4.8 Editorial Material

What's NEXT for the exosome?

Journal

MOLECULAR CELL
Volume 82, Issue 13, Pages 2355-2357

Publisher

CELL PRESS
DOI: 10.1016/j.molcel.2022.06.017

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Funding

  1. European Molecular Biology Laboratory
  2. EMBL Interdisciplinary Postdoc (EIPOD4) program under Marie Sklodowska-Curie Actions COFUND [847543]
  3. Marie Curie Actions (MSCA) [847543] Funding Source: Marie Curie Actions (MSCA)

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The two recent studies shed light on the assembly of the nuclear exosome targeting complex (NEXT) and its mechanism for degrading specific classes of RNA, providing valuable insights into cellular RNA degradation processes.
Two recent studies by Gerlach et al. (2022) and Puno and Lima (2022) provide new structural and functional insight into the assembly of the nuclear exosome targeting complex (NEXT) and how it may target specific classes of RNA for degradation.

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