Journal
NATURE CHEMICAL BIOLOGY
Volume 18, Issue 9, Pages 918-920Publisher
NATURE PORTFOLIO
DOI: 10.1038/s41589-022-01020-8
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A directed evolution approach can generate ribosomes with highly functional tethered subunits, integrating the decoding and peptidyl transferase activities of the ribosome into a single entity, potentially leading to more efficient protein engineering technologies.
A directed evolution approach delivers ribosomes with highly functional tethered subunits. Combining the decoding and peptidyl transferase activities of the ribosome into a single entity sets the scene for more efficient protein engineering technologies.
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