Cadaveric donor specimens and serological testing for SARS-CoV-2

Article Surgery

Donor to recipient transmission of SARS-CoV-2 by lung transplantation despite negative donor upper respiratory tract testing

Daniel R. Kaul et al.

Summary: This case report highlights a proven transmission of SARS-CoV-2 from a lung donor to recipient, with sequence analysis confirming the donor origin of infection in both the recipient and a healthcare worker. It emphasizes the importance of testing lower respiratory tract specimens from potential lung donors and enhancing personal protective equipment for healthcare workers involved in lung procurement and transplantation.

AMERICAN JOURNAL OF TRANSPLANTATION (2021)

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Review Surgery

The impact of COVID-19 on kidney transplantation and the kidney transplant recipient - One year into the pandemic

Pascale Khairallah et al.

Summary: The COVID-19 pandemic has significantly impacted kidney transplantation, affecting patient and allograft survival, transplant referrals, organ donation rates, and clinical management decisions. Transplant centers and physicians have made critical decisions considering patient safety and resource utilization. New considerations have arisen with the administration of COVID vaccines.

TRANSPLANT INTERNATIONAL (2021)

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Article Virology

SARS Coronavirus-2 Microneutralisation and Commercial Serological Assays Correlated Closely for Some but Not All Enzyme Immunoassays

Gregory J. Walker et al.

Summary: Serological testing for SARS-CoV-2-specific antibodies plays a crucial role in understanding COVID-19 prevalence, incidence, and immune response. The study found a strong correlation between neutralising antibodies and certain commercially available EIAs, indicating their potential use in assessing protection post-infection or vaccination, and in screening convalescent plasma donors. The type of antibody and target antigen used in the assays were identified as crucial determinants of assay performance.

VIRUSES-BASEL (2021)

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Review Transplantation

The solid organ transplant recipient with SARS-CoV-2 infection

Justin C. Laracy et al.

Summary: The COVID-19 pandemic poses a major challenge to global health, especially among vulnerable populations. Studies on treatment and prevention specific to solid organ transplant recipients are urgently needed.

CURRENT OPINION IN ORGAN TRANSPLANTATION (2021)

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Article Cell Biology