4.6 Article

Ca2+ attenuates nucleation activity of leiomodin

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Structural insights into the tropomodulin assembly at the pointed ends of actin filaments

Dmitri Tolkatchev et al.

Summary: In this study, the interactions between tropomyosin residues and two tropomyosin-binding sites of tropomodulin were mapped, and three-dimensional models of the tropomodulin/tropomyosin complex for each site were generated. The models were refined through molecular dynamics simulations and validated by constructing a self-consistent three-dimensional model of tropomodulin assembly at the pointed end. The pointed-end Tmod assembly model provides new insights into how Tmod binding tightly controls the dynamics at the pointed end.

PROTEIN SCIENCE (2021)

Article Biochemistry & Molecular Biology

Insight into Calcium-Binding Motifs of Intrinsically Disordered Proteins

Estella A. Newcombe et al.

Summary: Motifs within proteins help categorize their functions;Intrinsically disordered proteins (IDPs) rich in short linear motifs with various roles;Study found calcium-binding motifs in IDPs may serve various underreported structural and functional roles.

BIOMOLECULES (2021)

Article Cell Biology

Troponin structure and function: a view of recent progress

Steven Marston et al.

JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY (2020)

Review Biochemistry & Molecular Biology

Assembly and Maintenance of Sarcomere Thin Filaments and Associated Diseases

Kendal Prill et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)

Article Biochemistry & Molecular Biology

Leiomodin creates a leaky cap at the pointed end of actin-thin filaments

Dmitri Tolkatchev et al.

PLOS BIOLOGY (2020)

Article Chemistry, Multidisciplinary

Nanothermometry Reveals Calcium-Induced Remodeling of Myosin

Eric R. Kuhn et al.

NANO LETTERS (2018)

Article Multidisciplinary Sciences

Loss of LMOD1 impairs smooth muscle cytocontractility and causes megacystis microcolon intestinal hypoperistalsis syndrome in humans and mice

Danny Halim et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)

Review Biophysics

Tropomodulins and Leiomodins: Actin Pointed End Caps and Nucleators in Muscles

Velia M. Fowler et al.

BIOPHYSICAL JOURNAL (2017)

Article Biochemistry & Molecular Biology

Localization of the binding interface between leiomodin-2 and α-tropomyosin

Mert Colpan et al.

BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2016)

Article Multidisciplinary Sciences

Phosphorylation and calcium antagonistically tune myosin-binding protein C's structure and function

Michael J. Previs et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)

Article Medicine, Research & Experimental

Severe myopathy in mice lacking the MEF2/SRF-dependent gene leiomodin-3

Bercin K. Cenik et al.

JOURNAL OF CLINICAL INVESTIGATION (2015)

Article Multidisciplinary Sciences

Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality

Christopher T. Pappas et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Article Multidisciplinary Sciences

How Leiomodin and Tropomodulin use a common fold for different actin assembly functions

Malgorzata Boczkowska et al.

NATURE COMMUNICATIONS (2015)

Article Medicine, Research & Experimental

Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy

Michaele Yuen et al.

JOURNAL OF CLINICAL INVESTIGATION (2014)

Article Multidisciplinary Sciences

Mechanism of actin filament pointed-end capping by tropomodulin

Jampani Nageswara Rao et al.

SCIENCE (2014)

Article Biophysics

Altered mechanical properties of titin immunoglobulin domain 27 in the presence of calcium

Michael M. DuVall et al.

EUROPEAN BIOPHYSICS JOURNAL WITH BIOPHYSICS LETTERS (2013)

Article Biochemistry & Molecular Biology

(DP2)-P-2: database of disordered protein predictions

Matt E. Oates et al.

NUCLEIC ACIDS RESEARCH (2013)

Article Biochemistry & Molecular Biology

Data mining of metal ion environments present in protein structures

Heping Zheng et al.

JOURNAL OF INORGANIC BIOCHEMISTRY (2008)

Article Multidisciplinary Sciences

Leiomodin is an actin filament nucleator in muscle cells

David Chereau et al.

SCIENCE (2008)

Article Biochemistry & Molecular Biology

Molecular basis of tropomyosin binding to tropomodulin, an actin-capping protein

Alla S. Kostyukova et al.

JOURNAL OF MOLECULAR BIOLOGY (2007)

Article Biochemistry & Molecular Biology

Leiomodin/tropomyosin interactions are isoform specific

Alla S. Kostyukova

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2007)

Article Biochemistry & Molecular Biology

OPTIMIZER:: a web server for optimizing the codon usage of DNA sequences

Pere Puigbo et al.

NUCLEIC ACIDS RESEARCH (2007)

Article Biochemistry & Molecular Biology

Tropomodulin binds two tropomyosins: A novel model for actin filament capping

Alla S. Kostyukova et al.

BIOCHEMISTRY (2006)

Article Biochemical Research Methods

Using circular dichroism spectra to estimate protein secondary structure

Norma J. Greenfield

NATURE PROTOCOLS (2006)

Article Biochemistry & Molecular Biology

Divalent metal cation binding properties of human prothymosin α

NV Chichkova et al.

EUROPEAN JOURNAL OF BIOCHEMISTRY (2000)

Article Biochemistry & Molecular Biology

Zn2+-mediated structure formation and compaction of the Natively unfolded human prothymosin α

VN Uversky et al.

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2000)