Journal
ELIFE
Volume 11, Issue -, Pages -Publisher
eLIFE SCIENCES PUBL LTD
DOI: 10.7554/eLife.80699
Keywords
COVID-19; SARS-CoV-2; macrophage polarization; efferocytosis; hyperinflammation; tissue repair; Human
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Macrophages fail to transition into an anti-inflammatory state after engulfing viable SARS-CoV-2 particles, potentially contributing to damaging immune reactions associated with severe COVID-19.
Macrophages absorbing cells infected with viable SARS-CoV-2 particles fail to transition into an anti-inflammatory state, potentially contributing to a damaging immune reaction linked to severe forms of COVID-19.
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