4.8 Article

Calcium sparks enhance the tissue fluidity within epithelial layers and promote apical extrusion of transformed cells

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis

Yukinari Haraoka et al.

Summary: The study demonstrates that oncogenic cells can be eliminated through oncogene-induced senescence, but this behavior can be altered by a p53 mutation, leading to promotion rather than suppression of tumorigenesis. The findings provide important insights into the initial step of tumor formation.

NATURE COMMUNICATIONS (2022)

Article Multidisciplinary Sciences

FBP17-mediated finger-like membrane protrusions in cell competition between normal and RasV12-transformed cells

Tomoko Kamasaki et al.

Summary: Research has found that characteristic finger-like membrane protrusions are projected from both normal and RasV12 cells at their interface, and FBP17 protein accumulates in RasV12 cells and surrounding normal cells, playing a positive role in the formation of these protrusions and the apical elimination of RasV12 cells. It is also shown that cdc42 acts upstream of these processes, indicating that the cdc42/FBP17 pathway is a crucial trigger of cell competition.

ISCIENCE (2021)

Review Oncology

Cell competition and tumorigenesis in the imaginal discs of Drosophila

Gines Morata et al.

SEMINARS IN CANCER BIOLOGY (2020)

Article Biochemistry & Molecular Biology

Calcium Wave Promotes Cell Extrusion

Yasuto Takeuchi et al.

CURRENT BIOLOGY (2020)

Review Genetics & Heredity

Emerging mechanisms of cell competition

Nicholas E. Baker

NATURE REVIEWS GENETICS (2020)

Review Oncology

Outcompeting cancer

Medhavi Vishwakarma et al.

NATURE REVIEWS CANCER (2020)

Review Developmental Biology

y Cell competition: the winners and losers of fitness selection

Sarah Bowling et al.

DEVELOPMENT (2019)

Review Cell Biology

Insights into the quantitative and dynamic aspects of Cell Competition

Covadonga Diaz-Diaz et al.

CURRENT OPINION IN CELL BIOLOGY (2019)

Review Cell Biology

Cell competition in development: information from flies and vertebrates

Esha Madan et al.

CURRENT OPINION IN CELL BIOLOGY (2018)

Article Chemistry, Multidisciplinary

A fluorescent membrane tension probe

Adai Colom et al.

NATURE CHEMISTRY (2018)

Article Cell Biology

Cell competition in mammals - novel homeostatic machinery for embryonic development and cancer prevention

Takeshi Maruyama et al.

CURRENT OPINION IN CELL BIOLOGY (2017)

Article Biophysics

Inference of Internal Stress in a Cell Monolayer

Vincent Nier et al.

BIOPHYSICAL JOURNAL (2016)

Article Biochemistry & Molecular Biology

Tissue Crowding Induces Caspase-Dependent Competition for Space

Romain Levayer et al.

CURRENT BIOLOGY (2016)

Article Multidisciplinary Sciences

Mechanical cell competition kills cells via induction of lethal p53 levels

Laura Wagstaff et al.

NATURE COMMUNICATIONS (2016)

Article Multidisciplinary Sciences

Cell mixing induced by myc is required for competitive tissue invasion and destruction

Romain Levayer et al.

NATURE (2015)

Article Multidisciplinary Sciences

Improved Long-Term Imaging of Embryos with Genetically Encoded α-Bungarotoxin

Ian A. Swinburne et al.

PLOS ONE (2015)

Article Multidisciplinary Sciences

Mechanical stimulation induces formin-dependent assembly of a perinuclear actin rim

Xiaowei Shao et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

Ezrin is a Major Regulator of Membrane Tension in Epithelial Cells

Bastian Rouven Brueckner et al.

SCIENTIFIC REPORTS (2015)

Article Multidisciplinary Sciences

Calcium Spikes in Epithelium: study on Drosophila early embryos

Olga Markova et al.

SCIENTIFIC REPORTS (2015)

Proceedings Paper Materials Science, Multidisciplinary

Viscoelastic effects of silicone gels at the micro- and nanoscale

Kenry et al.

IUTAM SYMPOSIUM ON MECHANICS OF SOFT ACTIVE MATERIALS (2015)

Review Developmental Biology

Cell competition: how to eliminate your neighbours

Marc Amoyel et al.

DEVELOPMENT (2014)

Article Multidisciplinary Sciences

Filamin acts as a key regulator in epithelial defence against transformed cells

Mihoko Kajita et al.

NATURE COMMUNICATIONS (2014)

Article Multidisciplinary Sciences

scikit-image: image processing in Python

Stefan van der Walt et al.

PEERJ (2014)

Article Multidisciplinary Sciences

Ultrasensitive fluorescent proteins for imaging neuronal activity

Tsai-Wen Chen et al.

NATURE (2013)

Article Biotechnology & Applied Microbiology

DNA targeting specificity of RNA-guided Cas9 nucleases

Patrick D. Hsu et al.

NATURE BIOTECHNOLOGY (2013)

Article Multidisciplinary Sciences

Outgrowth of single oncogene-expressing cells from suppressive epithelial environments

Cheuk T. Leung et al.

NATURE (2012)

Article Multidisciplinary Sciences

Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia

George T. Eisenhoffer et al.

NATURE (2012)

Article Multidisciplinary Sciences

Spatial organization of the extracellular matrix regulates cell-cell junction positioning

Qingzong Tseng et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)

Review Cell Biology

Calcium signaling in developing embryos: Focus on the regulation of cell shape changes and collective movements

Olga Markova et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2012)

Article Multidisciplinary Sciences

Calcium flickers steer cell migration

Chaoliang Wei et al.

NATURE (2009)

Article Cell Biology

Characterization of the interface between normal and transformed epithelial cells

Catherine Hogan et al.

NATURE CELL BIOLOGY (2009)

Review Multidisciplinary Sciences

Competitive Interactions Between Cells: Death, Growth, and Geography

Laura A. Johnston

SCIENCE (2009)

Review Mathematics, Applied

l1 Trend Filtering

Seung-Jean Kim et al.

SIAM REVIEW (2009)

Article Biochemical Research Methods

Phase transfer surfactant-aided trypsin digestion for membrane proteome analysis

Takeshi Masuda et al.

JOURNAL OF PROTEOME RESEARCH (2008)

Article Biochemistry & Molecular Biology

Global, in vivo, and site-specific phosphorylation dynamics in signaling networks

Jesper V. Olsen et al.

Article Cell Biology

TRPC1 forms the stretch-activated cation channel in vertebrate cells

R Maroto et al.

NATURE CELL BIOLOGY (2005)

Article Biochemistry & Molecular Biology

Rap1 regulates the formation of E-cadherin-based cell-cell contacts

C Hogan et al.

MOLECULAR AND CELLULAR BIOLOGY (2004)

Article Biotechnology & Applied Microbiology

A high signal-to-noise Ca2+ probe composed of a single green fluorescent protein

J Nakai et al.

NATURE BIOTECHNOLOGY (2001)