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Cutting Edge: Reactive Oxygen Species Inhibitors Block Priming, but Not Activation, of the NLRP3 Inflammasome
Franz Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2011)
Regulator of G-Protein Signaling-10 Negatively Regulates NF-κB in Microglia and Neuroprotects Dopaminergic Neurons in Hemiparkinsonian Rats
Jae-Kyung Lee et al.
JOURNAL OF NEUROSCIENCE (2011)
Imputation of sequence variants for identification of genetic risks for Parkinson's disease: a meta-analysis of genome-wide association studies
Michael A. Nalls et al.
LANCET (2011)
A role for mitochondria in NLRP3 inflammasome activation
Rongbin Zhou et al.
NATURE (2011)
Non-canonical inflammasome activation targets caspase-11
Nobuhiko Kayagaki et al.
NATURE (2011)
Use of ibuprofen and risk of Parkinson disease
Xiang Gao et al.
NEUROLOGY (2011)
Clinical Progression in Parkinson Disease and the Neurobiology of Axons
Hsiao-Chun Cheng et al.
ANNALS OF NEUROLOGY (2010)
Trafficking of immune cells in the central nervous system
Emma H. Wilson et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Cutting Edge: Critical Role for PYCARD/ASC in the Development of Experimental Autoimmune Encephalomyelitis
Patrick J. Shaw et al.
JOURNAL OF IMMUNOLOGY (2010)
NLRP3 Plays a Critical Role in the Development of Experimental Autoimmune Encephalomyelitis by Mediating Th1 and Th17 Responses
Denis Gris et al.
JOURNAL OF IMMUNOLOGY (2010)
The Inflammasome Sensor, NLRP3, Regulates CNS Inflammation and Demyelination via Caspase-1 and Interleukin-18
Sushmita Jha et al.
JOURNAL OF NEUROSCIENCE (2010)
Common genetic variation in the HLA region is associated with late-onset sporadic Parkinson's disease
Taye H. Hamza et al.
NATURE GENETICS (2010)
Mutant superoxide dismutase 1-induced IL-1β accelerates ALS pathogenesis
Felix Meissner et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
NLRP3 inflammasome activation: the convergence of multiple signalling pathways on ROS production?
Jurg Tschopp et al.
NATURE REVIEWS IMMUNOLOGY (2010)
How mitochondria produce reactive oxygen species
Michael P. Murphy
BIOCHEMICAL JOURNAL (2009)
Glyburide inhibits the Cryopyrin/Nalp3 inflammasome
Mohamed Lamkanfi et al.
JOURNAL OF CELL BIOLOGY (2009)
Neuronal death in Alzheimer's disease and therapeutic opportunities
Rossen Donev et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2009)
Cutting Edge: NF-κB Activating Pattern Recognition and Cytokine Receptors License NLRP3 Inflammasome Activation by Regulating NLRP3 Expression
Franz G. Bauernfeind et al.
JOURNAL OF IMMUNOLOGY (2009)
CNS Infiltration of Peripheral Immune Cells: D-Day for Neurodegenerative Disease?
Kavon Rezai-Zadeh et al.
JOURNAL OF NEUROIMMUNE PHARMACOLOGY (2009)
The analysis of IL-1 beta and its naturally occurring inhibitors in multiple sclerosis: The elevation of IL-1 receptor antagonist and IL-1 receptor type II after steroid therapy
Irena Dujmovic et al.
JOURNAL OF NEUROIMMUNOLOGY (2009)
Initial clinical manifestations of Parkinson's disease: features and pathophysiological mechanisms
Maria C. Rodriguez-Oroz et al.
LANCET NEUROLOGY (2009)
Brain multiple sclerosis-like lesions in a patient with Muckle-Wells syndrome
Sandrine Compeyrot-Lacassagne et al.
RHEUMATOLOGY (2009)
The NALP3 inflammasome is involved in the innate immune response to amyloid-β
Annett Halle et al.
NATURE IMMUNOLOGY (2008)
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
Manuela Neumann et al.
SCIENCE (2006)
The aggregation and fibrillation of α-synuclein
Anthony L. Fink
ACCOUNTS OF CHEMICAL RESEARCH (2006)
Cryopyrin activates the inflammasome in response to toxins and ATP
S Mariathasan et al.
NATURE (2006)
Medical progress: Multiple sclerosis - The plaque and its pathogenesis
EM Frohman et al.
NEW ENGLAND JOURNAL OF MEDICINE (2006)
Resolution of inflammation: The beginning programs the end
CN Serhan et al.
NATURE IMMUNOLOGY (2005)
Temporal relationship between elevation of Epstein-Barr virus antibody titers and initial onset of neurological symptoms in multiple sclerosis
LI Levin et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2005)
IKKα limits macrophage NF-κB activation and contributes to the resolution of inflammation
T Lawrence et al.
NATURE (2005)
Apoptosis, pyroptosis, and necrosis: Mechanistic description of dead and dying eukaryotic cells
SL Fink et al.
INFECTION AND IMMUNITY (2005)
Molecular pathogenesis of Parkinson disease
JL Eriksen et al.
ARCHIVES OF NEUROLOGY (2005)
Evidence of widespread cerebral microglial activation in amyotrophic lateral sclerosis:: an [11C](R)-PK11195 positron emission tomography study
MR Turner et al.
NEUROBIOLOGY OF DISEASE (2004)
α-synuclein locus duplication as a cause of familial Parkinson's disease
MC Chartier-Harlin et al.
LANCET (2004)
Increased expression of caspase-1 and interleukin-18 in peripheral blood mononuclear cells in patients with multiple sclerosis
WX Huang et al.
MULTIPLE SCLEROSIS JOURNAL (2004)
α-synuclein locus triplication causes Parkinson's disease
AB Singleton et al.
SCIENCE (2003)
Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease
HL Chen et al.
ARCHIVES OF NEUROLOGY (2003)
Staging of brain pathology related to sporadic Parkinson's disease
H Braak et al.
NEUROBIOLOGY OF AGING (2003)
Interleukin 1 genotypes in multiple sclerosis and relationship to disease severity
CLA Mann et al.
JOURNAL OF NEUROIMMUNOLOGY (2002)
Production of IL-1β and IL-1Ra as risk factors for susceptibility and progression of relapse-onset multiple sclerosis
BA de Jong et al.
JOURNAL OF NEUROIMMUNOLOGY (2002)
Rapid secretion of interleukin-1β by microvesicle shedding
A MacKenzie et al.
IMMUNITY (2001)
Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
HM Hoffman et al.
NATURE GENETICS (2001)
Cytokines and acute neurodegeneration
SM Allan et al.
NATURE REVIEWS NEUROSCIENCE (2001)
Identification of a locus on chromosome 1q44 for familial cold urticaria
HM Hoffman et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2000)
Staging of multiple sclerosis (MS) lesions: pathology of the time frame of MS
P van der Valk et al.
NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY (2000)