Journal
OBESITY SURGERY
Volume 32, Issue 9, Pages 3088-3103Publisher
SPRINGER
DOI: 10.1007/s11695-022-06121-w
Keywords
Vitamin D; Bariatric surgery; Gastric bypass; Sleeve gastrectomy; RYGB; PTH
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Funding
- Isfahan University of Medical Sciences
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Vitamin D supplementation improves vitamin D status in bariatric patients, especially in those taking higher doses and with BMI greater than 50 kg/m(2), and it is also associated with prevention of increasing PTH serum concentration.
Currently, there is no consensus on the optimal vitamin D administration in bariatric patients. The present systematic review and meta-analysis were conducted to examine the effect of vitamin D supplements on serum level of 25(OH) vitamin D in the patients undergoing bariatric surgery (BS). Random model effects were used to estimate standardized mean difference (SMD) with a 95% confidence interval (CI). Nine clinical trials were included in the meta-analysis. Vitamin D supplementation in patients undergoing BS modestly improves vitamin D status (SMD, 0.53; 95% CI, 0.28, 0.77) particularly, in the dosages above 2850 IU/day and in the patients with BMI greater than 50 kg/m(2). Vitamin D supplementation was associated with prevention of raising of the PTH serum concentration and without impact on serum calcium levels.
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