Related references
Note: Only part of the references are listed.Insoluble tau aggregates induce neuronal death through modification of membrane ion conductance, activation of voltage-gated calcium channels and NADPH oxidase
Noemi Esteras et al.
FEBS JOURNAL (2021)
Physicochemical Stability of Monoclonal Antibodies: A Review
Yoann Le Basle et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2020)
Dimerization of α-Conotoxins as a Strategy to Enhance the Inhibition of the Human α7 and α9α10 Nicotinic Acetylcholine Receptors
Jiazhen Liang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2020)
A simple, versatile and robust centrifugation-based filtration protocol for the isolation and quantification of α-synuclein monomers, oligomers and fibrils: Towards improving experimental reproducibility in α-synuclein research
Senthil T. Kumar et al.
JOURNAL OF NEUROCHEMISTRY (2020)
The α-synuclein hereditary mutation E46K unlocks a more stable, pathogenic fibril structure
David R. Boyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Design of a multivalent bifunctional chelator for diagnostic 64Cu PET imaging in Alzheimer's disease
Hong-Jun Cho et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
Antibodies against alpha-synuclein: tools and therapies
Nishant N. Vaikath et al.
JOURNAL OF NEUROCHEMISTRY (2019)
Mass Spectrometric Analysis of Lewy Body-Enriched α-Synuclein in Parkinson's Disease
Payel Bhattacharjee et al.
JOURNAL OF PROTEOME RESEARCH (2019)
Different soluble aggregates of Aβ42 can give rise to cellular toxicity through different mechanisms
Suman De et al.
NATURE COMMUNICATIONS (2019)
Soluble aggregates present in cerebrospinal fluid change in size and mechanism of toxicity during Alzheimer's disease progression
Suman De et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2019)
Proximity labeling of protein complexes and cell-type-specific organellar proteomes in Arabidopsis enabled by TurboID
Andrea Mair et al.
ELIFE (2019)
Quantitative proteomics reveals distinct composition of amyloid plaques in Alzheimer's disease
Feng Xiong et al.
ALZHEIMERS & DEMENTIA (2019)
Conservation of the Amyloid Interactome Across Diverse Fibrillar Structures
Dennis Wilkens Juhl et al.
SCIENTIFIC REPORTS (2019)
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions
Benedetta Mannini et al.
ACS CHEMICAL NEUROSCIENCE (2018)
Optical Structural Analysis of Individual α-Synuclein Oligomers
Juan A. Varela et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2018)
Aptamers Selected for Recognizing Amyloid beta-Protein-A Case for Cautious Optimism
Farid Rahimi
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
RFAmyloid: A Web Server for Predicting Amyloid Proteins
Mengting Niu et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Structural heterogeneity and intersubject variability of A beta in familial and sporadic Alzheimer's disease
Carlo Condello et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease
Marthe H. R. Ludtmann et al.
NATURE COMMUNICATIONS (2018)
Single-Molecule Characterization of the Interactions between Extracellular Chaperones and Toxic α-Synuclein Oligomers
Daniel R. Whiten et al.
CELL REPORTS (2018)
Investigation of alpha-Synuclein Amyloid Fibrils Using the Fluorescent Probe Thioflavin T
Anna I. Sulatskaya et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Protein Co-Aggregation Related to Amyloids: Methods of Investigation, Diversity, and Classification
Stanislav A. Bondarev et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Protein misfolding, aggregation, and conformational strains in neurodegenerative diseases
Claudio Soto et al.
NATURE NEUROSCIENCE (2018)
A new era for understanding amyloid structures and disease
Matthew G. Iadanza et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2018)
Mapping Surface Hydrophobicity of α-Synuclein Oligomers at the Nanoscale
Ji-Eun Lee et al.
NANO LETTERS (2018)
Investigating the Degradation Behaviors of a Therapeutic Monoclonal Antibody Associated with pH and Buffer Species
Songyan Zheng et al.
AAPS PHARMSCITECH (2017)
Tau Oligomers in Sera of Patients with Alzheimer's Disease and Aged Controls
Michala Kolarova et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Structural basis of membrane disruption and cellular toxicity by α-synuclein oligomers
Giuliana Fusco et al.
SCIENCE (2017)
Phosphorylated exogenous alpha-synuclein fibrils exacerbate pathology and induce neuronal dysfunction in mice
Mantia Karampetsou et al.
SCIENTIFIC REPORTS (2017)
Inhibiting the Ca2+ Influx Induced by Human CSF
Anna Drews et al.
CELL REPORTS (2017)
Tau oligomers in cerebrospinal fluid in Alzheimer's disease
Urmi Sengupta et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2017)
Ultrasensitive Measurement of Ca2+ Influx into Lipid Vesicles Induced by Protein Aggregates
Patrick Flagmeier et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2017)
Single-Molecule Imaging of Individual Amyloid Protein Aggregates in Human Biofluids
Mathew H. Horrocks et al.
ACS CHEMICAL NEUROSCIENCE (2016)
Methods for the Specific Detection and Quantitation of Amyloid-beta Oligomers in Cerebrospinal Fluid
Judith Schuster et al.
JOURNAL OF ALZHEIMERS DISEASE (2016)
Kinetic model of the aggregation of alpha-synuclein provides insights into prion-like spreading
Marija Iljina et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2016)
Development of a quantitative fluorescence-based ligand-binding assay
Conor J. Breen et al.
SCIENTIFIC REPORTS (2016)
Identification of novel CSF biomarkers for neurodegeneration and their validation by a high-throughput multiplexed targeted proteomic assay
Wendy E. Heywood et al.
MOLECULAR NEURODEGENERATION (2015)
Alzheimer's and Parkinson's diseases: The prion concept in relation to assembled Aβ, tau, and α-synuclein
Michel Goedert
SCIENCE (2015)
Single-molecule FRET studies on alpha-synuclein oligomerization of Parkinson's disease genetically related mutants
Laura Tosatto et al.
SCIENTIFIC REPORTS (2015)
Titration of biologically active amyloid-beta seeds in a transgenic mouse model of Alzheimer's disease
Rodrigo Morales et al.
SCIENTIFIC REPORTS (2015)
Efficient isolation and elution of cellular proteins using aptamer-mediated protein precipitation assay
Kiseok Kim et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2014)
Linker Length Matters, Fynomer-Fc Fusion with an Optimized Linker Displaying Picomolar IL-17A Inhibition Potency
Michela Silacci et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2014)
A Sensitive Aβ Oligomer Assay Discriminates Alzheimer's and Aged Control Cerebrospinal Fluid
Mary J. Savage et al.
JOURNAL OF NEUROSCIENCE (2014)
In-depth Characterization of the Cerebrospinal Fluid (CSF) Proteome Displayed Through the CSF Proteome Resource (CSF-PR)
Astrid Guldbrandsen et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
The amyloid state and its association with protein misfolding diseases
Tuomas P. J. Knowles et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
PASTA 2.0: an improved server for protein aggregation prediction
Ian Walsh et al.
NUCLEIC ACIDS RESEARCH (2014)
Aggregate-Depleted Brain Fails to Induce Aβ Deposition in a Mouse Model of Alzheimer's Disease
Claudia Duran-Aniotz et al.
PLOS ONE (2014)
Chemical kinetics for drug discovery to combat protein aggregation diseases
Paolo Arosio et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2014)
Levels of cerebrospinal fluid α-synuclein oligomers are increased in Parkinson's disease with dementia and dementia with Lewy bodies compared to Alzheimer's disease
Oskar Hansson et al.
ALZHEIMERS RESEARCH & THERAPY (2014)
Systematic Comparison of the Effects of Alpha-synuclein Mutations on Its Oligomerization and Aggregation
Diana F. Lazaro et al.
PLOS GENETICS (2014)
Direct Observation of the Interconversion of Normal and Toxic Forms of α-Synuclein
Nunilo Cremades et al.
CELL (2012)
Methods for Analysis of Amyloid-β Aggregates
Kim A. Bruggink et al.
JOURNAL OF ALZHEIMERS DISEASE (2012)
Intracerebral inoculation of pathological α-synuclein initiates a rapidly progressive neurodegenerative α-synucleinopathy in mice
Kelvin C. Luk et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
DNA aptamers detecting generic amyloid epitopes
Olga V. Mitkevich et al.
PRION (2012)
On the Origin of the Stronger Binding of PIB over Thioflavin T to Protofibrils of the Alzheimer Amyloid-β Peptide: A Molecular Dynamics Study
Chun Wu et al.
BIOPHYSICAL JOURNAL (2011)
α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study (vol 10, pg 230, 2011)
B. Mollenhauer et al.
LANCET NEUROLOGY (2011)
Antibody cross-linking and target elution protocols used for immunoprecipitation significantly modulate signal-to noise ratio in downstream 2D-PAGE analysis
Mirta M. L. Sousa et al.
PROTEOME SCIENCE (2011)
α-Synuclein and tau concentrations in cerebrospinal fluid of patients presenting with parkinsonism: a cohort study
Brit Mollenhauer et al.
LANCET NEUROLOGY (2011)
Molecular Modeling and Affinity Determination of scFv Antibody: Proper Linker Peptide Enhances Its Activity
Xin Gu et al.
ANNALS OF BIOMEDICAL ENGINEERING (2010)
Molecular mechanism of Thioflavin-T binding to amyloid fibrils
Matthew Biancalana et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2010)
Highly sensitive amyloid detection enabled by thioflavin T dimers
Luoheng Qin et al.
MOLECULAR BIOSYSTEMS (2010)
Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis
Yvonne S. Eisele et al.
SCIENCE (2010)
In vitro high affinity α-synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain
Liang Ye et al.
JOURNAL OF NEUROCHEMISTRY (2008)
Formation of Toxic Oligomeric α-Synuclein Species in Living Cells
Tiago Fleming Outeiro et al.
PLOS ONE (2008)
Antibody structure, instability, and formulation
Wei Wang et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2007)
Exogenous induction of cerebral β-amyloidogenesis is governed by agent and host
Melanie Meyer-Luehmann et al.
SCIENCE (2006)
[11]PIB in a nondemented population -: Potential antecedent marker of Alzheimer disease
M. A. Mintun et al.
NEUROLOGY (2006)
Imaging brain amyloid in Alzheimer's disease with Pittsburgh Compound-B
WE Klunk et al.
ANNALS OF NEUROLOGY (2004)
Dependence of α-synuclein aggregate morphology on solution conditions
W Hoyer et al.
JOURNAL OF MOLECULAR BIOLOGY (2002)
Uncharged thioflavin-T derivatives bind to amyloid-beta protein with high affinity and readily enter the brain
WE Klunk et al.
LIFE SCIENCES (2001)
An analytical approach to the measurement of equilibrium binding constants: Application to EGF binding to EGF receptors in intact cells measured by flow cytometry
RA Stein et al.
BIOCHEMISTRY (2001)