Related references
Note: Only part of the references are listed.The role of RNA editing enzyme ADAR1 in human disease
Brian Song et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2022)
Toll-Like Receptor Signaling and Its Role in Cell-Mediated Immunity
Tianhao Duan et al.
FRONTIERS IN IMMUNOLOGY (2022)
The type I interferonopathies: 10 years on
Yanick J. Crow et al.
NATURE REVIEWS IMMUNOLOGY (2022)
Regulation of RIG-I-like receptor-mediated signaling: interaction between host and viral factors
Koji Onomoto et al.
CELLULAR & MOLECULAR IMMUNOLOGY (2021)
Cytoplasmic DNA: sources, sensing, and role in aging and disease
Karl N. Miller et al.
CELL (2021)
Activation of Innate Immunity by Therapeutic Nucleic Acids
Ali Bishani et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2021)
DNA binding to TLR9 expressed by red blood cells promotes innate immune activation and anemia
L. K. Metthew Lam et al.
SCIENCE TRANSLATIONAL MEDICINE (2021)
Epstein Barr Virus and Autoimmune Responses in Systemic Lupus Erythematosus
Neelakshi R. Jog et al.
FRONTIERS IN IMMUNOLOGY (2021)
Evasion of Intracellular DNA Sensing by Human Herpesviruses
Debipreeta Bhowmik et al.
FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY (2021)
Toll-Like Receptors Gene Polymorphisms in Autoimmune Disease
Yingchi Zhang et al.
FRONTIERS IN IMMUNOLOGY (2021)
The MAVS Immune Recognition Pathway in Viral Infection and Sepsis
Arjun Sharma et al.
ANTIOXIDANTS & REDOX SIGNALING (2021)
Polymorphism of toll-like receptor genes and autoimmune endocrine diseases
Kristina A. Dvornikova et al.
AUTOIMMUNITY REVIEWS (2020)
Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation
Jay Luther et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Mechanisms generating cancer genome complexity from a single cell division error
Neil T. Umbreit et al.
SCIENCE (2020)
A defect in COPI-mediated transport of STING causes immune dysregulation in COPA syndrome
Zimu Deng et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
Emerging roles of Toll-like receptor 9 in cardiometabolic disorders
Sachiko Nishimoto et al.
INFLAMMATION AND REGENERATION (2020)
DNase II activated by the mitochondrial apoptotic pathway regulates RIP1-dependent non-apoptotic hepatocyte death via the TLR9/IFN-β signaling pathway
Yoshinobu Saito et al.
CELL DEATH AND DIFFERENTIATION (2019)
Compromised NLRP3 and AIM2 inflammasome function in autoimmune NZB/W F1 mouse macrophages
Sara J. Thygesen et al.
IMMUNOLOGY AND CELL BIOLOGY (2019)
A Balancing Act: MDA5 in Antiviral Immunity and Autoinflammation
Antonio Gregorio Dias Junior et al.
TRENDS IN MICROBIOLOGY (2019)
Bystander activation and autoimmunity
Yovana Pacheco et al.
JOURNAL OF AUTOIMMUNITY (2019)
NLRP3 inflammasome activation drives tau pathology
Christina Ising et al.
NATURE (2019)
Plasma mitochondrial DNA is elevated in obese type 2 diabetes mellitus patients and correlates positively with insulin resistance
Larysa Yuzefovych et al.
PLOS ONE (2019)
Suppression of STING Associated with LKB1 Loss in KRAS-Driven Lung Cancer
Shunsuke Kitapma et al.
CANCER DISCOVERY (2019)
Toll-like receptors 7 and 9 in myasthenia gravis thymus: amplifiers of autoimmunity?
Paola Cavalcante et al.
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES (2018)
Mitochondria, the NLRP3 Inflammasome, and Sirtuins in Type 2 Diabetes: New Therapeutic Targets
Susana Rovira-Llopis et al.
ANTIOXIDANTS & REDOX SIGNALING (2018)
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
Hachung Chung et al.
CELL (2018)
Breaching Self-Tolerance to Alu Duplex RNA Underlies MDA5-Mediated Inflammation
Sadeem Ahmad et al.
CELL (2018)
Type I interferon pathway activation in COPA syndrome
Stefano Volpi et al.
CLINICAL IMMUNOLOGY (2018)
Detection of Microbial Infections Through Innate Immune Sensing of Nucleic Acids
Xiaojun Tan et al.
ANNUAL REVIEW OF MICROBIOLOGY, VOL 72 (2018)
Inhibition of AIM2 inflammasome activation by a novel transcript isoform of IFI16
Pei-Hui Wang et al.
EMBO REPORTS (2018)
Mitochondrial double-stranded RNA triggers antiviral signalling in humans
Ashish Dhir et al.
NATURE (2018)
Nuclear envelope assembly defects link mitotic errors to chromothripsis
Shiwei Liu et al.
NATURE (2018)
New mitochondrial DNA synthesis enables NLRP3 inflammasome activation
Zhenyu Zhong et al.
NATURE (2018)
Damage-Associated Molecular Patterns in Inflammatory Diseases
Jong Seong Roh et al.
IMMUNE NETWORK (2018)
Molecular mimicry and autoimmunity
Manuel Rojas et al.
JOURNAL OF AUTOIMMUNITY (2018)
Design of amidobenzimidazole STING receptor agonists with systemic activity
Joshi M. Ramanjulu et al.
NATURE (2018)
Discrimination of cytosolic self and non-self RNA by RIG-I-like receptors
Charlotte Laessig et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2017)
NLRP3 inflammasome blockade reduces liver inflammation and fibrosis in experimental NASH in mice
Auvro R. Mridha et al.
JOURNAL OF HEPATOLOGY (2017)
Current role of the NLRP3 inflammasome on obesity and insulin resistance: A systematic review
Jakeline Rheinheimer et al.
METABOLISM-CLINICAL AND EXPERIMENTAL (2017)
cGAS surveillance of micronuclei links genome instability to innate immunity
Karen J. Mackenzie et al.
NATURE (2017)
Mitotic progression following DNA damage enables pattern recognition within micronuclei
Shane M. Harding et al.
NATURE (2017)
Cytoplasmic chromatin triggers inflammation in senescence and cancer
Zhixun Dou et al.
NATURE (2017)
Innate immune sensing of cytosolic chromatin fragments through cGAS promotes senescence
Selene Gluck et al.
NATURE CELL BIOLOGY (2017)
Inflammation in gout: mechanisms and therapeutic targets
Alexander K. So et al.
NATURE REVIEWS RHEUMATOLOGY (2017)
cGAS is essential for cellular senescence
Hui Yang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Tumor cell-specific AIM2 regulates growth and invasion of cutaneous squamous cell carcinoma
Mehdi Farshchian et al.
ONCOTARGET (2017)
Antiribonuclease H2 antibodies are an immune biomarker for systemic lupus erythematosus
Kazuhisa Nozawa et al.
AUTOIMMUNITY (2017)
Nucleic acid-sensing TLRs: trafficking and regulation
Olivia Majer et al.
CURRENT OPINION IN IMMUNOLOGY (2017)
Recurrent Loss of STING Signaling in Melanoma Correlates with Susceptibility to Viral Oncolysis
Tianli Xia et al.
CANCER RESEARCH (2016)
The role of the innate immune system in destruction of pancreatic beta cells in NOD mice and humans with type I diabetes
Ningwen Tai et al.
JOURNAL OF AUTOIMMUNITY (2016)
Activation of STING requires palmitoylation at the Golgi
Kojiro Mukai et al.
NATURE COMMUNICATIONS (2016)
Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
Tianli Xia et al.
CELL REPORTS (2016)
Obesity-induced DNA released from adipocytes stimulates chronic adipose tissue inflammation and insulin resistance
Sachiko Nishimoto et al.
SCIENCE ADVANCES (2016)
Discriminating self from non-self in nucleic acid sensing
Martin Schlee et al.
NATURE REVIEWS IMMUNOLOGY (2016)
Mutations in DDX58, which Encodes RIG-I, Cause Atypical Singleton-Merten Syndrome
Mi-Ae Jang et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2015)
Human Lung Cancer-Derived Immunosuppressive Plasmacytoid Dendritic Cells Release IL-1α in an AIM2 Inflammasome-Dependent Manner
Rosalinda Sorrentino et al.
AMERICAN JOURNAL OF PATHOLOGY (2015)
Molecular Mechanisms in Genetically Defined Autoinflammatory Diseases: Disorders of Amplified Danger Signaling
Adriana Almeida de Jesus et al.
ANNUAL REVIEW OF IMMUNOLOGY VOL 33 (2015)
Critical Role for the DNA Sensor AIM2 in Stem Cell Proliferation and Cancer
Si Ming Man et al.
CELL (2015)
Chromothripsis from DNA damage in micronuclei
Cheng-Zhong Zhang et al.
NATURE (2015)
Epigenetic silencing of TH1-type chemokines shapes tumour immunity and immunotherapy
Dongjun Peng et al.
NATURE (2015)
COPA mutations impair ER-Golgi transport and cause hereditary autoimmune-mediated lung disease and arthritis
Levi B. Watkin et al.
NATURE GENETICS (2015)
Inflammasome-independent role of AIM2 in suppressing colon tumorigenesis via DNA-PK and Akt
Justin E. Wilson et al.
NATURE MEDICINE (2015)
Anti-HMGB1 antibody reduces weight gain in mice fed a high-fat diet
V. N. Montes et al.
NUTRITION & DIABETES (2015)
IFIH1 Mutation Causes Systemic Lupus Erythematosus With Selective IgA Deficiency
Lien Van Eyck et al.
ARTHRITIS & RHEUMATOLOGY (2015)
Defective removal of ribonucleotides from DNA promotes systemic autoimmunity
Claudia Guenther et al.
JOURNAL OF CLINICAL INVESTIGATION (2015)
Sex-dependent differential activation of NLRP3 and AIM2 inflammasomes in SLE macrophages
Chin-An Yang et al.
RHEUMATOLOGY (2015)
Translating nucleic acid-sensing pathways into therapies
Tobias Junt et al.
NATURE REVIEWS IMMUNOLOGY (2015)
Autoimmune Disorders Associated with Gain of Function of the Intracellular Sensor MDA5
Masahide Funabiki et al.
IMMUNITY (2014)
Gain-of-function mutations in IFIH1 cause a spectrum of human disease phenotypes associated with upregulated type I interferon signaling
Gillian I. Rice et al.
NATURE GENETICS (2014)
Activated STING in a Vascular and Pulmonary Syndrome
Y. Liu et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Binding-Pocket and Lid-Region Substitutions Render Human STING Sensitive to the Species-Specific Drug DMXAA
Pu Gao et al.
CELL REPORTS (2014)
Catastrophic Nuclear Envelope Collapse in Cancer Cell Micronuclei
Emily M. Hatch et al.
CELL (2013)
Clinical significance of serum mitochondrial DNA in lung cancer
Yu-Lei Hou et al.
CLINICAL BIOCHEMISTRY (2013)
EBV stimulates TLR- and autophagy-dependent pathways and impairs maturation in plasmacytoid dendritic cells: Implications for viral immune escape
Martina Severa et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2013)
Mouse, but not Human STING, Binds and Signals in Response to the Vascular Disrupting Agent 5,6-Dimethylxanthenone-4-Acetic Acid
Joseph Conlon et al.
JOURNAL OF IMMUNOLOGY (2013)
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
Lijun Sun et al.
SCIENCE (2013)
Type I interferonopathies: a novel set of inborn errors of immunity
Yanick J. Crow
YEAR IN HUMAN AND MEDICAL GENETICS: INBORN ERRORS OF IMMUNITY I (2011)
Host type I IFN signals are required for antitumor CD8+ T cell responses through CD8α+ dendritic cells
Mercedes B. Fuertes et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Type I interferon is selectively required by dendritic cells for immune rejection of tumors
Mark S. Diamond et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
Autophagy proteins regulate innate immune responses by inhibiting the release of mitochondrial DNA mediated by the NALP3 inflammasome
Kiichi Nakahira et al.
NATURE IMMUNOLOGY (2011)
Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions
Yvonne Dombrowski et al.
SCIENCE TRANSLATIONAL MEDICINE (2011)
Changes in the pattern of DNA methylation associate with twin discordance in systemic lupus erythematosus
Biola M. Javierre et al.
GENOME RESEARCH (2010)
Horror Autoinflammaticus: The Molecular Pathophysiology of Autoinflammatory Disease
Seth L. Masters et al.
ANNUAL REVIEW OF IMMUNOLOGY (2009)
The role of inflammation in insulitis and β-cell loss in type 1 diabetes
Decio L. Eizirik et al.
NATURE REVIEWS ENDOCRINOLOGY (2009)
Toll-like Receptor and RIG-1-like Receptor Signaling
Taro Kawai et al.
YEAR IN IMMUNOLOGY 2008 (2008)
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
Hiroki Ishikawa et al.
NATURE (2008)
TLR3 deficiency in patients with herpes simplex encephalitis
Shen-Ying Zhang et al.
SCIENCE (2007)
Pattern of interleukin-1β secretion in response to lipopolysaccharide and ATP before and after interleukin-1 blockade in patients with CIAS1 mutations
Marco Gattorno et al.
ARTHRITIS AND RHEUMATISM (2007)
Disease-associated mutations in CIAS1 induce cathepsin B-dependent rapid cell death of human THP-1 monocytic cells
Akihiro Fujisawa et al.
BLOOD (2007)
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
Wen Xue et al.
NATURE (2007)
Regulation of innate antiviral defenses through a shared repressor domain in RIG-I and LGP2
Takeshi Saito et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Toll-like receptor 3 is an essential component of the innate stress response in virus-induced cardiac injury
Hordur S. Hardarson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Recognition of single-stranded RNA viruses by Toll-like receptor 7
JM Lund et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
SS Diebold et al.
SCIENCE (2004)
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
T Wang et al.
NATURE MEDICINE (2004)
Toll-like receptor 9-dependent and -independent dendritic cell activation by chromatin-immunoglobulin G complexes
MW Boulé et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2004)
The antitumour activity of 5,6-dimethylxanthenone-4-acetic acid (DMXAA) in TNF receptor-I knockout mice
L Zhao et al.
BRITISH JOURNAL OF CANCER (2002)
Demethylation of classical satellite 2 and 3 DNA with chromosomal instability in senescent human fibroblasts
T Suzuki et al.
EXPERIMENTAL GERONTOLOGY (2002)
mda-5:: An interferon-inducible putative RNA helicase with double-stranded RNA-dependent ATPase activity and melanoma growth-suppressive properties
DC Kang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
A Toll-like receptor recognizes bacterial DNA
H Hemmi et al.
NATURE (2000)