Chiral membranes for enantiomer separation: A comprehensive review

Chirality is a basic property of nature. Chiral compounds are widely used in medicine. The pharmacological action of enantiomers in human body varies widely or even opposites. Therefore, the purity of chiral compounds plays an important role in human health and safety. Enantiomer separation is a necessary process to obtain pure chiral compounds. How to efficiently separate enantiomers has been a hot research topic in the world. Chiral membrane separation has many advantages and has great potential in enantiomer separation. The key to chiral membrane separation is the development of membrane materials. At present, many promising new materials have emerged in the field of chiral membrane separation. Unfortunately, systematic reviews of chiral membrane separation are few and far between due to the wide range of disciplines involved. Therefore, Based on chiral membrane materials and starting from the mechanism of chiral membrane separation, this paper systematically describes the research progress in the chiral separation of graphene material membrane, metal-organic framework membrane and polymer membrane. In addition, the challenges and prospects of chiral membrane separation are analyzed. It is hoped that it can be helpful for the further study of chiral membrane separation.

Automated summary

Chirality is a fundamental property of nature, and chiral compounds are widely used in medicine. The purity of chiral compounds plays a crucial role in human health and safety as the pharmacological actions of enantiomers in the human body can vary widely or even be opposite. Chiral membrane separation, which has many advantages, is a promising method for enantiomer separation. The development of membrane materials is a key aspect of chiral membrane separation. This paper systematically describes the research progress in the chiral separation of graphene material membrane, metal-organic framework membrane, and polymer membrane, while also analyzing the challenges and prospects of chiral membrane separation.