4.6 Article

Nanocomposite coatings for the prevention of surface contamination by coronavirus

Journal

PLOS ONE
Volume 17, Issue 8, Pages -

Publisher

PUBLIC LIBRARY SCIENCE
DOI: 10.1371/journal.pone.0272307

Keywords

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Funding

  1. Israel Innovation Authority
  2. Israel Science Foundations: F.I.R.S.T. [2058/18]
  3. Israel Ministry of Science and Technology
  4. Ariane de Rothschild Women's Doctoral scholar ships program for outstanding female Ph.D. students, and Israel Scholarship Education Foundation (ISEF)

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The current Covid-19 pandemic has had a significant impact on various aspects of our lives. In addition to airborne transmission, the SARS-CoV-2 virus is also widely present on surfaces that we come into contact with daily. Therefore, controlling the pandemic requires reducing potential infections through contaminated surfaces. Researchers have developed composite materials containing copper and cupric oxide nanoparticles, which exhibit strong antiviral properties and can be used as long-term antiviral coatings against various pathogens, including SARS-CoV-2.
The current Covid-19 pandemic has a profound impact on all aspects of our lives. Aside from contagion by aerosols, the presence of the SARS-CoV-2 is ubiquitous on surfaces that millions of people handle daily. Therefore, controlling this pandemic involves the reduction of potential infections via contaminated surfaces. We developed antiviral surfaces by preparing suspensions of copper and cupric oxide nanoparticles in two different polymer matrices, poly(methyl methacrylate) and polyepoxide. For total copper contents as low as 5%, the composite material showed remarkable antiviral properties against the HCoV-OC43 human coronavirus and against a model lentivirus and proved well-resistant to accelerated aging conditions. Importantly, we showed that the Cu/CuO mixture showed optimal performances. This product can be implemented to produce a simple and inexpensive coating with long-term antiviral properties and will open the way to developing surface coatings against a broad spectrum of pathogens including SARS-CoV-2.

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