4.6 Article

Quantitative Proteomics Explore the Potential Targets and Action Mechanisms of Hydroxychloroquine

Related references

Note: Only part of the references are listed.
Article Cell Biology

BPIFB3 interacts with ARFGAP1 and TMED9 to regulate non-canonical autophagy and RNA virus infection

Azia S. Evans et al.

Summary: The paragraph discusses the role of autophagy pathways in viral infections, as well as the negative regulatory role of the BPIFB3 protein in non-canonical autophagy, affecting the replication of enteroviruses and flaviviruses. It was found that BPIFB3 depletion-induced autophagy does not require components of the traditional autophagy machinery, and two cellular factors were identified to facilitate its role in viral replication.

JOURNAL OF CELL SCIENCE (2021)

Article Cell Biology

VDAC1 promotes cardiomyocyte autophagy in anoxia/reoxygenation injury via the PINK1/Parkin pathway

Xiaomei Yang et al.

Summary: Research has shown that VDAC1 plays a role in mediating cellular damage during myocardial ischemia/reperfusion injury by activating autophagy and affecting mitochondrial function and apoptosis. Knockdown of VDAC1 can alleviate cell damage, and A/R injury also activates the PINK1/Parkin autophagic pathway.

CELL BIOLOGY INTERNATIONAL (2021)

Review Endocrinology & Metabolism

Autophagy in metabolic disease and ageing

Munehiro Kitada et al.

Summary: Dysfunctional autophagy can lead to various diseases, particularly age-related metabolic derangements such as insulin resistance, type 2 diabetes mellitus, and sarcopenic obesity. The decline in autophagic efficiency with age and the interference of overnutrition can exacerbate these conditions by accumulating damaged cellular components. Developing autophagy-based therapies may hold potential in treating metabolic diseases associated with aging.

NATURE REVIEWS ENDOCRINOLOGY (2021)

Article Biochemistry & Molecular Biology

The reactome pathway knowledgebase

Bijay Jassal et al.

NUCLEIC ACIDS RESEARCH (2020)

Review Rheumatology

Mechanisms of action of hydroxychloroquine and chloroquine: implications for rheumatology

Eva Schrezenmeier et al.

NATURE REVIEWS RHEUMATOLOGY (2020)

Article Multidisciplinary Sciences

Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I

Keisuke Yamamoto et al.

NATURE (2020)

Editorial Material Cell Biology

Galectins control MTOR and AMPK in response to lysosomal damage to induce autophagy

Jingyue Jia et al.

AUTOPHAGY (2019)

Article Multidisciplinary Sciences

Selective autophagy maintains centrosome integrity and accurate mitosis by turnover of centriolar satellites

Sos Gronbaek Holdgaard et al.

NATURE COMMUNICATIONS (2019)

Article Biochemical Research Methods

Cytoscape StringApp: Network Analysis and Visualization of Proteomics Data

Nadezhda T. Doncheva et al.

JOURNAL OF PROTEOME RESEARCH (2019)

Review Biochemistry & Molecular Biology

The Functional Role of SEC23 in Vesicle Transportation, Autophagy and Cancer

Jingchen Jing et al.

INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)

Review Oncology

Targeting Autophagy in Cancer

Angelique V. Onorati et al.

CANCER (2018)

Review Chemistry, Medicinal

The Role of Quinidine in the Pharmacological Therapy of Ventricular Arrhythmias 'Quinidine'

Bojana Bozic et al.

MINI-REVIEWS IN MEDICINAL CHEMISTRY (2018)

Article Medicine, Research & Experimental

Chloroquine and hydroxychloroquine inhibit bladder cancer cell growth by targeting basal autophagy and enhancing apoptosis

Yi-Chia Lin et al.

KAOHSIUNG JOURNAL OF MEDICAL SCIENCES (2017)

Review Biochemistry & Molecular Biology

mTOR Signaling in Growth, Metabolism, and Disease

Robert A. Saxton et al.

Review Public, Environmental & Occupational Health

Historical Review: Problematic Malaria Prophylaxis with Quinine

G. Dennis Shanks

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2016)

Article Medicine, Research & Experimental

Fungistatic effect of hydroxychloroquine, lessons from a case

Fazlollah Keshavarzi

MEDICAL MYCOLOGY CASE REPORTS (2016)

Article Biochemistry & Molecular Biology

Hydroxychloroquine-Inhibited Dengue Virus Is Associated with Host Defense Machinery

Li-Fong Wang et al.

JOURNAL OF INTERFERON AND CYTOKINE RESEARCH (2015)

Article Infectious Diseases

Treatment of classic Whipple's disease: from in vitro results to clinical outcome

Jean-Christophe Lagier et al.

JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2014)

Article Multidisciplinary Sciences

Tracking cancer drugs in living cells by thermal profiling of the proteome

Mikhail M. Savitski et al.

SCIENCE (2014)

Review Endocrinology & Metabolism

G protein-coupled receptors and the regulation of autophagy

Eric M. Wauson et al.

TRENDS IN ENDOCRINOLOGY AND METABOLISM (2014)

Review Infectious Diseases

Antimicrobial therapies for Q fever

Gilbert J. Kersh

EXPERT REVIEW OF ANTI-INFECTIVE THERAPY (2013)

Article Biochemistry & Molecular Biology

Tnfaip8l1/Oxi-β binds to FBXW5, increasing autophagy through activation of TSC2 in a Parkinson's disease model

Ji-Young Ha et al.

JOURNAL OF NEUROCHEMISTRY (2013)

Article Oncology

A Phase I Study of Erlotinib and Hydroxychloroquine in Advanced Non-Small-Cell Lung Cancer

Sarah B. Goldberg et al.

JOURNAL OF THORACIC ONCOLOGY (2012)

Article Multidisciplinary Sciences

Galectin 8 targets damaged vesicles for autophagy to defend cells against bacterial invasion

Teresa L. M. Thurston et al.

NATURE (2012)

Article Cell Biology

Pancreatic cancers require autophagy for tumor growth

Shenghong Yang et al.

GENES & DEVELOPMENT (2011)

Article Biochemistry & Molecular Biology

LC3 and GATE-16/GABARAP subfamilies are both essential yet act differently in autophagosome biogenesis

Hilla Weidberg et al.

EMBO JOURNAL (2010)

Article Ophthalmology

Induction of Lysosomal Dilatation, Arrested Autophagy, and Cell Death by Chloroquine in Cultured ARPE-19 Cells

Young Hee Yoon et al.

INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2010)

Article Biochemistry & Molecular Biology

A Role for NBR1 in Autophagosomal Degradation of Ubiquitinated Substrates

Vladimir Kirkin et al.

MOLECULAR CELL (2009)

Article Biochemistry & Molecular Biology

JNK1-mediated phosphorylation of BcI-2 regulates starvation-induced autophagy

Yongjie Wei et al.

MOLECULAR CELL (2008)

Review Pharmacology & Pharmacy

Stereoselectivity in the pharmacodynamics and pharmacokinetics of the chiral antimalarial drugs

DR Brocks et al.

CLINICAL PHARMACOKINETICS (2003)

Article Cell Biology

Assembly of centrosomal proteins and microtubule organization depends on PCM-1

A Dammermann et al.

JOURNAL OF CELL BIOLOGY (2002)