4.5 Article

Loureirin C and Xanthoceraside Attenuate Depression-Like Behaviors and Expression of Interleukin-17 in the Prefrontal Cortex Induced by Chronic Unpredictable Mild Stress in Mice

Related references

Note: Only part of the references are listed.
Article Behavioral Sciences

miR-182 mediated the inhibitory effects of NF-κB on the GPR39/CREB/BDNF pathway in the hippocampus of mice with depressive-like behaviors

Yuxiao Tang et al.

Summary: The study found that activation of NF-kappa B inhibited the GPR39/CREB/BDNF pathway by increasing miR-182 in chronic stress-induced depressive-like behaviors. The negative-regulation features of miRNAs may play an important role in the inhibition of neurofunction induced by neuroinflammation in depression.

BEHAVIOURAL BRAIN RESEARCH (2022)

Article Biochemistry & Molecular Biology

Prefrontal cortex miR-874-3p prevents lipopolysaccharide-induced depression-like behavior through inhibition of indoleamine 2,3-dioxygenase 1 expression in mice

Willy Jaya Suento et al.

Summary: In this study, it was found that miR-874-3p may play an important role in preventing LPS-induced depression-like behavior through inhibition of IDO1 expression, which could potentially serve as a novel target for the treatment of MDD.

JOURNAL OF NEUROCHEMISTRY (2021)

Article Behavioral Sciences

Kynurenine 3-monooxygenase deficiency induces depression-like behavior via enhanced antagonism of α7 nicotinic acetylcholine receptors by kynurenic acid

Yuko Mori et al.

Summary: The study revealed that the levels of KYN, KA, and anthranilic acid were elevated in the prefrontal cortex of KMO KO mice, along with increased mRNA levels of KAT1 and alpha 7nAChR. Nicotine and galantamine were able to ameliorate depression-like behaviors in KMO KO mice by activating alpha 7nAChR.

BEHAVIOURAL BRAIN RESEARCH (2021)

Article Cell Biology

IL-17 triggers the onset of cognitive and synaptic deficits in early stages of Alzheimer's disease

Helena C. Brigas et al.

Summary: The study found that in Alzheimer's disease models, there is an accumulation of interleukin 17-producing cells in the brain and meninges of female mice, which is associated with cognitive decline. Additionally, neutralization of interleukin 17 can prevent early memory and synaptic plasticity deficits, suggesting an early involvement of interleukin 17 in Alzheimer's disease pathology.

CELL REPORTS (2021)

Article Integrative & Complementary Medicine

Dragon's Blood from Dracaena Worldwide: Species, Traditional Uses, Phytochemistry and Pharmacology

Yang Liu et al.

Summary: Dragon's blood is a crimson resin from Dracaena spp. that has been used in traditional medicines worldwide for over 1000 years. It is known for its various therapeutic properties and compounds. However, due to limited resources and unclear resin formation mechanism, there is a need to expand cultivation and develop effective methods for sustainable utilization.

AMERICAN JOURNAL OF CHINESE MEDICINE (2021)

Review Behavioral Sciences

New insights on the role of the retina in diagnostic and therapeutic strategies in major depressive disorder

Eve Cosker et al.

NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2020)

Review Immunology

Priming Microglia for Innate Immune Memory in the Brain

Jonas J. Neher et al.

TRENDS IN IMMUNOLOGY (2019)

Article Psychology, Clinical

Metabolic and inflammatory markers: associations with individual depressive symptoms

F. Lamers et al.

PSYCHOLOGICAL MEDICINE (2018)

Article Immunology

Depression and sterile inflammation: Essential role of danger associated molecular patterns

Tina C. Franklin et al.

BRAIN BEHAVIOR AND IMMUNITY (2018)

Review Cell Biology

Neuropeptides and Microglial Activation in Inflammation, Pain, and Neurodegenerative Diseases

Lila Carniglia et al.

MEDIATORS OF INFLAMMATION (2017)

Review Immunology

IL-17 Signaling: The Yin and the Yang

Nilesh Amatya et al.

TRENDS IN IMMUNOLOGY (2017)

Review Neurosciences

Integrating neuroimmune systems in the neurobiology of depression

Eric S. Wohleb et al.

NATURE REVIEWS NEUROSCIENCE (2016)

Review Neurosciences

Neuroimmune mechanisms of depression

Georgia E. Hodes et al.

NATURE NEUROSCIENCE (2015)

Article Biology

Dragon's blood and its extracts attenuate radiation-induced oxidative stress in mice

Yuanyuan Ran et al.

JOURNAL OF RADIATION RESEARCH (2014)

Review Neurosciences

Neural Mechanisms of Stress Resilience and Vulnerability

Tamara B. Franklin et al.

NEURON (2012)

Article Critical Care Medicine

Cyclooxygenase-2 Regulates Th17 Cell Differentiation during Allergic Lung Inflammation

Hong Li et al.

AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2011)

Article Biochemistry & Molecular Biology

Altered expression of genes involved in inflammation and apoptosis in frontal cortex in major depression

R. C. Shelton et al.

MOLECULAR PSYCHIATRY (2011)

Article Plant Sciences

Protective effects of xanthoceraside on learning and memory impairment induced by A beta(25-35) in mice

Tian-Yan Chi et al.

JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH (2009)

Article Biochemistry & Molecular Biology

Pivotal role of cerebral interleukin-17-producing γδT cells in the delayed phase of ischemic brain injury

Takashi Shichita et al.

NATURE MEDICINE (2009)

Review Plant Sciences

Dragon's blood: Botany, chemistry and therapeutic uses

Deepika Gupta et al.

JOURNAL OF ETHNOPHARMACOLOGY (2008)

Article Biochemistry & Molecular Biology

Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation

Hania Kebir et al.

NATURE MEDICINE (2007)

Article Multidisciplinary Sciences

IL-6-dependent and -independent pathways in the development of interleukin 17-producing T helper cells

Akihiro Kimura et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)

Article Plant Sciences

Two new triterpenes from the husks of Xanthoceras sorbifolia

ZL Li et al.

PLANTA MEDICA (2005)

Review Biotechnology & Applied Microbiology

The ascent of mouse: Advances in modelling human depression and anxiety

JF Cryan et al.

NATURE REVIEWS DRUG DISCOVERY (2005)

Article Medicine, General & Internal

The epidemiology of major depressive disorder - Results from the National Comorbidity Survey Replication (NCS-R).

RC Kessler et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2003)