BRAIN Connecting the lines after a stroke

Article Clinical Neurology

Post-stroke outcomes predicted from multivariate lesion-behaviour and lesion network mapping

Mark Bowren et al.

Summary: Predicting chronic post-stroke outcomes is challenging due to individual variability and reliance on clinical heuristics. This study explores the use of lesion-behaviour mapping and structural and functional lesion networks to improve prediction of 12-month cognitive and motor outcomes in stroke patients. The results show that both methods can significantly predict variance in outcomes, with variations in performance for specific deficits.

BRAIN (2022)

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Article Biology

Homotopic contralesional excitation suppresses spontaneous circuit repair and global network reconnections following ischemic stroke

Annie R. Bice et al.

Summary: Understanding circuit-level manipulations that affect brain plasticity can help design targeted interventions for enhancing stroke recovery. Contralateral excitation after stroke can suppress cortical remodeling and transcriptional changes in recovery-related genes, as well as affect functional connectivity. Therefore, careful site selection is important for targeted therapeutic interventions after stroke.

ELIFE (2022)

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Article Neurosciences

Circuit-Specific Plasticity of Callosal Inputs Underlies Cortical Takeover

Emily Petrus et al.

JOURNAL OF NEUROSCIENCE (2020)

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Review Cell Biology

Non-invasive electrical brain stimulation: from acute to late-stage treatment of central nervous system damage

Petra Henrich-Noack et al.

NEURAL REGENERATION RESEARCH (2017)

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Article Multidisciplinary Sciences

Optogenetic neuronal stimulation promotes functional recovery after stroke

Michelle Y. Cheng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)

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Article Neurosciences

Cell Diversity and Connection Specificity between Callosal Projection Neurons in the Frontal Cortex

Takeshi Otsuka et al.

JOURNAL OF NEUROSCIENCE (2011)

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Article Neurosciences

In Vivo Voltage-Sensitive Dye Imaging in Adult Mice Reveals That Somatosensory Maps Lost to Stroke Are Replaced over Weeks by New Structural and Functional Circuits with Prolonged Modes of Activation within Both the Peri-Infarct Zone and Distant Sites

Craig E. Brown et al.

JOURNAL OF NEUROSCIENCE (2009)

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BRAIN Connecting the lines after a stroke

Related references

Post-stroke outcomes predicted from multivariate lesion-behaviour and lesion network mapping

Homotopic contralesional excitation suppresses spontaneous circuit repair and global network reconnections following ischemic stroke

Circuit-Specific Plasticity of Callosal Inputs Underlies Cortical Takeover

Non-invasive electrical brain stimulation: from acute to late-stage treatment of central nervous system damage

Optogenetic neuronal stimulation promotes functional recovery after stroke

Cell Diversity and Connection Specificity between Callosal Projection Neurons in the Frontal Cortex

In Vivo Voltage-Sensitive Dye Imaging in Adult Mice Reveals That Somatosensory Maps Lost to Stroke Are Replaced over Weeks by New Structural and Functional Circuits with Prolonged Modes of Activation within Both the Peri-Infarct Zone and Distant Sites

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