Journal
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
Volume 141, Issue -, Pages -Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.neubiorev.2022.104818
Keywords
Keywords; Endoplasmic reticulum stress; Natural products; Neurological disorders; Neurodegenerative diseases; Neuroprotection; Neuroprotective agents; Alzheimer ?s disease; Parkinson ?s disease
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The primary aim of this review is to summarize the literature on natural products that target endoplasmic reticulum stress (ERS) for the treatment of various neurological disorders. ERS has been implicated in the pathogenesis of multiple neurological disorders, and several natural products targeting ERS signaling pathways have potential neuroprotective properties.
The primary aim of this review is to summarize the literature on natural products that are effective in the treatment of various neurological disorders by targeting endoplasmic reticulum stress (ERS). Various electronic databases such as SCOPUS, PubMed, Web of Science, and Google Scholar were searched for relevant publica-tions. ERS has been implicated in the pathogenesis of numerous neurological disorders such as cerebral ischemia, Parkinson's disease, and Alzheimer's disease. Several natural products targeting ERS signalling pathways provide therapeutic options for neurological diseases, and in this review, the potential neuroprotective properties of these products are discussed.
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