Related references
Note: Only part of the references are listed.Nanobodies as allosteric modulators of Parkinson's disease-associated LRRK2
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Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease
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LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6
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Ser1292 Autophosphorylation Is an Indicator of LRRK2 Kinase Activity and Contributes to the Cellular Effects of PD Mutations
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14-3-3 binding to LRRK2 is disrupted by multiple Parkinson's disease-associated mutations and regulates cytoplasmic localization
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BIOCHEMICAL JOURNAL (2010)
Inhibitors of leucine-rich repeat kinase-2 protect against models of Parkinson's disease
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ANNALS OF NEUROLOGY (2008)
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Intramolecular Activation Mechanism of theDictyosteliumLRRK2 Homolog Roco Protein GbpC
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LRRK2 Gly2385Arg mutation and clinical features in a Chinese population with early-onset Parkinson's disease compared to late-onset patients
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The Parkinson's disease-associated protein, leucine-rich repeat kinase 2 (LRRK2), is an authentic GTPase that stimulates kinase activity
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ANNALS OF NEUROLOGY (2006)
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A common missense variant in the LRRK2 gene, Gly2385Arg, associated with Parkinson's disease risk in Taiwan
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The Parkinson disease causing LRRK2 mutation I2020T is associated with increased kinase activity
CJ Gloeckner et al.
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Parkinson's disease-associated mutations in leucine-rich repeat kinase 2 augment kinase activity
AB West et al.
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The G2019S LRRK2 mutation is uncommon in an Asian cohort of Parkinson's disease patients
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Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease
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NEURON (2004)
Mutations in LRRK2 cause autosomal-dominant Parkinsonism with pleomorphic pathology
A Zimprich et al.
NEURON (2004)
Roc, a Ras/GTPase domain in complex proteins
L Bosgraaf et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2003)
A new locus for Parkinson's disease (PARK8) maps to chromosome 12p11.2-q13.1
M Funayama et al.
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Signal transduction - The guanine nucleotide-binding switch in three dimensions
IR Vetter et al.
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