Cytotoxic constituents from the leaves and stems of Panax quinquefolius

Review Plant Sciences

A review of the immunomodulatory activities of polysaccharides isolated from Panax species

Yeye Hu et al.

Summary: This article reviews the composition and structural characteristics of purified Panax polysaccharides and discusses their immunomodulatory activities both in vivo and in vitro. Panax polysaccharides can enhance the immune response by activating immune cells and increasing immune indices. Additionally, they have potential therapeutic effects in treating cancer, sepsis, and osteoporosis.

JOURNAL OF GINSENG RESEARCH (2022)

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Article Plant Sciences

Anti-tumor activities of Panax quinquefolius saponins and potential biomarkers in prostate cancer

Shan He et al.

Summary: Panax quinquefolius saponins (PQS) exhibit anti-cancer activity in human prostate cancer cells by inhibiting proliferation and promoting apoptosis. TMEM79 and ACOXL may serve as novel biomarkers for prostate cancer diagnosis.

JOURNAL OF GINSENG RESEARCH (2021)

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Article Biotechnology & Applied Microbiology

Endophytes from Panax species

Rufin Marie Kouipou Toghueo et al.

Summary: This review comprehensively summarized the diversity and biological activity of microbial species living inside Panax species without causing harm, revealing a surprising variety of bacterial and fungal endophytes inhabiting Panax ginseng Meyer and Panax notoginseng (Burkill) F.H.Chen. Studies have shown that some of these endophytes can produce major plant metabolites and convert them into minor or new compounds, demonstrating potential biocontrol abilities against pathogens and the production of secondary metabolites with antimicrobial, antioxidant, anti-inflammatory, and anticancer activities.

BIOCATALYSIS AND AGRICULTURAL BIOTECHNOLOGY (2021)

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Article Chemistry, Multidisciplinary