Refractory angiolymphoid hyperplasia with eosinophilia: Complete resolution with low dose thalidomide

Angiolymphoid hyperplasia with eosinophilia (ALHE) is a difficult-to-treat and rare benign vascular proliferative condition which presents as painless, solitary, or multiple vascular papules or nodules in the head and neck area, with predilection for the ear. We report a case of ALHE that failed multiple therapeutic interventions but achieved complete resolution when treated with thalidomide.

Automated summary

ALHE is a rare benign vascular proliferative condition that usually occurs in the head and neck area, particularly near the ear, presenting as painless vascular papules or nodules. We report a case of ALHE that failed multiple therapeutic interventions but achieved complete resolution when treated with thalidomide.