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Gemcitabine-treated pancreatic cancer cell medium induces the specific CTL antitumor activity by stimulating the maturation of dendritic cells
Qingshan Pei et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2014)
Cancer cell-autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
Antonella Sistigu et al.
NATURE MEDICINE (2014)
Chemotherapy Enhances Cross-Presentation of Nuclear Tumor Antigens
Chidozie C. Anyaegbu et al.
PLOS ONE (2014)
Selective Depletion of Regulatory T Cell Subsets by Docetaxel Treatment in Patients with Nonsmall Cell Lung Cancer
Jie-Yao Li et al.
JOURNAL OF IMMUNOLOGY RESEARCH (2014)
Screening of novel immunogenic cell death inducers within the NCI Mechanistic Diversity Set
Abdul Qader Sukkurwala et al.
ONCOIMMUNOLOGY (2014)
Tumour antigens recognized by T lymphocytes: at the core of cancer immunotherapy
Pierre G. Coulie et al.
NATURE REVIEWS CANCER (2014)
Chemotherapy Alters Monocyte Differentiation to Favor Generation of Cancer-Supporting M2 Macrophages in the Tumor Microenvironment
Eveline M. Dijkgraaf et al.
CANCER RESEARCH (2013)
Inducers of immunogenic cancer cell death
Aleksandra M. Dudek et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2013)
Human CD4+CD25+Regulatory T Cells Are Sensitive to Low Dose Cyclophosphamide: Implications for the Immune Response
Daniel Heylmann et al.
PLOS ONE (2013)
Effects of conventional therapeutic interventions on the number and function of regulatory T cells
Mario Roselli et al.
ONCOIMMUNOLOGY (2013)
The Immunological Impact of Neoadjuvant Chemotherapy on the Tumor Microenvironment of Esophageal Squamous Cell Carcinoma
Takahiro Tsuchikawa et al.
ANNALS OF SURGICAL ONCOLOGY (2012)
Premortem autophagy determines the immunogenicity of chemotherapy-induced cancer cell death
Isabelle Martins et al.
AUTOPHAGY (2012)
Tumor-infiltrating lymphocytes are correlated with response to neoadjuvant chemotherapy in triple-negative breast cancer
Makiko Ono et al.
BREAST CANCER RESEARCH AND TREATMENT (2012)
Defining the Molecular Signature of Chemotherapy-Mediated Lung Tumor Phenotype Modulation and Increased Susceptibility to T-Cell Killing
Sofia R. Gameiro et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2012)
The chemotherapeutic drug oxaliplatin differentially affects blood DC function dependent on environmental cues
Jurjen Tel et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2012)
Chemotherapy broadens the range of tumor antigens seen by cytotoxic CD8+ T cells in vivo
Connie Jackaman et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2012)
A reduction of recipient regulatory T cells by cyclophosphamide contributes to an anti-tumor effect of nonmyeloablative allogeneic stem cell transplantation in mice
Ario Takeuchi et al.
INTERNATIONAL JOURNAL OF CANCER (2012)
Application of paclitaxel in low non-cytotoxic doses supports vaccination with melanoma antigens in normal mice
Alexandra Sevko et al.
JOURNAL OF IMMUNOTOXICOLOGY (2012)
Alterations in tumor necrosis factor signaling pathways are associated with cytotoxicity and resistance to taxanes: a study in isogenic resistant tumor cells
Jason A. Sprowl et al.
BREAST CANCER RESEARCH (2012)
Chemotherapy Induces Intratumoral Expression of Chemokines in Cutaneous Melanoma, Favoring T-cell Infiltration and Tumor Control
Michelle Hong et al.
CANCER RESEARCH (2011)
Anti-tumour synergy of cytotoxic chemotherapy and anti-CD40 plus CpG-ODN immunotherapy through repolarization of tumour-associated macrophages
Ilia N. Buhtoiarov et al.
IMMUNOLOGY (2011)
Gemcitabine depletes regulatory T-cells in human and mice and enhances triggering of vaccine-specific cytotoxic T-cells
Lorna Rettig et al.
INTERNATIONAL JOURNAL OF CANCER (2011)
In situ immune response after neoadjuvant chemotherapy for breast cancer predicts survival
Sylvain Ladoire et al.
JOURNAL OF PATHOLOGY (2011)
Time-dependent cytotoxic drugs selectively cooperate with IL-18 for cancer chemoimmunotherapy
Ioannis Alagkiozidis et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
Ipilimumab plus Dacarbazine for Previously Untreated Metastatic Melanoma
Caroline Robert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2011)
Restoration of the immunogenicity of cisplatin-induced cancer cell death by endoplasmic reticulum stress
I. Martins et al.
ONCOGENE (2011)
Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice
Mickael Michaud et al.
SCIENCE (2011)
Tumor-infiltrating lymphocytes predict response to anthracycline-based chemotherapy in estrogen receptor-negative breast cancer
Nathan R. West et al.
BREAST CANCER RESEARCH (2011)
Cyclophosphamide enhances immunity by modulating the balance of dendritic cell subsets in lymphoid organs
Takeshi Nakahara et al.
BLOOD (2010)
Differential effects of Paclitaxel on dendritic cell function
Justin John et al.
BMC IMMUNOLOGY (2010)
Pre-treatment with chemotherapy can enhance the antigenicity and immunogenicity of tumours by promoting adaptive immune responses
W. M. Liu et al.
BRITISH JOURNAL OF CANCER (2010)
Paclitaxel enhances early dendritic cell maturation and function through TLR4 signaling in mice
Lukas W. Pfannenstiel et al.
CELLULAR IMMUNOLOGY (2010)
A Novel Chemoimmunomodulating Property of Docetaxel: Suppression of Myeloid-Derived Suppressor Cells in Tumor Bearers
Krithika N. Kodumudi et al.
CLINICAL CANCER RESEARCH (2010)
Tumor-Associated Lymphocytes As an Independent Predictor of Response to Neoadjuvant Chemotherapy in Breast Cancer
Carsten Denkert et al.
JOURNAL OF CLINICAL ONCOLOGY (2010)
Cyclophosphamide Induces Dynamic Alterations in the Host Microenvironments Resulting in a Flt3 Ligand-Dependent Expansion of Dendritic Cells
Mohamed L. Salem et al.
JOURNAL OF IMMUNOLOGY (2010)
Administration of Cyclophosphamide Changes the Immune Profile of Tumor-bearing Mice
Pu Liu et al.
JOURNAL OF IMMUNOTHERAPY (2010)
Secondary fibrosarcoma of the brain stem treated with cyclophosphamide and Imatinib
Daniela Alexandru et al.
JOURNAL OF NEURO-ONCOLOGY (2010)
Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
F. Stephen Hodi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2010)
Immunogenic death of colon cancer cells treated with oxaliplatin
A. Tesniere et al.
ONCOGENE (2010)
Immune Response During Therapy With Cisplatin or Radiation for Human Papillomavirus-Related Head and Neck Cancer
William C. Spanos et al.
ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY (2009)
Human leukocyte antigen class I expression is an independent prognostic factor in advanced ovarian cancer resistant to first-line platinum chemotherapy
M. Shehata et al.
BRITISH JOURNAL OF CANCER (2009)
Cisplatin primes murine peritoneal macrophages for enhanced expression of nitric oxide, proinflammatory cytokines, TLRs, transcription factors and activation of MAP kinases upon co-incubation with L929 cells
Puja Chauhan et al.
IMMUNOBIOLOGY (2009)
Chemotherapy enhances vaccine-induced antitumor immunity in melanoma patients
Paola Nistico et al.
INTERNATIONAL JOURNAL OF CANCER (2009)
Regular Dose of Gemcitabine Induces an Increase in CD14+ Monocytes and CD11c+ Dendritic Cells in Patients with Advanced Pancreatic Cancer
Atsuko Soeda et al.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2009)
Timed Sequential Treatment With Cyclophosphamide, Doxorubicin, and an Allogeneic Granulocyte-Macrophage Colony-Stimulating Factor-Secreting Breast Tumor Vaccine: A Chemotherapy Dose-Ranging Factorial Study of Safety and Immune Activation
Leisha A. Emens et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Chemotherapeutic Agents in Noncytotoxic Concentrations Increase Antigen Presentation by Dendritic Cells via an IL-12-Dependent Mechanism
Galina V. Shurin et al.
JOURNAL OF IMMUNOLOGY (2009)
Recovery from Cyclophosphamide-Induced Lymphopenia Results in Expansion of Immature Dendritic Cells Which Can Mediate Enhanced Prime-Boost Vaccination Antitumor Responses In Vivo When Stimulated with the TLR3 Agonist Poly(I:C)
Mohamed L. Salem et al.
JOURNAL OF IMMUNOLOGY (2009)
The Immune Adjuvant Properties of Front-line Carboplatin-Paclitaxel: A Randomized Phase 2 Study of Alternative Schedules of Intravenous Oregovomab Chemoimmunotherapy in Advanced Ovarian Cancer
Patricia Braly et al.
JOURNAL OF IMMUNOTHERAPY (2009)
Chemomodulation of human dendritic cell function by antineoplastic agents in low noncytotoxic concentrations
Ramon Kaneno et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2009)
Influence of cyclophosphamide and its metabolic products on the activity of peritoneal macrophages in mice
Krzysztof Bryniarski et al.
PHARMACOLOGICAL REPORTS (2009)
Influence of cyclophosphamide and its metabolic products on the activity of peritoneal macrophages in mice
Krzysztof Bryniarski et al.
PHARMACOLOGICAL REPORTS (2009)
Tumor-infiltrating lymphocytes and perforation in colon cancer predict positive response to 5-fluorouracil chemotherapy
Melinda Morris et al.
CLINICAL CANCER RESEARCH (2008)
Allogeneic granulocyte macrophage colony-stimulating factor-secreting tumor immunotherapy alone or in sequence with cyclophosphamide for metastatic pancreatic cancer: A pilot study of safety, feasibility, and immune activation
Dan Laheru et al.
CLINICAL CANCER RESEARCH (2008)
Pretreatment with cisplatin enhances E7-specific CD8+ T-cell mediated antitumor immunity induced by DNA vaccination
Chih-Wen Tseng et al.
CLINICAL CANCER RESEARCH (2008)
Chemotherapy and tumor immunity: an unexpected collaboration
Leisha A. Emens
FRONTIERS IN BIOSCIENCE-LANDMARK (2008)
Adoptive Cell Therapy for Patients With Metastatic Melanoma: Evaluation of Intensive Myeloablative Chemoradiation Preparative Regimens
Mark E. Dudley et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Increase of CD4+CD25+ regulatory T cells in the peripheral blood of patients with metastatic carcinoma:: a Phase I clinical trial using cyclophosphamide and immunotherapy to eliminate CD4+CD25+ T lymphocytes
S. Audia et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2007)
Taxol increases the amount and T cell-activating ability of self-immune stimulatory multimolecular complexes found in ovarian cancer cells
Naotake Tsuda et al.
CANCER RESEARCH (2007)
Bortezomib enhances dendritic cell (DC)-mediated induction of immunity to human myeloma via exposure of cell surface heat shock protein 90 on dying tumor cells: therapeutic implications
Radek Spisek et al.
BLOOD (2007)
Metronomic cyclophosphamide regimen selectively depletes CD4+ CD25+ regulatory T cells and restores T and NK effector functions in end stage cancer patients
Francois Ghiringhelli et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2007)
Cyclophosphamide enhances the antitumor efficacy of adoptively transferred immune cells through the induction of cytokine expression, B-cell and T-cell homeostatic proliferation, and specific tumor infiltration
Laura Bracci et al.
CLINICAL CANCER RESEARCH (2007)
Calreticulin exposure dictates the immunogenicity of cancer cell death
Michel Obeid et al.
NATURE MEDICINE (2007)
Dendritic cell-based vaccination combined with gemcitabine increases survival in a murine pancreatic carcinoma model
C. Bauer et al.
GUT (2007)
Type, density, and location of immune cells within human colorectal tumors predict clinical outcome
Jerom Galon et al.
SCIENCE (2006)
Cancer Therapy-Induced Residual Bone Marrow Injury: Mechanisms of Induction and Implication for Therapy
Yong Wang et al.
CURRENT CANCER THERAPY REVIEWS (2006)
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death
N Casares et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Effect of gemcitabine on immune cells in subjects with adenocarcinoma of the pancreas
JMD Plate et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2005)
Allogeneic dendritic cell vaccination against metastatic renal cell carcinoma with or without cyclophosphamide
L Höltl et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2005)
Adoptive cell transfer therapy following non-myeloablative but lymphodepleting chemotherapy for the treatment of patients with refractory metastatic melanoma
ME Dudley et al.
JOURNAL OF CLINICAL ONCOLOGY (2005)
CD4+CD25+ regulatory T cells suppress tumor immunity but are sensitive to cyclophosphamide which allows immunotherapy of established tumors to be curative
F Ghiringhelli et al.
EUROPEAN JOURNAL OF IMMUNOLOGY (2004)
Augmentation of chemotherapy-induced cytokine production by expression of the platelet-activating factor receptor in a human epithelial carcinoma cell line
M Darst et al.
JOURNAL OF IMMUNOLOGY (2004)
Exposure to paclitaxel or vinblastine down-regulates CD11a and CD54 expression by P815 mastocytoma cells and renders the tumor cells resistant to killing by nonspecific cytotoxic T lymphocytes induced with anti-CD3 antibody
CL Zhao et al.
CANCER IMMUNOLOGY IMMUNOTHERAPY (2003)
Increased expression of CEA and MHC class I in colorectal cancer cell lines exposed to chemotherapy drugs
S Ohtsukasa et al.
JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY (2003)
Cellular and molecular aspects of drugs of the future: oxaliplatin
AM Di Francesco et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2002)
Mouse toll-like receptor 4•MD-2 complex mediates lipopolysaccharide-mimetic signal transduction by taxol
K Kawasaki et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)