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Gaps and alternative surgical and non-surgical approaches in the bone fragility management: an updated review

Journal

OSTEOPOROSIS INTERNATIONAL
Volume 33, Issue 12, Pages 2467-2478

Publisher

SPRINGER LONDON LTD
DOI: 10.1007/s00198-022-06482-z

Keywords

Fracture; Fracture risk; Fragility; Gaps; Osteoporosis; Osteoporosis management

Funding

  1. F.I.R.M.O. Foundation through a grant from AgNovos

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Osteoporotic fractures are a major problem in healthcare systems worldwide. Fragility fractures of the hip have a greater impact on morbidity, mortality, and healthcare costs than other fracture sites. There is a lack of awareness of osteoporosis and most high-risk individuals do not receive adequate treatment.
Osteoporotic fractures are one of the major problems facing healthcare systems worldwide. Undoubtedly, fragility fractures of the hip represent a far greater burden in terms of morbidity, mortality, and healthcare costs than other fracture sites. However, despite the significant impact on the health and quality of life of older adults, there is a general lack of awareness of osteoporosis, which results in suboptimal care. In fact, most high-risk individuals are never identified and do not receive adequate treatment, leading to further fragility fractures and worsening health status. Furthermore, considering the substantial treatment gap and the proven cost-effectiveness of fracture prevention programs such as Fracture Liaison Services, urgent action is needed to ensure that all individuals at high risk of fragility fracture are adequately assessed and treated. Based on this evidence, the aim of our review was to (i) provide an overview and comparison of the burden and management of fragility fractures, highlighting the main gaps, and (ii) highlight the importance of using alternative approaches, both surgical and non-surgical, with the aim of implementing early prevention of osteoporotic fractures and improving the management of osteoporotic patients at imminent and/or very high risk of fracture.

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