4.7 Article

Divergent encoding of active avoidance behavior in corticostriatal and corticolimbic projections

Related references

Note: Only part of the references are listed.
Article Neurosciences

Frontostriatal Projections Regulate Innate Avoidance Behavior

Adrienne C. Loewke et al.

Summary: The dorsomedial prefrontal cortex (dmPFC) plays a key role in controlling defensive behavior through specific top-down projections. The dmPFC-amygdala projection is involved in reflexive fear behavior, while the dmPFC-striatum projection regulates anxious avoidance behavior. These findings provide important insights into the neural mechanisms underlying anxiety disorders.

JOURNAL OF NEUROSCIENCE (2021)

Article Multidisciplinary Sciences

Dynamical prefrontal population coding during defensive behaviours

Daniel Jercog et al.

Summary: The study found that threat representations and avoidance behavior initiation are dynamically encoded in the overall population activity of dmPFC neurons in mice. While dmPFC population activity at stimulus onset encodes sustained threat representations driven by the amygdala, it does not predict action outcome. Transient dmPFC population activity before the initiation of action reliably predicts avoided from non-avoided trials, revealing the dynamic process of information linking threats with defensive actions within prefrontal networks.

NATURE (2021)

Article Multidisciplinary Sciences

ezTrack: An open-source video analysis pipeline for the investigation of animal behavior

Zachary T. Pennington et al.

SCIENTIFIC REPORTS (2019)

Article Biochemistry & Molecular Biology

The Bilateral Prefronto-striatal Pathway Is Necessary for Learning New Goal-Directed Actions

Genevra Hart et al.

CURRENT BIOLOGY (2018)

Article Neurosciences

Prefrontal Corticostriatal Disconnection Blocks the Acquisition of Goal-Directed Action

Genevra Hart et al.

JOURNAL OF NEUROSCIENCE (2018)

Article Multidisciplinary Sciences

Bidirectional coordination of actions and habits by TrkB in mice

Elizabeth G. Pitts et al.

SCIENTIFIC REPORTS (2018)

Article Neurosciences

Multi-dimensional Coding by Basolateral Amygdala Neurons

Pinelopi Kyriazi et al.

NEURON (2018)

Article Neurosciences

Central Amygdala Somatostatin Neurons Gate Passive and Active Defensive Behaviors

Kai Yu et al.

JOURNAL OF NEUROSCIENCE (2016)

Article Multidisciplinary Sciences

Prefrontal neuronal assemblies temporally control fear behaviour

Cyril Dejean et al.

NATURE (2016)

Review Neurosciences

Going and stopping: dichotomies in behavioral control by the prefrontal cortex

Shannon L. Gourley et al.

NATURE NEUROSCIENCE (2016)

Article Biochemistry & Molecular Biology

Intact-Brain Analyses Reveal Distinct Information Carried by SNc Dopamine Subcircuits

Talia N. Lerner et al.

Article Biochemistry & Molecular Biology

A Corticostriatal Path Targeting Striosomes Controls Decision-Making under Conflict

Alexander Friedman et al.

Article Multidisciplinary Sciences

A temporal shift in the circuits mediating retrieval of fear memory

Fabricio H. Do-Monte et al.

NATURE (2015)

Article Multidisciplinary Sciences

Basomedial amygdala mediates top-down control of anxiety and fear

Avishek Adhikari et al.

NATURE (2015)

Review Neurosciences

Neuronal circuits for fear and anxiety

Philip Tovote et al.

NATURE REVIEWS NEUROSCIENCE (2015)

Review Behavioral Sciences

The Role of the Medial Prefrontal Cortex in the Conditioning and Extinction of Fear

Thomas F. Giustino et al.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2015)

Article Neurosciences

Taking Action in the Face of Threat: Neural Synchronization Predicts Adaptive Coping

Katherine A. Collins et al.

JOURNAL OF NEUROSCIENCE (2014)

Article Neurosciences

Neural Structures Mediating Expression and Extinction of Platform-Mediated Avoidance

Christian Bravo-Rivera et al.

JOURNAL OF NEUROSCIENCE (2014)

Article Neurosciences

Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety

Ekaterina Likhtik et al.

NATURE NEUROSCIENCE (2014)

Article Neurosciences

Avoidant symptoms in PTSD predict fear circuit activation during multimodal fear extinction

Rebecca K. Sripada et al.

FRONTIERS IN HUMAN NEUROSCIENCE (2013)

Article Neurosciences

Active Avoidance Learning Requires Prefrontal Suppression of Amygdala-Mediated Defensive Reactions

Justin M. Moscarello et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Neurosciences

Synaptic Encoding of Fear Extinction in mPFC-amygdala Circuits

Jun-Hyeong Cho et al.

NEURON (2013)

Article Multidisciplinary Sciences

Orbitofrontal and striatal circuits dynamically encode the shift between goal-directed and habitual actions

Christina M. Gremel et al.

NATURE COMMUNICATIONS (2013)

Review Physiology

Striatal Mechanisms Underlying Movement, Reinforcement, and Punishment

Alexxai V. Kravitz et al.

PHYSIOLOGY (2012)

Article Behavioral Sciences

Avoiding negative outcomes: tracking the mechanisms of avoidance learning in humans during fear conditioning

Mauricio R. Delgado et al.

FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2009)