Journal
MOLECULES
Volume 27, Issue 14, Pages -Publisher
MDPI
DOI: 10.3390/molecules27144428
Keywords
anticancer; cyclic peptide; mechanism of anticancer; in vitro; in vivo
Funding
- Academic Leadership Grant of Universitas Padjadjaran [2203/UN6.3.1/PT.00/2022]
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Cyclic peptides have been widely studied as potential anticancer agents, showing efficacy against various types of cancer. This review summarizes the findings from previous studies and discusses the different cyclic peptide compounds, their sources, and modes of action. The prospects and future directions of cyclic peptides for clinical applications are also described.
Cyclic peptides have been widely reported to have therapeutic abilities in the treatment of cancer. This has been proven through in vitro and in vivo studies against breast, lung, liver, colon, and prostate cancers, among others. The multitude of data available in the literature supports the potential of cyclic peptides as anticancer agents. This review summarizes the findings from previously reported studies and discusses the different cyclic peptide compounds, the sources, and their modes of action as anticancer agents. The prospects and future of cyclic peptides will also be described to give an overview on the direction of cyclic peptide development for clinical applications.
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