4.8 Article

Highly Enantioselective Iridium-Catalyzed Hydrogenation of o-Amidophenyl Ketones Enabled by 1,2-Diphenylethylenediamine- Derived P,N,N-Ligands with Tertiary Amine Terminus

Related references

Note: Only part of the references are listed.
Article Chemistry, Multidisciplinary

Asymmetric Transfer Hydrogenation of Diaryl Ketones with Ethanol Catalyzed by Chiral NCP Pincer Iridium Complexes

Lu Qian et al.

Summary: The use of a chiral (NCP)Ir complex as the precatalyst allows for the asymmetric transfer hydrogenation of diaryl ketones. This method is applicable to various ortho-substituted diaryl ketones and can be conducted in gram scale under mild reaction conditions.

CHINESE JOURNAL OF CHEMISTRY (2022)

Article Chemistry, Inorganic & Nuclear

Effectiveness and Mechanism of the Ene(amido) Group in Activating Iron for the Catalytic Asymmetric Transfer Hydrogenation of Ketones

Qingquan Xue et al.

Summary: The pi-interacting ligands of diphosphino amidoene (amido) type were found to be effective in activating iron mimicking the properties of precious metals in catalytic asymmetric transfer hydrogenation of ketones. Through the synthesis of various iron precatalyst complexes and comparison experiments, the effectiveness of the ene (amido) group was demonstrated.

ORGANOMETALLICS (2021)

Article Chemistry, Multidisciplinary

Amino Acid-Functionalized Metal-Organic Frameworks for Asymmetric Base-Metal Catalysis

Rajashree Newar et al.

Summary: This study presents a strategy to develop eco-friendly asymmetric catalysts using naturally occurring amino acids and earth-abundant metals, resulting in highly active and enantioselective catalysts for hydrosilylation and hydroboration of carbonyl compounds by grafting amino acids within the pores of a metal-organic framework (MOF) and post-synthetic metalation with iron precursor. The MOF-Fe catalyst exhibited high turnover numbers and good recyclability, demonstrating higher activity and enantioselectivity compared to its homogeneous control catalyst due to the formation of robust single-site catalyst in the MOF through site-isolation.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2021)

Review Chemistry, Multidisciplinary

Asymmetric Hydrogenation: Design of Chiral Ligands and Transition Metal Complexes. Synthetic and Industrial Applications.

Jean-Pierre Genet et al.

Summary: This article focuses on the development of atropisomeric ligands and chiral transition metal complexes in asymmetric hydrogenation reactions, emphasizing the successful scaled-up syntheses of SYNPHOS and DIFLUORPHOS and their industrial and total synthesis applications. Asymmetric hydrogenation provides a powerful tool for precise stereocontrolled transformations on valuable complex molecules.

ISRAEL JOURNAL OF CHEMISTRY (2021)

Article Chemistry, Physical

Asymmetric Transfer Hydrogenation of Aryl Heteroaryl Ketones using Noyori-Ikariya Catalysts

Ye Zheng et al.

Summary: Aromatic ketones with ortho-substituents showed high enantioselectivity under asymmetric transfer hydrogenation conditions, while N-methylimidazole-containing ketones exhibited unexpected enantioselectivity switches upon variation of the opposing aromatic group. Pyrrole-containing ketones were found to be resistant to reduction in this study.

CHEMCATCHEM (2021)

Review Chemistry, Multidisciplinary

Chiral Tridentate Ligands in Transition Metal-Catalyzed Asymmetric Hydrogenation

Heng Wang et al.

Summary: Asymmetric hydrogenation of double bonds is an effective method for preparing chiral molecules, with noble metals and bidentate ligands showing remarkable reactivity. The development of chiral tridentate ligands has become increasingly important, enabling both reactivities and stereoselectivities in asymmetric hydrogenation. While noble metal catalysts with chiral tridentate ligands have made significant achievements, there is still a high demand for designing chiral tridentate ligands for earth abundant metal catalysts.

CHEMICAL REVIEWS (2021)

Article Chemistry, Multidisciplinary

Chiral Phosphoric Acid Catalyzed Kinetic Resolution of 2-Amido Benzyl Alcohols: Asymmetric Synthesis of 4H-3,1-Benzoxazines

Subramani Rajkumar et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2020)

Article Chemistry, Multidisciplinary

Lutidine-Based Chiral Pincer Manganese Catalysts for Enantioselective Hydrogenation of Ketones

Linli Zhang et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2019)

Article Pharmacology & Pharmacy

Analgesic and anti-edemic properties of etifoxine in models of inflammatory sensitization

Geraldine Gazzo et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2019)

Article Chemistry, Multidisciplinary

Scope and Mechanism on Iridium-f-Amphamide Catalyzed Asymmetric Hydrogenation of Ketones

Zhiqin Liang et al.

CHINESE JOURNAL OF CHEMISTRY (2018)

Review Chemistry, Inorganic & Nuclear

Coordination determined chemo- and enantioselectivities in asymmetric hydrogenation of multi-functionalized ketones

Xiaomin Xie et al.

COORDINATION CHEMISTRY REVIEWS (2018)

Article Chemistry, Multidisciplinary

Design and Synthesis of Chiral oxa-Spirocyclic Ligands for Ir-Catalyzed Direct Asymmetric Reduction of Bringmann's Lactones with Molecular H2

Gen-Qian Chen et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Article Chemistry, Multidisciplinary

Chiral Cyclohexyl-Fused Spirobiindanes: Practical Synthesis, Ligand Development, and Asymmetric Catalysis

Zhiyao Zheng et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2018)

Review Psychiatry

Anxiolytics targeting GABAA receptors: Insights on etifoxine

Pierrick Poisbeau et al.

WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY (2018)

Article Chemistry, Inorganic & Nuclear

Asymmetric Transfer Hydrogenation of Ketones with Well-Defined Manganese(I) PNN and PNNP Complexes

Karl Z. Demmans et al.

ORGANOMETALLICS (2018)

Article Chemistry, Multidisciplinary

Frustrated Lewis Acid/Bronsted Base Catalysts for Direct Enantioselective α-Amination of Carbonyl Compounds

Ming Shang et al.

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2017)

Review Chemistry, Organic

Recent Advances on Chiral Catalysts for Asymmetric Hydrogenation of C=C, C=N and C=O Bonds

Dario Drommi et al.

CURRENT ORGANIC CHEMISTRY (2016)

Review Chemistry, Medicinal

Efavirenz a nonnucleoside reverse transcriptase inhibitor of first-generation: Approaches based on its medicinal chemistry

Monica M. Bastos et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2016)

Article Chemistry, Organic

Iridium Catalysts with f-Amphox Ligands: Asymmetric Hydrogenation of Simple Ketones

Weilong Wu et al.

ORGANIC LETTERS (2016)

Article Chemistry, Multidisciplinary

An Additional Coordination Group Leads to Extremely Efficient Chiral Iridium Catalysts for Asymmetric Hydrogenation of Ketones

Jian-Hua Xie et al.

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2011)

Review Chemistry, Multidisciplinary

Chiral tertiary diamines in asymmetric synthesis

Jean-Claude Kizirian

CHEMICAL REVIEWS (2008)

Article Multidisciplinary Sciences

Etifoxine improves peripheral nerve regeneration and functional recovery

Christelle Girard et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Chemistry, Organic

Enzyme-catalyzed enantioselective diaryl ketone reductions

Matthew D. Truppo et al.

ORGANIC LETTERS (2007)