Related references
Note: Only part of the references are listed.HLA-independent T cell receptors for targeting tumors with low antigen density
Jorge Mansilla-Soto et al.
NATURE MEDICINE (2022)
Promoterless, Nuclease-Free Genome Editing Confers a Growth Advantage for Corrected Hepatocytes in Mice With Methylmalonic Acidemia
Randy J. Chandler et al.
HEPATOLOGY (2021)
Whole chromosome loss and genomic instability in mouse embryos after CRISPR-Cas9 genome editing
Stamatis Papathanasiou et al.
NATURE COMMUNICATIONS (2021)
Chromothripsis as an on-target consequence of CRISPR-Cas9 genome editing
Mitchell L. Leibowitz et al.
NATURE GENETICS (2021)
CRISPR-Cas9 can cause chromothripsis
Fyodor D. Urnov
NATURE GENETICS (2021)
CRISPR-Cas9 globin editing can induce megabase-scale copy-neutral losses of heterozygosity in hematopoietic cells
J. Boutin et al.
NATURE COMMUNICATIONS (2021)
Frequent loss of heterozygosity in CRISPR-Cas9-edited early human embryos
Gregorio Alanis-Lobato et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2021)
Context is everything: aneuploidy in cancer
Uri Ben-David et al.
NATURE REVIEWS GENETICS (2020)
The long road to the first FDA-approved gene therapy: chimeric antigen receptor T cells targeting CD19
Peter Braendstrup et al.
CYTOTHERAPY (2020)
Unintended on-target chromosomal instability following CRISPR/Cas9 single gene targeting
J. Przewrocka et al.
ANNALS OF ONCOLOGY (2020)
The Emerging Landscape of Immune Cell Therapies
Evan W. Weber et al.
CELL (2020)
Determining the impact of uncharacterized inversions in the human genome by droplet digital PCR
Marta Puig et al.
GENOME RESEARCH (2020)
Detection of Deleterious On-Target Effects after HDR-Mediated CRISPR Editing
Isabel Weisheit et al.
CELL REPORTS (2020)
Cas9 activates the p53 pathway and selects for p53-inactivating mutations
Oana M. Enache et al.
NATURE GENETICS (2020)
Genome editing with CRISPR-Cas nucleases, base editors, transposases and prime editors
Andrew V. Anzalone et al.
NATURE BIOTECHNOLOGY (2020)
CHANGE-seq reveals genetic and epigenetic effects on CRISPR-Cas9 genome-wide activity
Cicera R. Lazzarotto et al.
NATURE BIOTECHNOLOGY (2020)
Allele-Specific Chromosome Removal after Cas9 Cleavage in Human Embryos
Michael Zuccaro et al.
CELL (2020)
Engineered B cells expressing an anti-HIV antibody enable memory retention, isotype switching and clonal expansion
Alessio D. Nahmad et al.
NATURE COMMUNICATIONS (2020)
Identification of preexisting adaptive immunity to Cas9 proteins in humans
Carsten T. Charlesworth et al.
NATURE MEDICINE (2019)
Comprehensive Integration of Single-Cell Data
Tim Stuart et al.
CELL (2019)
Orthotopic replacement of T-cell receptor α- and β-chains with preservation of near-physiological T-cell function
Kilian Schober et al.
NATURE BIOMEDICAL ENGINEERING (2019)
Highly efficient multiplex human T cell engineering without double-strand breaks using Cas9 base editors
Beau R. Webber et al.
NATURE COMMUNICATIONS (2019)
Repair of double-strand breaks induced by CRISPR-Cas9 leads to large deletions and complex rearrangements
Michael Kosicki et al.
NATURE BIOTECHNOLOGY (2018)
Large deletions induced by Cas9 cleavage
Fatwa Adikusuma et al.
NATURE (2018)
Reprogramming human T cell function and specificity with non-viral genome targeting
Theodore L. Roth et al.
NATURE (2018)
Genome-wide CRISPR Screens in Primary Human T Cells Reveal Key Regulators of Immune Function
Eric Shifrut et al.
CELL (2018)
Integration of a CD19 CAR into the. TCR Alpha Chain Locus Streamlines Production of Allogeneic Gene-Edited CAR T Cells
Daniel T. MacLeod et al.
MOLECULAR THERAPY (2017)
Targeting a CAR to the TRAC locus with CRISPR/Cas9 enhances tumour rejection
Justin Eyquem et al.
NATURE (2017)
Molecular remission of infant B-ALL after infusion of universal TALEN gene-edited CAR T cells
Waseem Qasim et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
CRISPR/Cas9-mediated PD-1 disruption enhances anti-tumor efficacy of human chimeric antigen receptor T cells
Levi J. Rupp et al.
SCIENTIFIC REPORTS (2017)
Promoterless gene targeting without nucleases rescues lethality of a Crigler-Najjar syndrome mouse model
Fabiola Porro et al.
EMBO MOLECULAR MEDICINE (2017)
Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases
Mark J. Osborn et al.
MOLECULAR THERAPY (2016)
Dissecting the multicellular ecosystem of metastatic melanoma by single-cell RNA-seq
Itay Tirosh et al.
SCIENCE (2016)
Selective advantage of trisomic human cells cultured in non-standard conditions
Samuel D. Rutledge et al.
SCIENTIFIC REPORTS (2016)
Multiplex Genome-Edited T-cell Manufacturing Platform for Off-the-Shelf Adoptive T-cell Immunotherapies
Laurent Poirot et al.
CANCER RESEARCH (2015)
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
Bernd Zetsche et al.
CELL (2015)
A Multidrug-resistant Engineered CAR T Cell for Allogeneic Combination Immunotherapy
Julien Valton et al.
MOLECULAR THERAPY (2015)
The Molecular Signatures Database Hallmark Gene Set Collection
Arthur Liberzon et al.
CELL SYSTEMS (2015)
Promoter less gene targeting without nucleases ameliorates haemophilia B in mice
A. Barzel et al.
NATURE (2015)
Easy quantitative assessment of genome editing by sequence trace decomposition
Eva K. Brinkman et al.
NUCLEIC ACIDS RESEARCH (2014)
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
Anoop P. Patel et al.
SCIENCE (2014)
Molecular signatures database (MSigDB) 3.0
Arthur Liberzon et al.
BIOINFORMATICS (2011)
High frequency of chromosome 14 deletion in early-onset colon cancer
Najat Mourra et al.
DISEASES OF THE COLON & RECTUM (2007)
Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles
A Subramanian et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Characterization of chromosome 14 abnormalities by interphase in situ hybridization and comparative genomic hybridization in 124 meningiomas
MD Tabernero et al.
AMERICAN JOURNAL OF CLINICAL PATHOLOGY (2005)