Phytochemical characterization and antioxidant activity of the aerial part extracts from two species of Matthiola wild in Sicily: Matthiola sinuata and M. tricuspidata (Brassicaceae)

As part of a project aimed at investigating the specific and intraspecific taxa of Matthiola which grow spontaneously in Sicily (Italy), in this work our research has been focused on Matthiola tricuspidata and Matthiola sinuata. The phenolic and volatile compounds of the hydroalcoholic extracts from the aerial parts of the selected species have been characterized by HPLC-PDA/ESI-MS and SPME-GC/MS analyses. Moreover, the antioxidant capacity in vitro (1,1-diphenyl-2-picrylhydrazil (DPPH), reducing power and Fe2+ chelating activity assays) and the toxicity (Artemia salina lethality bioassay) of the extracts were investigated. The phytochemical analyses highlighted quite different phenolic and volatile profiles in the two species. Concerning the antioxidant properties, M. tricuspidata extract resulted the most active both in the DPPH and in the reducing power tests (IC50 = 1.20 +/- 0.01 mg/mL and ASE/mL = 11.25 +/- 0.97), whereas M. sinuata extract showed better secondary antioxidant properties (IC50 = 1.32 +/- 0.02 mg/mL). The extracts resulted non-toxic in the Artemia salina lethality bioassay. Our findings indicate that both M. tricuspidata and M. sinuata represent new safe sources of bioactive compounds with antioxidant potential.

Automated summary

This study investigated the specific and intraspecific taxa of Matthiola growing in Sicily, with a focus on Matthiola tricuspidata and Matthiola sinuata. The phenolic and volatile compounds of the aerial parts of these species were characterized, and their antioxidant capacity and toxicity were evaluated. The results showed that both M. tricuspidata and M. sinuata are new safe sources of bioactive compounds with antioxidant potential.