4.4 Article

miR-146a-5p negatively regulates the IL-1β-stimulated inflammatory response via downregulation of the IRAK1/TRAF6 signaling pathway in human intestinal epithelial cells

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Summary: This study demonstrated that miR-146a-5p negatively regulates LPS-induced NF Kappa B activation and the NLRP3 inflammasome signaling pathway in HUVECs by modulating TRAF6 and IRAK1 expression, indicating its potential as a therapeutic target for atherosclerosis.

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