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Optimization of ultrasound-assisted parthenolide extraction from Tarchonanthus camphoratus leaves using response surface methodology: HPTLC and cytotoxicity analysis

Nasir A. Siddiqui et al.

Summary: This study aimed to optimize ultrasonication extraction of parthenolide from Tarchonanthus camphoratus leaves using Box-Behnken design and validate the method by high performance thin layer chromatography. The extraction parameters were optimized through response surface methodology to maximize parthenolide yield, with validation conducted through cytotoxicity results. The optimized ultrasonic extraction method produced an extraction yield of 1.010% +/- 0.04 %w/w, which was also confirmed by the cytotoxicity results on human hepatoma cells.

ARABIAN JOURNAL OF CHEMISTRY (2021)

Article Oncology

Quercetin Induces Anticancer Activity by Upregulating Pro-NAG-1/GDF15 in Differentiated Thyroid Cancer Cells

Yukyung Hong et al.

Summary: The study suggests that pro-NAG-1 could be a useful biomarker for thyroid cancer and quercetin might be a potential therapeutic target for treating thyroid cancer. The findings indicate that quercetin induced apoptosis by selectively inducing pro-NAG-1 expression, and not mature NAG-1, in thyroid cancer cells. Additionally, the study highlights the importance of identifying novel biomarkers for the diagnosis and treatment of thyroid cancer.

CANCERS (2021)

Review Biochemistry & Molecular Biology

Role of Phytochemicals in Cancer Chemoprevention: Insights

Blassan P. George et al.

Summary: Cancer chemoprevention involves using external agents to slow down or suppress cancer growth, and the occurrence of global cancer types varies depending on factors such as environmental, lifestyle, and genetic factors. Developed countries can prevent cancer with advanced treatment modalities, while developing countries often see it as a painful death sentence.

ANTIOXIDANTS (2021)

Article Toxicology

Investigation of cellular effects of thymoquinone on glioma cell

Eray Metin Guler et al.

Summary: The study found that thymoquinone enhances cytotoxicity, induces DNA damage and apoptosis, and increases intracellular reactive oxygen species in C6 glioma cells. Additionally, thymoquinone decreases mitochondrial membrane potential and glutathione levels, inducing apoptosis by inhibiting pSTAT3. Further research should validate these findings.

TOXICOLOGY REPORTS (2021)

Article Biochemistry & Molecular Biology

Thymoquinone Suppresses the Proliferation, Migration and Invasiveness through Regulating ROS, Autophagic Flux and miR-877-5p in Human Bladder Carcinoma Cells

Xuejian Zhou et al.

Summary: This study confirms the multifaceted effects of thymoquinone (TQ) on bladder carcinoma cells, including inhibition of autophagy and activation of microRNA pathways in suppressing survival, proliferation, migration, and invasion.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2021)

Article Food Science & Technology

Structure-Antioxidant Activity Relationships of Luteolin and Catechin

Seyed Mohammad Ahmadi et al.

JOURNAL OF FOOD SCIENCE (2020)

Review Pharmacology & Pharmacy

Taxane-induced neurotoxicity: Pathophysiology and therapeutic perspectives

Robson da Costa et al.

BRITISH JOURNAL OF PHARMACOLOGY (2020)

Review Medicine, Research & Experimental

The Interplay among miRNAs, Major Cytokines, and Cancer-Related Inflammation

Chiranjib Chakraborty et al.

MOLECULAR THERAPY-NUCLEIC ACIDS (2020)

Article Cell Biology

Alpha-1 antitrypsin deficient individuals have circulating extracellular vesicles with profibrogenic cargo

Nazli Khodayari et al.

CELL COMMUNICATION AND SIGNALING (2020)

Review Biochemistry & Molecular Biology

The role of ubiquitination and deubiquitination in cancer metabolism

Tianshui Sun et al.

MOLECULAR CANCER (2020)

Review Biochemistry & Molecular Biology

Resveratrol and Tumor Microenvironment: Mechanistic Basis and Therapeutic Targets

Wamidh H. Talib et al.

MOLECULES (2020)

Review Pharmacology & Pharmacy

Molecular Mechanisms of Action of Emodin: As an Anti-Cardiovascular Disease Drug

Qianqian Li et al.

FRONTIERS IN PHARMACOLOGY (2020)

Review Chemistry, Medicinal

Parthenolide as Cooperating Agent for Anti-Cancer Treatment of Various Malignancies

Malgorzata Sztiller-Sikorska et al.

PHARMACEUTICALS (2020)

Review Oncology

Chemopreventive and Anticancer Effects of Thymoquinone: Cellular and Molecular Targets

Rohini Gomathinayagam et al.

JOURNAL OF CANCER PREVENTION (2020)

Article Medicine, Research & Experimental

Herb-sourced emodin inhibits angiogenesis of breast cancer by targeting VEGFA transcription

Gengyi Zou et al.

THERANOSTICS (2020)

Review Biochemistry & Molecular Biology

Advances in chemistry and bioactivity of parthenolide

Robert R. A. Freund et al.

NATURAL PRODUCT REPORTS (2020)

Review Biochemistry & Molecular Biology

Glycosides from Medicinal Plants as Potential Anticancer Agents: Emerging Trends Towards Future Drugs

Haroon Khan et al.

CURRENT MEDICINAL CHEMISTRY (2019)

Review Food Science & Technology

Antidiabetic effect of quercetin: A systematic review and meta-analysis of animal studies

Mohammed Bule et al.

FOOD AND CHEMICAL TOXICOLOGY (2019)

Review Chemistry, Medicinal

Health benefits of resveratrol: Evidence from clinical studies

Akhand Pratap Singh et al.

MEDICINAL RESEARCH REVIEWS (2019)

Article Biotechnology & Applied Microbiology

Luteolin suppresses tumor proliferation through inducing apoptosis and autophagy via MAPK activation in glioma

Yijie You et al.

ONCOTARGETS AND THERAPY (2019)

Review Medicine, Research & Experimental

Luteolin, a flavonoid, as an anticancer agent: A review

Muhammad Imran et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

Article Oncology

Emodin inhibits colon cancer by altering BCL-2 family proteins and cell survival pathways

Ian T. Saunders et al.

CANCER CELL INTERNATIONAL (2019)

Review Biochemistry & Molecular Biology

Mechanism of Apoptosis Induced by Curcumin in Colorectal Cancer

Nor Isnida Ismail et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)

Article Medicine, Research & Experimental

Quercetin suppresses the proliferation and metastasis of metastatic osteosarcoma cells by inhibiting parathyroid hormone receptor 1

Shenglong Li et al.

BIOMEDICINE & PHARMACOTHERAPY (2019)

Review Biochemistry & Molecular Biology

Curcumin Combination Chemotherapy: The Implication and Efficacy in Cancer

Bee Ling Tan et al.

MOLECULES (2019)

Article Ophthalmology

Parthenolide inhibits the proliferation and induces the apoptosis of human uveal melanoma cells

Song-Tian Che et al.

INTERNATIONAL JOURNAL OF OPHTHALMOLOGY (2019)

Article Medicine, Research & Experimental

Resveratrol suppresses colon cancer growth by targeting the AKT/STAT3 signaling pathway

Dan Li et al.

INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE (2019)

Article Medicine, Research & Experimental

Allicin suppresses the migration and invasion in cervical cancer cells mainly by inhibiting NRF2

Qiumei Zhang et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2019)

Article Biochemistry & Molecular Biology

Parthenolide Covalently Targets and Inhibits Focal Adhesion Kinase in Breast Cancer Cells

Charles A. Berdan et al.

CELL CHEMICAL BIOLOGY (2019)

Review Oncology

Curcumin and Gastric Cancer: a Review on Mechanisms of Action

Tohid Hassanalilou et al.

JOURNAL OF GASTROINTESTINAL CANCER (2019)

Article Biochemistry & Molecular Biology

Stem Cell Therapy: A New Therapeutic Option for Cardiovascular Diseases

Nasser Hashemi Goradel et al.

JOURNAL OF CELLULAR BIOCHEMISTRY (2018)

Review Cell Biology

MicroRNA: A novel target of curcumin in cancer therapy

Hamed Mirzaei et al.

JOURNAL OF CELLULAR PHYSIOLOGY (2018)

Article Biochemistry & Molecular Biology

Curcumin formulated in solid lipid nanoparticles has enhanced efficacy in Hodgkin's lymphoma in mice

Jacob Guorgui et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2018)

Review Biochemistry & Molecular Biology

Podophyllotoxin derivatives as an excellent anticancer aspirant for future chemotherapy: A key current imminent needs

Xu Zhang et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2018)

Review Pharmacology & Pharmacy

Safer anti-inflammatory therapy through dual COX-2/5-LOX inhibitors: A structure-based approach

Jaismy P. Jacob et al.

EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES (2018)

Review Biochemistry & Molecular Biology

Anti-Inflammatory Effects of Resveratrol: Mechanistic Insights

Diego de Sa Coutinho et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Review Plant Sciences

Anti-inflammatory effects of luteolin: A review of in vitro, in vivo, and in silico studies

Nur Aziz et al.

JOURNAL OF ETHNOPHARMACOLOGY (2018)

Article Food Science & Technology

Flavonoids Luteolin and Quercetin Inhibit RPS19 and contributes to metastasis of cancer cells through c-Myc reduction

Ku-Chung Chen et al.

JOURNAL OF FOOD AND DRUG ANALYSIS (2018)

Review Medicine, Research & Experimental

Resveratrol: An overview of its anti-cancer mechanisms

Mohamed Elshaer et al.

LIFE SCIENCES (2018)

Review Biochemistry & Molecular Biology

Melatonin and Cancer Hallmarks

Wamidh H. Talib

MOLECULES (2018)

Article Biochemistry & Molecular Biology

Parthenolide Inhibits STAT3 Signaling by Covalently Targeting Janus Kinases

Man Liu et al.

MOLECULES (2018)

Review Biotechnology & Applied Microbiology

Primary effusion lymphoma: current perspectives

Mayur Narkhede et al.

ONCOTARGETS AND THERAPY (2018)

Article Medicine, Research & Experimental

Curcumin inhibits proliferation and promotes apoptosis of breast cancer cells

Shan Hu et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2018)

Article Medicine, Research & Experimental

Allicin activates autophagic cell death to alleviate the malignant development of thyroid cancer

Yangfeng Xiang et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2018)

Meeting Abstract Cardiac & Cardiovascular Systems

Thymoquinone alters ionic currents and decreases β adrenergic response in rat ventricle myocytes

T. Mercan et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2018)

Review Medicine, General & Internal

Aged Garlic and Cancer: A Systematic Review

Maryam Miraghajani et al.

INTERNATIONAL JOURNAL OF PREVENTIVE MEDICINE (2018)

Review Oncology

Role of curcumin in regulating p53 in breast cancer: an overview of the mechanism of action

Wamidh H. Talib et al.

BREAST CANCER-TARGETS AND THERAPY (2018)

Review Biochemistry & Molecular Biology

Role of resveratrol in regulation of cellular defense systems against oxidative stress

Van-Long Truong et al.

BIOFACTORS (2018)

Review Biochemistry & Molecular Biology

Subunit-Specific Role of NF-kappa B in Cancer

Barbara Kaltschmidt et al.

BIOMEDICINES (2018)

Review Biochemistry & Molecular Biology

Plant-Derived Anticancer Agents: Lessons from the Pharmacology of Geniposide and Its Aglycone, Genipin

Solomon Habtemariam et al.

BIOMEDICINES (2018)

Review Pharmacology & Pharmacy

Antioxidant effects of resveratrol in the cardiovascular system

Ning Xia et al.

BRITISH JOURNAL OF PHARMACOLOGY (2017)

Article Biotechnology & Applied Microbiology

Anticancer activities of epigallocatechin-3-gallate against cholangiocarcinoma cells

Tae Won Kwak et al.

ONCOTARGETS AND THERAPY (2017)

Review Chemistry, Medicinal

Natural alkaloids as P-gp inhibitors for multidrug resistance reversal in cancer

Prashant Joshi et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)

Review Biochemistry & Molecular Biology

The Role of Resveratrol in Cancer Therapy

Jeong-Hyeon Ko et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Chemistry, Medicinal

Polyphenolic Phytochemicals in Cancer Prevention and Therapy: Bioavailability versus Bioefficacy

Jose M. Estrela et al.

JOURNAL OF MEDICINAL CHEMISTRY (2017)

Review Chemistry, Medicinal

Cardiovascular Protective Effects and Clinical Applications of Resveratrol

Sanghyun Cho et al.

JOURNAL OF MEDICINAL FOOD (2017)

Article Biochemistry & Molecular Biology

Quercetin induces apoptosis and autophagy in primary effusion lymphoma cells by inhibiting PI3K/AKT/mTOR and STAT3 signaling pathways

Marisa Granato et al.

JOURNAL OF NUTRITIONAL BIOCHEMISTRY (2017)

Review Biochemistry & Molecular Biology

Emerging Cytotoxic Alkaloids in the Battle against Cancer: Overview of Molecular Mechanisms

Zeina Habli et al.

MOLECULES (2017)

Article Chemistry, Medicinal

Rutin, a Quercetin Glycoside, Restores Chemosensitivity in Human Breast Cancer Cells

Marcello Iriti et al.

PHYTOTHERAPY RESEARCH (2017)

Review Chemistry, Medicinal

A systematic review on ethnomedicines of anticancer plants

Akash Tariq et al.

PHYTOTHERAPY RESEARCH (2017)

Article Public, Environmental & Occupational Health

Antitumor effect of thymoquinone combined with resveratrol on mice transplanted with breast cancer

Omar H. Alobaedi et al.

ASIAN PACIFIC JOURNAL OF TROPICAL MEDICINE (2017)

Article Biotechnology & Applied Microbiology

Parthenolide suppresses pancreatic cell growth by autophagy-mediated apoptosis

Weifeng Liu et al.

ONCOTARGETS AND THERAPY (2017)

Review Pharmacology & Pharmacy

Luteolin: A Flavonoid that Has Multiple Cardio-Protective Effects and Its Molecular Mechanisms

Yuanyuan Luo et al.

FRONTIERS IN PHARMACOLOGY (2017)

Article Cell Biology

Luteolin Promotes Cell Apoptosis by Inducing Autophagy in Hepatocellular Carcinoma

Zhijia Cao et al.

CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)

Review Tropical Medicine

Plant-derived anticancer agents: A green anticancer approach

Javed Iqbal et al.

ASIAN PACIFIC JOURNAL OF TROPICAL BIOMEDICINE (2017)

Review Oncology

Genistein: Its role in metabolic diseases and cancer

Vidya Mukund et al.

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2017)

Review Food Science & Technology

Curcumin: A Review of Its Effects on Human Health

Susan J. Hewlings et al.

FOODS (2017)

Article Medicine, Research & Experimental

Anticancer activity of baicalein and luteolin studied in colorectal adenocarcinoma LoVo cells and in drug-resistant LoVo/Dx cells

Anna Palko-Labuz et al.

BIOMEDICINE & PHARMACOTHERAPY (2017)

Article Biotechnology & Applied Microbiology

Parthenolide induces apoptosis and autophagy through the suppression of PI3K/Akt signaling pathway in cervical cancer

Sridharan Jeyamohan et al.

BIOTECHNOLOGY LETTERS (2016)

Review Chemistry, Medicinal

Emodin: A Review of its Pharmacology, Toxicity and Pharmacokinetics

Xiaoxv Dong et al.

PHYTOTHERAPY RESEARCH (2016)

Article Gastroenterology & Hepatology

Thymoquinone inhibits proliferation in gastric cancer via the STAT3 pathway in vivo and in vitro

Wen-Qian Zhu et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2016)

Review Nutrition & Dietetics

Quercetin, Inflammation and Immunity

Yao Li et al.

NUTRIENTS (2016)

Review Oncology

Role of DUSP1/MKP1 in tumorigenesis, tumor progression and therapy

Jiliang Shen et al.

CANCER MEDICINE (2016)

Review Integrative & Complementary Medicine

Characteristics and Health Benefits of Phytochemicals

Claus Leitzmann

FORSCHENDE KOMPLEMENTARMEDIZIN (2016)

Article Public, Environmental & Occupational Health

Thymoquinone supplementation ameliorates lead-induced testis function impairment in adult rats

Aymen Mabrouk et al.

TOXICOLOGY AND INDUSTRIAL HEALTH (2016)

Review Nutrition & Dietetics

Anticancer Molecular Mechanisms of Resveratrol

Elena M. Varoni et al.

FRONTIERS IN NUTRITION (2016)

Article Endocrinology & Metabolism

Quercetin-Induced Cell Death in Human Papillary Thyroid Cancer (B-CPAP) Cells

Ergul Mutlu Altundag et al.

JOURNAL OF THYROID RESEARCH (2016)

Review Oncology

Garlic and Onions: Their Cancer Prevention Properties

Holly L. Nicastro et al.

CANCER PREVENTION RESEARCH (2015)

Article Biochemistry & Molecular Biology

The Role of Dietary Polyphenols in the Management of Inflammatory Bowel Disease

Mohammad H. Farzaei et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2015)

Article Chemistry, Physical

Structural Properties of Green Tea Catechins

Dominic Botten et al.

JOURNAL OF PHYSICAL CHEMISTRY B (2015)

Article Cell Biology

Mechanisms of Thymoquinone Hepatorenal Protection in Methotrexate-Induced Toxicity in Rats

Azza A. K. El-Sheikh et al.

MEDIATORS OF INFLAMMATION (2015)

Review Pharmacology & Pharmacy

Thymoquinone and its therapeutic potentials

Sara Darakhshan et al.

PHARMACOLOGICAL RESEARCH (2015)

Review Oncology

Therapeutic targeting of replicative immortality

Paul Yaswen et al.

SEMINARS IN CANCER BIOLOGY (2015)

Review Food Science & Technology

Effect of curcuminoids on oxidative stress: A systematic review and meta-analysis of randomized controlled trials

Amirhossein Sahebkar et al.

JOURNAL OF FUNCTIONAL FOODS (2015)

Review Nutrition & Dietetics

Genistein and Cancer: Current Status, Challenges, and Future Directions

Carmela Spagnuolo et al.

ADVANCES IN NUTRITION (2015)

Article Pharmacology & Pharmacy

NLRP3 inflammasome and its inhibitors: a review

Bo-Zong Shao et al.

FRONTIERS IN PHARMACOLOGY (2015)

Article Biochemistry & Molecular Biology

Quercetin Suppresses HeLa Cells by Blocking PI3K/Akt Pathway

Tao Xiang et al.

JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES (2014)

Review Biochemistry & Molecular Biology

Allicin: Chemistry and Biological Properties

Jan Borlinghaus et al.

MOLECULES (2014)

Article Biochemistry & Molecular Biology

Mechanisms enforcing the estrogen receptor β selectivity of botanical estrogens

Yan Jiang et al.

FASEB JOURNAL (2013)

Article Food Science & Technology

Resveratrol and related stilbenes: Their anti-aging and anti-angiogenic properties

Konstantinos M. Kasiotis et al.

FOOD AND CHEMICAL TOXICOLOGY (2013)

Article Genetics & Heredity

MiR-142-3p functions as a tumor suppressor by targeting CD133, ABCG2, and Lgr5 in colon cancer cells

Wei-Wei Shen et al.

JOURNAL OF MOLECULAR MEDICINE-JMM (2013)

Article Chemistry, Medicinal

A Review of the Cardiovascular Benefits and Antioxidant Properties of Allicin

Jackie Yan-Yan Chan et al.

PHYTOTHERAPY RESEARCH (2013)

Article Pharmacology & Pharmacy

Thymoquinone suppresses metastasis of melanoma cells by inhibition of NLRP3 inflammasome

Israr Ahmad et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2013)

Review Cell Biology

Evading apoptosis in cancer

Kaleigh Fernald et al.

TRENDS IN CELL BIOLOGY (2013)

Article Pharmacology & Pharmacy

Cellular responses with thymoquinone treatment in human breast cancer cell line MCF-7

Marjaneh Motaghed et al.

PHARMACOGNOSY RESEARCH (2013)

Article Integrative & Complementary Medicine

Curcumin induces the apoptosis of human monocytic leukemia THP-1 cells via the activation of JNK/ERK Pathways

Chu-Wen Yang et al.

BMC COMPLEMENTARY AND ALTERNATIVE MEDICINE (2012)

Review Medicine, Research & Experimental

Anti-Cancer Activities of Tea Epigallocatechin-3-Gallate in Breast Cancer Patients under Radiotherapy

G. Zhang et al.

CURRENT MOLECULAR MEDICINE (2012)

Article Oncology

Trans-Resveratrol Alters Mammary Promoter Hypermethylation in Women at Increased Risk for Breast Cancer

Weizhu Zhu et al.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2012)

Review Cell Biology

New aspects of the Warburg effect in cancer cell biology

Steven J. Bensinger et al.

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY (2012)

Review Medicine, General & Internal

Anticancer potential of emodin

Shu-Chun Hsu et al.

BIOMEDICINE-TAIWAN (2012)

Article Pharmacology & Pharmacy

Anticancer activity of thymoquinone in breast cancer cells: Possible involvement of PPAR-γ pathway

Chern Chiuh Woo et al.

BIOCHEMICAL PHARMACOLOGY (2011)

Review Biochemistry & Molecular Biology

Hallmarks of Cancer: The Next Generation

Douglas Hanahan et al.

Review Biochemistry & Molecular Biology

Hypoxia Inducible Factor-1 as a Target for Neurodegenerative Diseases

Z. Zhang et al.

CURRENT MEDICINAL CHEMISTRY (2011)

Article Biochemistry & Molecular Biology

S-allylmercapto-N-acetylcysteine up-regulates cellular glutathione and protects vascular endothelial cells from oxidative stress

Nira Izigov et al.

FREE RADICAL BIOLOGY AND MEDICINE (2011)

Article Gastroenterology & Hepatology

Consumption of Large Amounts of Allium Vegetables Reduces Risk for Gastric Cancer in a Meta-analysis

Yong Zhou et al.

GASTROENTEROLOGY (2011)

Article Biotechnology & Applied Microbiology

Thymoquinone up-regulates PTEN expression and induces apoptosis in doxorubicin-resistant human breast cancer cells

El-Shaimaa A. Arafa et al.

MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS (2011)

Review Biochemistry & Molecular Biology

The antioxidant and pro-oxidant activities of green tea polyphenols: A role in cancer prevention

Joshua D. Lambert et al.

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (2010)

Article Oncology

Green tea consumption and breast cancer risk or recurrence: a meta-analysis

Adeyemi A. Ogunleye et al.

BREAST CANCER RESEARCH AND TREATMENT (2010)

Article Biochemistry & Molecular Biology

(-)-Epigallocatechin gallate inhibits growth and activation of the VEGF/VEGFR axis in human colorectal cancer cells

Masahito Shimizu et al.

CHEMICO-BIOLOGICAL INTERACTIONS (2010)

Article Food Science & Technology

Antioxidant properties of resveratrol: A structure-activity insight

Ilhami Gulcin

INNOVATIVE FOOD SCIENCE & EMERGING TECHNOLOGIES (2010)

Article Oncology

Allicin Purified From Fresh Garlic Cloves Induces Apoptosis in Colon Cancer Cells Via Nrf2

Wolf Bat-Chen et al.

NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL (2010)

Article Medicine, Research & Experimental

Thymoquinone hydrazone derivatives cause cell cycle arrest in p53-competent colorectal cancer cells

Andre Wirries et al.

EXPERIMENTAL AND THERAPEUTIC MEDICINE (2010)

Article Multidisciplinary Sciences

Protective Mechanism of Quercetin and Rutin Using Glutathione Metabolism on H2O2-induced Oxidative Stress in HepG2 Cells

Gyo-Nam Kim et al.

NATURAL COMPOUNDS AND THEIR ROLE IN APOPTOTIC CELL SIGNALING PATHWAYS (2009)

Article Multidisciplinary Sciences

Genistein Inhibits Cell Growth by Modulating Various Mitogen-Activated Protein Kinases and AKT in Cervical Cancer Cells

Su-Hyeon Kim et al.

NATURAL COMPOUNDS AND THEIR ROLE IN APOPTOTIC CELL SIGNALING PATHWAYS (2009)

Review Clinical Neurology

Tumour angiogenesis: Its mechanism and therapeutic implications in malignant gliomas

Michael L. H. Wong et al.

JOURNAL OF CLINICAL NEUROSCIENCE (2009)

Article Oncology

Emodin enhances cytotoxicity of chemotherapeutic drugs in prostate cancer cells

Xin-zhi Huang et al.

CANCER BIOLOGY & THERAPY (2008)

Review Oncology

Multi-targeted therapy of cancer by genistein

Sanjeev Banerjee et al.

CANCER LETTERS (2008)

Article Oncology

Phase II trial of curcumin in patients with advanced pancreatic cancer

Navneet Dhillon et al.

CLINICAL CANCER RESEARCH (2008)

Article Environmental Sciences

Modulation of gene methylation by genistein or lycopene in breast cancer cells

Audrey King-Batoon et al.

ENVIRONMENTAL AND MOLECULAR MUTAGENESIS (2008)

Review Biochemistry & Molecular Biology

Cell cycle control as a basis for cancer chemoprevention through dietary agents

Syed Musthapa Meeran et al.

FRONTIERS IN BIOSCIENCE-LANDMARK (2008)

Article Nutrition & Dietetics

Quercetin from shallots (Allium cepa L. var. aggregatum) is more bioavailable than its glucosides

Wieslaw Wiczkowski et al.

JOURNAL OF NUTRITION (2008)

Article Oncology

Genistein down-regulates androgen receptor by modulating HDAC6-Hsp90 chaperone function

Shashwati Basak et al.

MOLECULAR CANCER THERAPEUTICS (2008)

Review Oncology

Soy isoflavone genistein in prevention and treatment of prostate cancer

F. G. E. Perabo et al.

PROSTATE CANCER AND PROSTATIC DISEASES (2008)

Review Oncology

Hypoxia and metabolism - Opinion - The interplay between MYC and HIF in cancer

Chi V. Dang et al.

NATURE REVIEWS CANCER (2008)

Review Oncology

Curcumin for chemoprevention of colon cancer

Jeremy James Johnson et al.

CANCER LETTERS (2007)

Article Pharmacology & Pharmacy

Emodin, an anthraquinone derivative from Rheum officinale Baill, enhances cutaneous wound healing in rats

Tian Tang et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2007)

Review Cell Biology

Molecular regulation of angiogenesis and lymphangiogenesis

Ralf H. Adams et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2007)

Review Chemistry, Medicinal

Molecular mechanism of emodin action: transition from laxative ingredient to an antitumor agent

Gopal Srinivas et al.

MEDICINAL RESEARCH REVIEWS (2007)

Article Agriculture, Multidisciplinary

Impact of quercetin and EGCG on key elements of the Wnt pathway in human colon carcinoma cells

Gudrun Pahlke et al.

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY (2006)

Article Gastroenterology & Hepatology

Combination treatment with curcumin and quercetin of adenomas in familial adenomatous polyposis

Marcia Cruz-Correa et al.

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2006)

Article Oncology

Meta-analysis of soy intake and breast cancer risk

BJ Trock et al.

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE (2006)

Review Chemistry, Medicinal

The role of Genistein and synthetic derivatives of isoflavone in cancer prevention and therapy

FH Sarkar et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2006)

Article Nutrition & Dietetics

Aged garlic extract has potential suppressive effect on colorectal adenomas in humans

S Tanaka et al.

JOURNAL OF NUTRITION (2006)

Article Chemistry, Multidisciplinary

Effect of curcumin on multidrug resistance in resistant human gastric carcinoma cell line SGC7901/VCR

XQ Tang et al.

ACTA PHARMACOLOGICA SINICA (2005)

Article Biochemistry & Molecular Biology

Structure-activity relationship of the tocopherol-regeneration reaction by catechins

K Mukai et al.

FREE RADICAL BIOLOGY AND MEDICINE (2005)

Review Biochemistry & Molecular Biology

Anthocyanins and other flavonoids

CA Williams et al.

NATURAL PRODUCT REPORTS (2004)

Article Gastroenterology & Hepatology

Effects of allicin on both telomerase activity and apoptosis in gastric cancer SGC-7901 cells

L Sun et al.

WORLD JOURNAL OF GASTROENTEROLOGY (2003)

Review Oncology

Tumorigenesis and the angiogenic switch

G Bergers et al.

NATURE REVIEWS CANCER (2003)

Article Chemistry, Multidisciplinary

Thymoquinone is a potent superoxide anion scavenger

OA Badary et al.

DRUG AND CHEMICAL TOXICOLOGY (2003)

Article Medicine, Research & Experimental

Therapeutic potential of inhibition of the NF-kappa B pathway in the treatment of inflammation and cancer

Y Yamamoto et al.

JOURNAL OF CLINICAL INVESTIGATION (2001)

Review Biochemistry & Molecular Biology

Advances in flavonoid research since 1992

JB Harborne et al.

PHYTOCHEMISTRY (2000)