MOLECULAR PHARMACEUTICS (2013)

Article Nanoscience & Nanotechnology

Poly-(ethylene glycol) modified gelatin nanoparticles for sustained delivery of the anti-inflammatory drug Ibuprofen-Sodium: An in vitro and in vivo analysis

Dhanya Narayanan et al.

NANOMEDICINE-NANOTECHNOLOGY BIOLOGY AND MEDICINE (2013)

Review Pharmacology & Pharmacy

The use of lipid-based nanocarriers for targeted pain therapies

Susan Hua et al.

FRONTIERS IN PHARMACOLOGY (2013)

Review Pharmacology & Pharmacy

Micro and nanosystems for delivering local anesthetics

Eneida de Paula et al.

EXPERT OPINION ON DRUG DELIVERY (2012)

Article Nanoscience & Nanotechnology

Natural Lipid Nanoparticles Containing Nimesulide: Synthesis, Characterization and In Vivo Antiedematogenic and Antinociceptive Activities

Renata P. Raffin et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2012)

Article Biochemistry & Molecular Biology

Effectiveness of submicronized chitosan-coated liposomes in oral absorption of indomethacin

Hikaru Sugihara et al.

JOURNAL OF LIPOSOME RESEARCH (2012)

Article Chemistry, Medicinal

Benzocaine-loaded polymeric nanocapsules: Study of the anesthetic activities

Nathalie Ferreira Silva De Melo et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2012)

Article Oncology

Gold Nanostructures as Photothermal Therapy Agent for Cancer

Jihye Choi et al.

ANTI-CANCER AGENTS IN MEDICINAL CHEMISTRY (2011)

Review Biochemistry & Molecular Biology

Inflammation and wound healing: the role of the macrophage

Timothy J. Koh et al.

EXPERT REVIEWS IN MOLECULAR MEDICINE (2011)

Review Immunology

Macrophages in skin injury and repair

Babak Mahdavian Delavary et al.

IMMUNOBIOLOGY (2011)

Article Nanoscience & Nanotechnology

Eudragit EPO Nanoparticles: Application in Improving Therapeutic Efficacy and Reducing Ulcerogenicity of Meloxicam on Oral Administration

Parag Khachane et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2011)

Article Nanoscience & Nanotechnology

In-Vitro and In-Vivo Study of Indomethacin Loaded Gelatin Nanoparticles

Rakesh Kumar et al.

JOURNAL OF BIOMEDICAL NANOTECHNOLOGY (2011)

Review Chemistry, Multidisciplinary

Critical factors in the release of drugs from sustained release hydrophilic matrices

Cristina Maderuelo et al.

JOURNAL OF CONTROLLED RELEASE (2011)

Article Chemistry, Applied

Preparation and characterization of ibuprofen solid lipid nanoparticles with enhanced solubility

Sriharsha Gupta Potta et al.

JOURNAL OF MICROENCAPSULATION (2011)

Article Neurosciences

Zinc alleviates pain through high-affinity binding to the NMDA receptor NR2A subunit

Chihiro Nozaki et al.

NATURE NEUROSCIENCE (2011)

Review Pharmacology & Pharmacy

Liposome Technology for Industrial Purposes

Andreas Wagner et al.

JOURNAL OF DRUG DELIVERY (2011)

Review Immunology

Protective and pathogenic functions of macrophage subsets

Peter J. Murray et al.

NATURE REVIEWS IMMUNOLOGY (2011)

Article Nutrition & Dietetics

Zinc bioavailability and homeostasis

K. Michael Hambidge et al.

AMERICAN JOURNAL OF CLINICAL NUTRITION (2010)

Editorial Material Pharmacology & Pharmacy

Challenges of medication management in hospitalized patients with Parkinson's disease

Lindy D. Wood et al.

AMERICAN JOURNAL OF HEALTH-SYSTEM PHARMACY (2010)

Article Biophysics

Preparation and physicochemical characterization of naproxen-PLGA nanoparticles

Yousef Javadzadeh et al.

COLLOIDS AND SURFACES B-BIOINTERFACES (2010)

Article Biotechnology & Applied Microbiology

3D-Wound healing model: Influence of morphine and solid lipid nanoparticles

Sarah Kuechler et al.

JOURNAL OF BIOTECHNOLOGY (2010)

Article Pharmacology & Pharmacy

Polymeric alginate nanoparticles containing the local anesthetic bupivacaine

Renato Grillo et al.

JOURNAL OF DRUG TARGETING (2010)

Review Biochemistry & Molecular Biology

Advances in clinical research methodology for pain clinical trials

John T. Farrar

NATURE MEDICINE (2010)

Review Biochemistry & Molecular Biology

Nociceptor sensitization in pain pathogenesis

Michael S. Gold et al.

NATURE MEDICINE (2010)

Article Dentistry, Oral Surgery & Medicine

Liposome-encapsulated ropivacaine for intraoral topical anesthesia

Michelle Franz-Montan et al.

ORAL SURGERY ORAL MEDICINE ORAL PATHOLOGY ORAL RADIOLOGY AND ENDODONTOLOGY (2010)

Article Anesthesiology

Response to Heat Pain Stimulation in Idiopathic Parkinson's Disease

R. Nandhagopal et al.

PAIN MEDICINE (2010)

Article Neurosciences

Neuropathic Pain: A Maladaptive Response of the Nervous System to Damage

Michael Costigan et al.

Annual Review of Neuroscience (2009)

Review Biochemistry & Molecular Biology

Cellular and Molecular Mechanisms of Pain

Allan I. Basbaum et al.

Review Pharmacology & Pharmacy

Magnesium and Anaesthesia

P. M. Soave et al.

CURRENT DRUG TARGETS (2009)

Review Pharmacology & Pharmacy

CGRP receptors in the control of pain and inflammation

Silvia Benemei et al.

CURRENT OPINION IN PHARMACOLOGY (2009)

Article Urology & Nephrology

Clinical Consequences and Management of Hypomagnesemia

Kevin J. Martin et al.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY (2009)

Review Anesthesiology

Efficacy of opioids for chronic pain - A review of the evidence

Jane C. Ballantyne et al.

CLINICAL JOURNAL OF PAIN (2008)

Article Anesthesiology

Effect of microneedle design on pain in human volunteers

Harvinder S. Gill et al.

CLINICAL JOURNAL OF PAIN (2008)

Article Clinical Neurology

Role of central dopamine in pain and analgesia

Patrick B Wood

Expert Review of Neurotherapeutics (2008)

Review Neurosciences

The neuropathic pain triad: Neurons, immune cells and glia

Joachim Scholz et al.

NATURE NEUROSCIENCE (2007)

Review Pharmacology & Pharmacy

CGRP antagonists: unravelling the role of CGRP in migraine

Henri Doods et al.

TRENDS IN PHARMACOLOGICAL SCIENCES (2007)

Article Anesthesiology

Liposome-encapsulated ropivacaine for topical anesthesia of human oral mucosa

Michelle Franz-Montan et al.

ANESTHESIA AND ANALGESIA (2007)

Review Clinical Neurology

EFNS guidelines on pharmacological treatment of neuropathic pain

N. Attal et al.

EUROPEAN JOURNAL OF NEUROLOGY (2006)

Article Neurosciences

Pain following controlled cutaneous insertion of needles with different diameters

Lars Arendt-Nielsen et al.

SOMATOSENSORY AND MOTOR RESEARCH (2006)

Article Dentistry, Oral Surgery & Medicine

Effectiveness of a transmucosal lidocaine delivery system for local anaesthesia during scaling and root planing

DA Perry et al.

JOURNAL OF CLINICAL PERIODONTOLOGY (2005)

Article Multidisciplinary Sciences

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

A Nimmerjahn et al.

SCIENCE (2005)

Article Physics, Applied

Nanowire-based dye-sensitized solar cells

JB Baxter et al.

APPLIED PHYSICS LETTERS (2005)

Review Pharmacology & Pharmacy

Distribution, functionality and gene regulation of folate receptor isoforms: implications in targeted therapy

H Elnakat et al.

ADVANCED DRUG DELIVERY REVIEWS (2004)

Review Pharmacology & Pharmacy

Microneedles for transdermal drug delivery

MR Prausnitz

ADVANCED DRUG DELIVERY REVIEWS (2004)

Article Materials Science, Multidisciplinary

Nanostructures of zinc oxide

Zhong Lin Wang

MATERIALS TODAY (2004)

Article Anesthesiology

Defining neuropathic pain

MM Backonja

ANESTHESIA AND ANALGESIA (2003)

Article Chemistry, Medicinal

Synthesis and evaluation of ketorolac ester prodrugs for transdermal delivery

HJ Doh et al.

JOURNAL OF PHARMACEUTICAL SCIENCES (2003)

Article Pharmacology & Pharmacy

Pharmacokinetics and pharmacodynamics of zoledronic acid in cancer patients with bone metastases

TL Chen et al.

JOURNAL OF CLINICAL PHARMACOLOGY (2002)

Article Dermatology

Topical anesthetics update: EMLA and beyond

PM Friedman et al.

DERMATOLOGIC SURGERY (2001)

Article Pharmacology & Pharmacy

Pathobiology of neuropathic pain

M Zimmermann

EUROPEAN JOURNAL OF PHARMACOLOGY (2001)

Article Anesthesiology

The local anesthetic properties and toxicity of saxitonin homologues for rat sciatic nerve block in vivo

DS Kohane et al.

REGIONAL ANESTHESIA AND PAIN MEDICINE (2000)