Journal
TETRAHEDRON LETTERS
Volume 103, Issue -, Pages -Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2022.153991
Keywords
Pyrrolo[2; 1-a]isoquinolines; Three-component reactions; Domino reaction; NH-acids; Terminal alkynes
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The three-component domino reaction involving 1-aroyl-3,4-dihydroisoquinolines, terminal alkynes, and cyclic NH-acids is a new method for the synthesis of 5,6-dihydropyrrolo[2,1-a]isoquinolines containing cyclic nitrogen-containing fragments at position 3.
The three-component domino reaction involving 1-aroyl-3,4-dihydroisoquinolines, terminal alkynes, and cyclic NH-acids is a new method for the synthesis of 5,6-dihydropyrrolo[2,1-a]isoquinolines containing in position 3, cyclic nitrogen-containing fragments. The transformation is performed under microwave irra-diation in dry acetonitrile at 130 degrees C.CO 2022 Elsevier Ltd. All rights reserved.
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