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Article
Engineering, Biomedical
A multi-organ chip with matured tissue niches linked by vascular flow
Kacey Ronaldson-Bouchard et al.
Summary: This study reports the development and application of a tissue-chip system where matured human heart, liver, bone, and skin tissue niches are interconnected by recirculating vascular flow, allowing for the replication of interdependent organ functions and potentially enhancing clinical applicability.
NATURE BIOMEDICAL ENGINEERING (2022)