4.7 Article

Deep Learning Detects Changes Indicative of Axial Spondyloarthritis at MRI of Sacroiliac Joints

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Summary: This population-based cohort study identified factors associated with MRI lesions suggestive of axial spondyloarthritis (axSpA) in individuals aged <45 years. The presence and extension of bone marrow edema (BME) in spinal and sacroiliac joints (SIJ) were strongly associated with factors such as delivery during the last year, HLA-B27 positivity, body mass index, and back pain. These findings support the hypothesis of mechanical strain contributing to BME in the general population aged <45 years and suggest that HLA-B27 positivity may play a role in severity rather than susceptibility to SIJ-BME.

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