4.6 Article

Joint image reconstruction algorithm in Compton cameras

Journal

PHYSICS IN MEDICINE AND BIOLOGY
Volume 67, Issue 15, Pages -

Publisher

IOP Publishing Ltd
DOI: 10.1088/1361-6560/ac7b08

Keywords

Compton camera; compton imaging; hadron therapy; image reconstruction; LM-MLEM; Monte Carlo simulations; multi-layer compton telescope

Funding

  1. Spanish Ministerio de Ciencia e Innovacion, Agencia Estatal de Investigacion [FPA2017-85611-R, PID2019-110657RB-100/AEI/10.13039/501100011033]
  2. Generalitat Valenciana
  3. UVEGAtraccio de Talent
  4. SEJIGENT
  5. FPU

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This study demonstrates the benefits of using a joint image reconstruction algorithm that combines events measured in different channels of information of a Compton camera. The algorithm improves image quality, provides better estimates of displacements of high-energy gamma-ray emitting sources, and offers more stability compared to individual channels.
Objective. To demonstrate the benefits of using an joint image reconstruction algorithm based on the List Mode Maximum Likelihood Expectation Maximization that combines events measured in different channels of information of a Compton camera. Approach. Both simulations and experimental data are employed to show the algorithm performance. Main results. The obtained joint images present improved image quality and yield better estimates of displacements of high-energy gamma-ray emitting sources. The algorithm also provides images that are more stable than any individual channel against the noisy convergence that characterizes Maximum Likelihood based algorithms. Significance. The joint reconstruction algorithm can improve the quality and robustness of Compton camera images. It also has high versatility, as it can be easily adapted to any Compton camera geometry. It is thus expected to represent an important step in the optimization of Compton camera imaging.

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