4.6 Article

Chronic obstructive pulmonary disease (COPD) mortality trends worldwide: An update to 2019

Journal

RESPIROLOGY
Volume 27, Issue 11, Pages 941-950

Publisher

WILEY
DOI: 10.1111/resp.14328

Keywords

chronic obstructive pulmonary disease; COPD; epidemiology; mortality; trend; worldwide

Funding

  1. Associazione Italiana per la Ricerca sul Cancro [IG2019 22987]

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Based on the analysis of data from the World Health Organization (WHO), the global mortality rate from chronic obstructive pulmonary disease (COPD) has been decreasing steadily, but there are several countries where the mortality rate for women is increasing. These trends are mainly attributed to changes in smoking habits, as well as the impact of air pollution and occupational exposures.
Background and objective Chronic obstructive pulmonary disease (COPD) incidence, prevalence, mortality and socioeconomic burden are considerable and vary across countries. The aim of the present study was to update the analysis of COPD mortality worldwide using data from the World Health Organization (WHO) up to 2019. Methods We obtained COPD mortality and population data for 22 European countries and the European Union (EU) as a whole, 10 American countries and six other countries from the WHO mortality database. We calculated age-standardized mortality rates in both sexes and examined trends by country with joinpoint analysis between 1994 and 2019. Results Between 2005-2007 and 2015-2017, overall COPD mortality decreased in EU men (-16.3%) but increased in women (12.7%) to reach rates of 14.0/100,000 in men and of 6.4/100,000 in women. In the United States, mortality declined in men to 21.3/100,000 but rose in women to 18.3/100,000. Mortality declined in most Latin American countries and all Asian countries, while an increase in Australian women was observed. Conclusion A steady decrease in COPD mortality was observed in most of countries for men, whilst a different trend was observed in women in several countries. These trends are largely explained by changes in smoking habits, with an additional contribution of air pollution and occupational exposures. Despite past and ongoing tobacco control initiatives, this condition still remains a leading cause of death, in particular in countries with lower socio-demographic indices.

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