Recent advances of innovative and high-efficiency stationary phases for chromatographic separations

Advances in chromatographic technology depend to a large extent on the development of novel stationary phases with enhanced separation efficiency to meet the ever-growing demands for highly selective and sensitive detection of diverse analytes. This review article specifically highlights the most recent advances of the newly developed efficient chromatographic separation materials in 2020-2021, mainly focusing on their novel synthesis strategies, performance evaluation, as well as their latest applications in hydrophilic interaction chromatography and chiral separation that are the research hotspots and have received the most attention. The purpose of this article is to put the state-of-art of multifunctional stationary phases into perspective, enabling the readers to have a comprehensive overview and insight into their significance in current and future separation technologies. (C) 2022 Elsevier B.V. All rights reserved.

Automated summary

This article reviews the recent advances in efficient chromatographic separation materials developed in 2020-2021, focusing on their synthesis strategies, performance evaluation, and applications in hydrophilic interaction chromatography and chiral separation. The review provides readers with a comprehensive overview of the significance of these materials in current and future separation technologies.