Promoting Nerve Regeneration: Electrical Stimulation, Gene Therapy, and Beyond

Peripheral nerve injuries often result in life-altering functional deficits even with optimal management. Unlike the central nervous system, peripheral nerves have the ability to regenerate lost axons after injury; however, axonal regeneration does not equate to full restoration of function. To overcome this physiological shortcoming, advances in nerve regeneration and repair are paramount, including electrical stimulation, gene therapy, and surgical technique advancements.

Automated summary

Peripheral nerve injuries can result in life-altering functional deficits, even with the ability of peripheral nerves to regenerate axons after injury. Advances in nerve regeneration and repair, such as electrical stimulation, gene therapy, and surgical technique advancements, are crucial for overcoming the physiological shortcomings of axonal regeneration.