Related references
Note: Only part of the references are listed.Increased somatic mutation burdens in normal human cells due to defective DNA polymerases
Philip S. Robinson et al.
NATURE GENETICS (2021)
A systematic CRISPR screen defines mutational mechanisms underpinning signatures caused by replication errors and endogenous DNA damage
Xueqing Zou et al.
NATURE CANCER (2021)
Tobacco smoking and somatic mutations in human bronchial epithelium
Kenichi Yoshida et al.
NATURE (2020)
Recurrent Genetic Abnormalities in Human Pluripotent Stem Cells: Definition and Routine Detection in Culture Supernatant by Targeted Droplet Digital PCR
Said Assou et al.
STEM CELL REPORTS (2020)
The mutational impact of culturing human pluripotent and adult stem cells
Ewart Kuijk et al.
NATURE COMMUNICATIONS (2020)
Low rates of mutation in clinical grade human pluripotent stem cells under different culture conditions
Oliver Thompson et al.
NATURE COMMUNICATIONS (2020)
The mutational landscape of normal human endometrial epithelium
Luiza Moore et al.
NATURE (2020)
Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes
Davis J. McCarthy et al.
NATURE METHODS (2020)
A practical framework and online tool for mutational signature analyses show intertissue variation and driver dependencies
Andrea Degasperi et al.
NATURE CANCER (2020)
Induced pluripotent stem cells in disease modelling and drug discovery
R. Grant Rowe et al.
NATURE REVIEWS GENETICS (2019)
A Compendium of Mutational Signatures of Environmental Agents
Jill E. Kucab et al.
CELL (2019)
The landscape of somatic mutation in normal colorectal epithelial cells
Henry Lee-Six et al.
NATURE (2019)
Clonal hematopoiesis in human aging and disease
Siddhartha Jaiswal et al.
SCIENCE (2019)
DNMT3A mutation is associated with increased age and adverse outcome in adult T-cell acute lymphoblastic leukemia
Jonathan Bond et al.
HAEMATOLOGICA (2019)
Characterising Mutational Spectra of Carcinogens in the Tumour Suppressor Gene TP53 Using Human TP53 Knock-in (Hupki) Mouse Embryo Fibroblasts
Lisa Hoelzl-Armstrong et al.
METHODS AND PROTOCOLS (2019)
A Non-canonical BCOR-PRC1.1 Complex Represses Differentiation Programs in Human ESCs
Zheng Wang et al.
CELL STEM CELL (2018)
Quantification of subclonal selection in cancer from bulk sequencing data
Marc J. Williams et al.
NATURE GENETICS (2018)
Validating the concept of mutational signatures with isogenic cell models
Xueqing Zou et al.
NATURE COMMUNICATIONS (2018)
Reprogrammed stem cells approved to mend hearts
David Cyranoski
NATURE (2018)
Insights into the Mutational Burden of Human Induced Pluripotent Stem Cells from an Integrative Multi-Omics Approach
Matteo D'Antonio et al.
CELL REPORTS (2018)
Somatic mutant clones colonize the human esophagus with age
Inigo Martincorena et al.
SCIENCE (2018)
Influence of donor age on induced pluripotent stem cells
Valentina Lo Sardo et al.
NATURE BIOTECHNOLOGY (2017)
Induced pluripotent stem cell technology: a decade of progress
Yanhong Shi et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
Common genetic variation drives molecular heterogeneity in human iPSCs
Helena Kilpinen et al.
NATURE (2017)
Human pluripotent stem cells recurrently acquire and expand dominant negative P53 mutations
Florian T. Merkle et al.
NATURE (2017)
Autologous Induced Stem-Cell-Derived Retinal Cells for Macular Degeneration
M. Mandai et al.
NEW ENGLAND JOURNAL OF MEDICINE (2017)
iPSCs and fibroblast subclones from the same fibroblast population contain comparable levels of sequence variations
Erika M. Kwon et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer
Jarno Drost et al.
SCIENCE (2017)
AACR Project GENIE: Powering Precision Medicine through an International Consortium
Fabrice Andre et al.
CANCER DISCOVERY (2017)
Hotspots of De Novo Point Mutations in Induced Pluripotent Stem Cells
Masahito Yoshihara et al.
CELL REPORTS (2017)
Universal Patterns of Selection in Cancer and Somatic Tissues
Inigo Martincorena et al.
CELL (2017)
BCFtools/csq: haplotype-aware variant consequences
Petr Danecek et al.
BIOINFORMATICS (2017)
Nucleotide excision repair is impaired by binding of transcription factors to DNA
Radhakrishnan Sabarinathan et al.
NATURE (2016)
Differential DNA repair underlies mutation hotspots at active promoters in cancer genomes
Dilmi Perera et al.
NATURE (2016)
Tissue-specific mutation accumulation in human adult stem cells during life
Francis Blokzijl et al.
NATURE (2016)
Analysis of protein-coding genetic variation in 60,706 humans
Monkol Lek et al.
NATURE (2016)
Whole-genome mutational burden analysis of three pluripotency induction methods
Kunal Bhutani et al.
NATURE COMMUNICATIONS (2016)
The Impact of Environmental and Endogenous Damage on Somatic Mutation Load in Human Skin Fibroblasts
Natalie Saini et al.
PLOS GENETICS (2016)
Mutational History of a Human Cell Lineage from Somatic to Induced Pluripotent Stem Cells
Foad J. Rouhani et al.
PLOS GENETICS (2016)
Detecting Genetic Mosaicism in Cultures of Human Pluripotent Stem Cells
Duncan Baker et al.
STEM CELL REPORTS (2016)
The Ensembl Variant Effect Predictor
William McLaren et al.
GENOME BIOLOGY (2016)
Cell-of-origin chromatin organization shapes the mutational landscape of cancer
Paz Polak et al.
NATURE (2015)
High burden and pervasive positive selection of somatic mutations in normal human skin
Inigo Martincorena et al.
SCIENCE (2015)
Successful Generation of Human Induced Pluripotent Stem Cell Lines from Blood Samples Held at Room Temperature for up to 48 hr
Chukwuma A. Agu et al.
STEM CELL REPORTS (2015)
Increased Risk of Genetic and Epigenetic Instability in Human Embryonic Stem Cells Associated with Specific Culture Conditions
Ibon Garitaonandia et al.
PLOS ONE (2015)
featureCounts: an efficient general purpose program for assigning sequence reads to genomic features
Yang Liao et al.
BIOINFORMATICS (2014)
Gain of 20q11.21 in human embryonic stem cells improves cell survival by increased expression of Bcl-xL
H. T. Nguyen et al.
MOLECULAR HUMAN REPRODUCTION (2014)
Age-related mutations associated with clonal hematopoietic expansion and malignancies
Mingchao Xie et al.
NATURE MEDICINE (2014)
Clonal Hematopoiesis and Blood-Cancer Risk Inferred from Blood DNA Sequence
Giulio Genovese et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Age-Related Clonal Hematopoiesis Associated with Adverse Outcomes
Siddhartha Jaiswal et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Genetic Background Drives Transcriptional Variation in Human Induced Pluripotent Stem Cells
Foad Rouhani et al.
PLOS GENETICS (2014)
Efficient and Cost-Effective Generation of Mature Neurons From Human Induced Pluripotent Stem Cells
Cherif Badja et al.
STEM CELLS TRANSLATIONAL MEDICINE (2014)
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
Michael I. Love et al.
GENOME BIOLOGY (2014)
STAR: ultrafast universal RNA-seq aligner
Alexander Dobin et al.
BIOINFORMATICS (2013)
BCOR and BCORL1 mutations in myelodysplastic syndromes and related disorders
Frederik Damm et al.
BLOOD (2013)
Genomic and Epigenomic Landscapes of Adult De Novo Acute Myeloid Leukemia
Timothy J. Ley et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
BCL-XL Mediates the Strong Selective Advantage of a 20q11.21 Amplification Commonly Found in Human Embryonic Stem Cell Cultures
Stuart Avery et al.
STEM CELL REPORTS (2013)
Background Mutations in Parental Cells Account for Most of the Genetic Heterogeneity of Induced Pluripotent Stem Cells
Margaret A. Young et al.
CELL STEM CELL (2012)
Somatic copy number mosaicism in human skin revealed by induced pluripotent stem cells
Alexej Abyzov et al.
NATURE (2012)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham et al.
NATURE (2012)
An integrated map of genetic variation from 1,092 human genomes
David M. Altshuler et al.
NATURE (2012)
Elevated Coding Mutation Rate During the Reprogramming of Human Somatic Cells into Induced Pluripotent Stem Cells
Junfeng Ji et al.
STEM CELLS (2012)
Whole-exome sequencing identifies somatic mutations of BCOR in acute myeloid leukemia with normal karyotype
Vera Grossmann et al.
BLOOD (2011)
Dynamic Changes in the Copy Number of Pluripotency and Cell Proliferation Genes in Human ESCs and iPSCs during Reprogramming and Time in Culture
Louise C. Laurent et al.
CELL STEM CELL (2011)
Somatic coding mutations in human induced pluripotent stem cells
Athurva Gore et al.
NATURE (2011)
Copy number variation and selection during reprogramming to pluripotency
Samer M. Hussein et al.
NATURE (2011)
Karotypic abnormalities in human induced pluripotent stem cells and embryonic stem cells
Seth M. Taapken et al.
NATURE BIOTECHNOLOGY (2011)
Recurrent copy number variations in human induced pluripotent stem cells
Kristen Martins-Taylor et al.
NATURE BIOTECHNOLOGY (2011)
Screening ethnically diverse human embryonic stem cells identifies a chromosome 20 minimal amplicon conferring growth advantage
Katherine Amps et al.
NATURE BIOTECHNOLOGY (2011)
Fast and accurate long-read alignment with Burrows-Wheeler transform
Heng Li et al.
BIOINFORMATICS (2010)
Identification and Classification of Chromosomal Aberrations in Human Induced Pluripotent Stem Cells
Yoav Mayshar et al.
CELL STEM CELL (2010)
The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data
Aaron McKenna et al.
GENOME RESEARCH (2010)
Adaptation to culture of human embryonic stem cells and oncogenesis in vivo
Duncan E. C. Baker et al.
NATURE BIOTECHNOLOGY (2007)
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
Kazutoshi Takahashi et al.
CELL (2006)
UV radiation exposure related to age, sex, occupation, and sun Behavior based on time-stamped personal dosimeter readings
E Thieden et al.
ARCHIVES OF DERMATOLOGY (2004)
Recurrent gain of chromosomes 17q and 12 in cultured human embryonic stem cells
JS Draper et al.
NATURE BIOTECHNOLOGY (2004)
Structural basis for recognition and repair of the endogenous mutagen 8-oxoguanine in DNA
SD Bruner et al.
NATURE (2000)