4.6 Article

CCAAT/Enhancer-binding Protein Homologous Protein Promotes ROS-mediated Liver Ischemia and Reperfusion Injury by Inhibiting Mitophagy in Hepatocytes

Related references

Note: Only part of the references are listed.
Article Immunology

Aeromonas hydrophila inhibits autophagy triggering cytosolic translocation of mtDNA which activates the pro-apoptotic caspase-1/IL-1β-nitric oxide axis in headkidney macrophages

Manmohan Kumar et al.

Summary: This study investigates the molecular mechanisms of Aerornonas hydrophila-induced pathogenesis in fish. The findings suggest that the infection leads to ER stress and mitochondrial dysfunction, resulting in the production of mtROS and translocation of mtDNA into the cytosol, which ultimately triggers cell apoptosis.

VIRULENCE (2022)

Article Engineering, Environmental

Endoplasmic reticulum stress manipulates autophagic response that antagonizes polybrominated diphenyl ethers quinone induced cytotoxicity in microglial BV2 cells

Qiushuang Zhu et al.

Summary: The study revealed that the PBDEQ-induced autophagy in microglial BV2 cells may be linked to endoplasmic reticulum stress and cytotoxicity. The findings suggest a potential role of autophagy in regulating cytotoxicity induced by PBDEQ in BV2 cells through pathways like protein kinase R-like ER kinase.

JOURNAL OF HAZARDOUS MATERIALS (2021)

Article Biochemistry & Molecular Biology

Fumarate and oxidative stress synergize to promote stability of C/EBP homologous protein in the adipocyte

Allison M. Manuel et al.

FREE RADICAL BIOLOGY AND MEDICINE (2020)

Article Neurosciences

Deletion of a Neuronal Drp1 Activator Protects against Cerebral Ischemia

Kyle H. Flippo et al.

JOURNAL OF NEUROSCIENCE (2020)

Review Immunology

The essential functions of mitochondrial dynamics in immune cells

Jia-Huan Xie et al.

CELLULAR & MOLECULAR IMMUNOLOGY (2020)

Article Medicine, Research & Experimental

Mitophagy is a protective response against oxidative damage in bone marrow mesenchymal stem cells

Pan Fan et al.

LIFE SCIENCES (2019)

Review Multidisciplinary Sciences

Cellular quality control by the ubiquitin-proteasome system and autophagy

Christian Pohl et al.

SCIENCE (2019)

Article Medicine, Research & Experimental

An alternative mitophagy pathway mediated by Rab9 protects the heart against ischemia

Toshiro Saito et al.

JOURNAL OF CLINICAL INVESTIGATION (2019)

Review Biochemistry & Molecular Biology

The Unfolded Protein Response and Cell Fate Control

Claudio Hetz et al.

MOLECULAR CELL (2018)

Article Multidisciplinary Sciences

Autophagy promotes the survival of dormant breast cancer cells and metastatic tumour recurrence

Laura Vera-Ramirez et al.

NATURE COMMUNICATIONS (2018)

Article Neurosciences

AKAP1 Protects from Cerebral Ischemic Stroke by Inhibiting Drp1-Dependent Mitochondrial Fission

Kyle H. Flippo et al.

JOURNAL OF NEUROSCIENCE (2018)

Article Gastroenterology & Hepatology

Combination of tauroursodeoxycholic acid and N-acetylcysteine exceeds standard treatment for acetaminophen intoxication

Annelies Paridaens et al.

LIVER INTERNATIONAL (2017)

Article Gastroenterology & Hepatology

Hepatocyte-derived macrophage migration inhibitory factor mediates alcohol-induced liver injury in mice and patients

Veronica Marin et al.

JOURNAL OF HEPATOLOGY (2017)

Review Urology & Nephrology

Endoplasmic reticulum stress, the unfolded protein response and autophagy in kidney diseases

Andrey V. Cybulsky

NATURE REVIEWS NEPHROLOGY (2017)

Review Neurosciences

Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms

Jesse S. Kerr et al.

TRENDS IN NEUROSCIENCES (2017)

Review Cardiac & Cardiovascular Systems

Autophagy and Mitophagy in Cardiovascular Disease

Jose Manuel Bravo-San Pedro et al.

CIRCULATION RESEARCH (2017)

Article Pharmacology & Pharmacy

Drp-1, a potential therapeutic target for brain ischaemic stroke

W. Zuo et al.

BRITISH JOURNAL OF PHARMACOLOGY (2016)

Review Biochemistry & Molecular Biology

Endoplasmic Reticulum Stress and Associated ROS

Hafiz Maher Ali Zeeshan et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2016)

Article Cell Biology

BECN1s, a short splice variant of BECN1, functions in mitophagy

Bing Cheng et al.

AUTOPHAGY (2015)

Review Biochemistry & Molecular Biology

UPR, autophagy, and mitochondria crosstalk underlies the ER stress response

Daniela Senft et al.

TRENDS IN BIOCHEMICAL SCIENCES (2015)

Article Cell Biology

ER stress induces NLRP3 inflammasome activation and hepatocyte death

C. Lebeaupin et al.

CELL DEATH & DISEASE (2015)

Article Cardiac & Cardiovascular Systems

Endogenous Drp1 Mediates Mitochondrial Autophagy and Protects the Heart Against Energy Stress

Yoshiyuki Ikeda et al.

CIRCULATION RESEARCH (2015)

Article Immunology

H2S Increases Survival during Sepsis: Protective Effect of CHOP Inhibition

Marcella Ferlito et al.

JOURNAL OF IMMUNOLOGY (2014)

Article Pathology

Critical Role of Foxo3a in Alcohol-Induced Autophagy and Hepatotoxicity

Hong-Min Ni et al.

AMERICAN JOURNAL OF PATHOLOGY (2013)

Review Biochemistry & Molecular Biology

Current knowledge on oxidative stress in hepatic ischemia/reperfusion

M. Elias-Miro et al.

FREE RADICAL RESEARCH (2013)

Article Biochemistry & Molecular Biology

C/EBP Homologous Protein-induced Macrophage Apoptosis Protects Mice from Steatohepatitis

Harmeet Malhi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2013)

Article Gastroenterology & Hepatology

CHOP is a critical regulator of acetaminophen-induced hepatotoxicity

Dotan Uzi et al.

JOURNAL OF HEPATOLOGY (2013)

Article Multidisciplinary Sciences

Autophagosomes form at ER-mitochondria contact sites

Maho Hamasaki et al.

NATURE (2013)

Review Cell Biology

The unfolded protein response: controlling cell fate decisions under ER stress and beyond

Claudio Hetz

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)

Article Gastroenterology & Hepatology

Dysregulation of the unfolded protein response in db/db mice with diet-induced steatohepatitis

Mary E. Rinella et al.

HEPATOLOGY (2011)

Review Gastroenterology & Hepatology

Endoplasmic reticulum stress in liver disease

Harmeet Malhi et al.

JOURNAL OF HEPATOLOGY (2011)

Article Multidisciplinary Sciences

ER Tubules Mark Sites of Mitochondrial Division

Jonathan R. Friedman et al.

SCIENCE (2011)

Article Cardiac & Cardiovascular Systems

Inhibiting Mitochondrial Fission Protects the Heart Against Ischemia/Reperfusion Injury

Sang-Bing Ong et al.

CIRCULATION (2010)

Article Gastroenterology & Hepatology

Stress Signaling in the Methionine-Choline-Deficient Model of Murine Fatty Liver Disease

Russell K. Soon et al.

GASTROENTEROLOGY (2010)

Review Biotechnology & Applied Microbiology

Cell death and endoplasmic reticulum stress: disease relevance and therapeutic opportunities

Inki Kim et al.

NATURE REVIEWS DRUG DISCOVERY (2008)

Article Biochemistry & Molecular Biology

Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bc12 and perturbing the cellular redox state

KD McCullough et al.

MOLECULAR AND CELLULAR BIOLOGY (2001)