Related references
Note: Only part of the references are listed.Modeling and targeting of erythroleukemia by hematopoietic genome editing
Ilaria Iacobucci et al.
BLOOD (2021)
Histone acetylation dynamics modulates chromatin conformation and allele-specific interactions at oncogenic loci
Stephanie Sungalee et al.
NATURE GENETICS (2021)
CHIPIN: ChIP-seq inter-sample normalization based on signal invariance across transcriptionally constant genes
Lelia Polit et al.
BMC BIOINFORMATICS (2021)
HDAC1 is required for GATA-1 transcription activity, global chromatin occupancy and hematopoiesis
Bowen Yan et al.
NUCLEIC ACIDS RESEARCH (2021)
HDAC1 is required for GATA-1 transcription activity, global chromatin occupancy and hematopoiesis
Bowen Yan et al.
NUCLEIC ACIDS RESEARCH (2021)
Mechanisms governing the pioneering and redistribution capabilities of the non-classical pioneer PU.1
Julia Minderjahn et al.
NATURE COMMUNICATIONS (2020)
Human erythroleukemia genetics and transcriptomes identify master transcription factors as functional disease drivers
Alexandre Fagnan et al.
BLOOD (2020)
Contrasting requirements during disease evolution identify EZH2 as a therapeutic target in AML
Faisal Basheer et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2019)
Safeguard function of PU.1 shapes the inflammatory epigenome of neutrophils
Josephine Fischer et al.
NATURE IMMUNOLOGY (2019)
CHOPCHOP v3: expanding the CRISPR web toolbox beyond genome editing
Kornel Labun et al.
NUCLEIC ACIDS RESEARCH (2019)
A Recurrent Activating Missense Mutation in Waldenstrom Macroglobulinemia Affects the DNA Binding of the ETS Transcription Factor SPI1 and Enhances Proliferation
Damien Roos-Weil et al.
CANCER DISCOVERY (2019)
Structural Features of Transcription Factors Associating with Nucleosome Binding
Meilin Fernandez Garcia et al.
MOLECULAR CELL (2019)
Transcription Factor PU. 1 Represses and Activates Gene Expression in Early T Cells by Redirecting Partner Transcription Factor Binding
Hiroyuki Hosokawa et al.
IMMUNITY (2018)
CRISPOR: intuitive guide selection for CRISPR/Cas9 genome editing experiments and screens
Jean-Paul Concordet et al.
NUCLEIC ACIDS RESEARCH (2018)
A quantitative mass spectrometry-based approach to monitor the dynamics of endogenous chromatin-associated protein complexes
Evangelia K. Papachristou et al.
NATURE COMMUNICATIONS (2018)
RNA cytosine methylation and methyltransferases mediate chromatin organization and 5-azacytidine response and resistance in leukaemia
Jason X. Cheng et al.
NATURE COMMUNICATIONS (2018)
Pioneering, chromatin remodeling, and epigenetic constraint in early T-cell gene regulation by SPIT (PU.1)
Jonas Ungerback et al.
GENOME RESEARCH (2018)
Cistrome Data Browser: a data portal for ChIP-Seq and chromatin accessibility data in human and mouse
Shenglin Mei et al.
NUCLEIC ACIDS RESEARCH (2017)
Recurrent SPI1 (PU.1) fusions in high-risk pediatric T cell acute lymphoblastic leukemia
Masafumi Seki et al.
NATURE GENETICS (2017)
An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues
M. Ryan Corces et al.
NATURE METHODS (2017)
Mechanisms Regulating PRC2 Recruitment and Enzymatic Activity
Daniel Holoch et al.
TRENDS IN BIOCHEMICAL SCIENCES (2017)
Mechanism governing heme synthesis reveals a GATA factor/heme circuit that controls differentiation
Nobuyuki Tanimura et al.
EMBO REPORTS (2016)
Genome-Wide Organization of GATA1 and TAL1 Determined at High Resolution
G. Celine Han et al.
MOLECULAR AND CELLULAR BIOLOGY (2016)
Dynamic Control of Enhancer Repertoires Drives Lineage and Stage-Specific Transcription during Hematopoiesis
Jialiang Huang et al.
DEVELOPMENTAL CELL (2016)
The interaction of PRC2 with RNA or chromatin is mutually antagonistic
Manuel Beltran et al.
GENOME RESEARCH (2016)
Chromatin Remodeler Recruitment during Macrophage Differentiation Facilitates Transcription Factor Binding to Enhancers in Mature Cells
Michael J. McAndrew et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
HDAC inhibitors cause site-specific chromatin remodeling at PU.1-bound enhancers in K562 cells
Christopher L. Frank et al.
EPIGENETICS & CHROMATIN (2016)
Non-canonical PRC1.1 Targets Active Genes Independent of H3K27me3 and Is Essential for Leukemogenesis
Vincent van den Boom et al.
CELL REPORTS (2016)
Tet2 and Tet3 cooperate with B-lineage transcription factors to regulate DNA modification and chromatin accessibility
Chan-Wang Lio et al.
ELIFE (2016)
Functionally Relevant RNA Helicase Mutations in Familial and Sporadic Myeloid Malignancies
Ileana Antony-Debre et al.
CANCER CELL (2015)
Searching for Drug Synergy in Complex Dose-Response Landscapes Using an Interaction Potency Model
Bhagwan Yadav et al.
COMPUTATIONAL AND STRUCTURAL BIOTECHNOLOGY JOURNAL (2015)
Runx1 Regulation of Pu.1 Corepressor/Coactivator Exchange Identifies Specific Molecular Targets for Leukemia Differentiation Therapy
Xiaorong Gu et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
Coregulation of Transcription Factor Binding and Nucleosome Occupancy through DNA Features of Mammalian Enhancers
Iros Barozzi et al.
MOLECULAR CELL (2014)
PU.1 is essential for MLL leukemia partially via crosstalk with the MEIS/HOX pathway
J. Zhou et al.
LEUKEMIA (2014)
A comparative encyclopedia of DNA elements in the mouse genome
Feng Yue et al.
NATURE (2014)
BRD4 assists elongation of both coding and enhancer RNAs by interacting with acetylated histones
Tomohiko Kanno et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
Nucleosomes Are Stably Evicted from Enhancers but Not Promoters upon Induction of Certain Pro-Inflammatory Genes in Mouse Macrophages
Alison Gjidoda et al.
PLOS ONE (2014)
Chromatin state dynamics during blood formation
David Lara-Astiaso et al.
SCIENCE (2014)
STAR: ultrafast universal RNA-seq aligner
Alexander Dobin et al.
BIOINFORMATICS (2013)
HMCan: a method for detecting chromatin modifications in cancer samples using ChIP-seq data
Haitham Ashoor et al.
BIOINFORMATICS (2013)
Epigenetic silencing of Bim transcription by Spi-1/PU.1 promotes apoptosis resistance in leukaemia
M. Ridinger-Saison et al.
CELL DEATH AND DIFFERENTIATION (2013)
Promiscuous RNA binding by Polycomb repressive complex 2
Chen Davidovich et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
PRC2 binds active promoters and contacts nascent RNAs in embryonic stem cells
Syuzo Kaneko et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
Timothy J. Ley et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
Mechanisms of in vivo binding site selection of the hematopoietic master transcription factor PU.1
Thu-Hang Pham et al.
NUCLEIC ACIDS RESEARCH (2013)
PU.1 target genes undergo Tet2-coupled demethylation and DNMT3b-mediated methylation in monocyte-to-osteoclast differentiation
Lorenzo de la Rica et al.
GENOME BIOLOGY (2013)
Ezh2 augments leukemogenicity by reinforcing differentiation blockage in acute myeloid leukemia
Satomi Tanaka et al.
BLOOD (2012)
Histone Recognition and Large-Scale Structural Analysis of the Human Bromodomain Family
Panagis Filippakopoulos et al.
CELL (2012)
Acetylation of Histone Deacetylase 1 Regulates NuRD Corepressor Complex Activity
Tao Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Spi-1/PU.1 activates transcription through clustered DNA occupancy in erythroleukemia
Maya Ridinger-Saison et al.
NUCLEIC ACIDS RESEARCH (2012)
Polycomb repressive complex 2 is required for MLL-AF9 leukemia
Tobias Neff et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
A core erythroid transcriptional network is repressed by a master regulator of myelo-lymphoid differentiation
Sandeep N. Wontakal et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2012)
Roles of histone deacetylases in epigenetic regulation: emerging paradigms from studies with inhibitors
Genevieve P. Delcuve et al.
CLINICAL EPIGENETICS (2012)
Dynamics of the epigenetic landscape during erythroid differentiation after GATA1 restoration
Weisheng Wu et al.
GENOME RESEARCH (2011)
ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity
Matthew D. Young et al.
NUCLEIC ACIDS RESEARCH (2011)
A Large Gene Network in Immature Erythroid Cells Is Controlled by the Myeloid and B Cell Transcriptional Regulator PU.1
Sandeep N. Wontakal et al.
PLOS GENETICS (2011)
The genome-wide dynamics of the binding of Ldb1 complexes during erythroid differentiation
Eric Soler et al.
GENES & DEVELOPMENT (2010)
Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages
Serena Ghisletti et al.
IMMUNITY (2010)
Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities
Sven Heinz et al.
MOLECULAR CELL (2010)
PU.1-mediated upregulation of CSF1R is crucial for leukemia stem cell potential induced by MOZ-TIF2
Yukiko Aikawa et al.
NATURE MEDICINE (2010)
Fast and accurate short read alignment with Burrows-Wheeler transform
Heng Li et al.
BIOINFORMATICS (2009)
Erythroid GATA1 function revealed by genome-wide analysis of transcription factor occupancy, histone modifications, and mRNA expression
Yong Cheng et al.
GENOME RESEARCH (2009)
Dose-dependent repression of T-cell and natural killer cell genes by PU.1 enforces myeloid and B-cell identity
M. B. Kamath et al.
LEUKEMIA (2008)
Combinatorial patterns of histone acetylations and methylations in the human genome
Zhibin Wang et al.
NATURE GENETICS (2008)
High-resolution profiling of histone methylations in the human genome
Artern Barski et al.
CELL (2007)
Spi-1/PU.1 participates in erythroleukemogenesis by inhibiting apoptosis in cooperation with Epo signaling and by blocking erythroid differentiation
Pauline Rimmele et al.
BLOOD (2007)
Acetylation of GATA-1 is required for chromatin occupancy
Janine M. Lamonica et al.
BLOOD (2006)
Lymphoid cell growth and transformation are suppressed by a key regulatory element of the gene encoding PU.1
F Rosenbauer et al.
NATURE GENETICS (2006)
PU.1 inhibits the erythroid program by binding to GATA-1 on DNA and creating a repressive chromatin structure
T Stopka et al.
EMBO JOURNAL (2005)
The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription
MK Jang et al.
MOLECULAR CELL (2005)
Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein brd4
ZY Yang et al.
MOLECULAR CELL (2005)
Dynamic regulation of PU.1 expression in multipotent hematopoietic progenitors
SL Nutt et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2005)
Selective recognition of acetylated histones by bromodomain proteins visualized in living cells
T Kanno et al.
MOLECULAR CELL (2004)
Multiple functional domains of the oncoproteins Spi-1/PU.1 and TLS are involved in their opposite splicing effects in erythroleukemic cells
L Delva et al.
ONCOGENE (2004)
PU.1 determines the self-renewal capacity of erythroid progenitor cells
J Back et al.
BLOOD (2004)
The double bromodomain protein Brd4 binds to acetylated chromatin during interphase and mitosis
A Dey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
PU.1 and pRB interact and cooperate to repress GATA-1 and block erythroid differentiation
N Rekhtman et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
Histone methyltransferase activity associated with a human multiprotein complex containing the Enhancer of Zeste protein
A Kuzmichev et al.
GENES & DEVELOPMENT (2002)
Role of histone H3 lysine 27 methylation in polycomb-group silencing
R Cao et al.
SCIENCE (2002)
Inhibition of CBP-mediated protein acetylation by the Ets family oncoprotein PU.1
W Hong et al.
MOLECULAR AND CELLULAR BIOLOGY (2002)
In vivo complex formation of PU.1 with HDAC1 associated with PU.1-mediated transcriptional repression
F Kihara-Negishi et al.
ONCOGENE (2001)
Proteins of the ETS family with transcriptional repressor activity
G Mavrothalassitis et al.
ONCOGENE (2000)