Related references
Note: Only part of the references are listed.TGF-β1 is involved in senescence-related pathways in glomerular endothelial cells via p16 translocation and p21 induction
Sayo Ueda et al.
SCIENTIFIC REPORTS (2021)
Roles of XBP1s in Transcriptional Regulation of Target Genes
Sung-Min Park et al.
BIOMEDICINES (2021)
The ER Unfolded Protein Response Effector, ATF6, Reduces Cardiac Fibrosis and Decreases Activation of Cardiac Fibroblasts
Winston T. Stauffer et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
Mechanisms, regulation and functions of the unfolded protein response
Claudio Hetz et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
High expression of spliced X-Box Binding Protein 1 in lung tumors is associated with cancer aggressiveness and epithelial-to-mesenchymal transition
Quentin Tavernier et al.
SCIENTIFIC REPORTS (2020)
Tumor cells rely on the thiol oxidoreductase PDI for PERK signaling in order to survive ER stress
Philip Kranz et al.
SCIENTIFIC REPORTS (2020)
The UPR Transducer IRE1 Promotes Breast Cancer Malignancy by Degrading Tumor Suppressor microRNAs
Kezhong Zhang et al.
ISCIENCE (2020)
Activation of the IRE1 RNase through remodeling of the kinase front pocket by ATP-competitive ligands
Elena Ferri et al.
NATURE COMMUNICATIONS (2020)
The Role of Endoplasmic Reticulum Stress in Cell Survival and Death
Benjamin G. Spencer et al.
JOURNAL OF COMPARATIVE PATHOLOGY (2020)
IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
Xia Sheng et al.
NATURE COMMUNICATIONS (2019)
The multiple roles of the unfolded protein response regulator IRE1α in cancer
Fiona Chalmers et al.
MOLECULAR CARCINOGENESIS (2019)
4-Phenylbutyric Acid Reduces Endoplasmic Reticulum Stress in Chondrocytes That Is Caused by Loss of the Protein Disulfide Isomerase ERp57
Yvonne Rellmann et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
The endoplasmic reticulum (ER) chaperone BiP is a master regulator of ER functions: Getting by with a little help from ERdj friends
Kristine Faye R. Pobre et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2019)
Structure and Molecular Mechanism of ER Stress Signaling by the Unfolded Protein Response Signal Activator IRE1
Christopher J. Adams et al.
FRONTIERS IN MOLECULAR BIOSCIENCES (2019)
Widespread PERK-dependent repression of ER targets in response to ER stress
Nir Gonen et al.
SCIENTIFIC REPORTS (2019)
Dual IRE1 RNase functions dictate glioblastoma development
Stephanie Lhomond et al.
EMBO MOLECULAR MEDICINE (2018)
Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization
Chih-Hang Anthony Tang et al.
JOURNAL OF CELL BIOLOGY (2018)
Endoplasmic reticulum stress in the pathogenesis of fibrotic disease
Jonathan A. Kropski et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Coordination between Two Branches of the Unfolded Protein Response Determines Apoptotic Cell Fate
Tsun-Kai Chang et al.
MOLECULAR CELL (2018)
Inhibition of IRE1 RNase activity modulates the tumor cell secretome and enhances response to chemotherapy
Susan E. Logue et al.
NATURE COMMUNICATIONS (2018)
Genome-wide analyses reveal the IRE1a-XBP1 pathway promotes T helper cell differentiation by resolving secretory stress and accelerating proliferation
Jhuma Pramanik et al.
GENOME MEDICINE (2018)
A lifetime of stress: ATF6 in development and homeostasis
Robert F. Hillary et al.
JOURNAL OF BIOMEDICAL SCIENCE (2018)
Loss of TGF- signaling drives cSCC from skin stem cells - More evidence
Aidan M. Rose et al.
CELL CYCLE (2017)
ER stress and distinct outputs of the IRE1α RNase control proliferation and senescence in response to oncogenic Ras
Nicholas Blazanin et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Activation of TGF-β signaling induces cell death via the unfolded protein response in Fuchs endothelial corneal dystrophy
Naoki Okumura et al.
SCIENTIFIC REPORTS (2017)
Endoplasmic Reticulum Stress, Unfolded Protein Response, and Cancer Cell Fate
Marco Corazzari et al.
FRONTIERS IN ONCOLOGY (2017)
Roles of TGF-β signaling pathway in endoplasmic reticulum stress in endothelial cells stimulated with cigarette smoke extract
Hong Huang et al.
JOURNAL OF HUAZHONG UNIVERSITY OF SCIENCE AND TECHNOLOGY-MEDICAL SCIENCES (2017)
The Role of the PERK/eIF2 alpha/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress
W. Rozpedek et al.
CURRENT MOLECULAR MEDICINE (2016)
miR-663 overexpression induced by endoplasmic reticulum stress modulates hepatocellular carcinoma cell apoptosis via transforming growth factor beta 1
Yawei Huang et al.
ONCOTARGETS AND THERAPY (2016)
Endoplasmic Reticulum Stress and the Hallmarks of Cancer
Hery Urra et al.
TRENDS IN CANCER (2016)
PERK regulated miR-424(322)-503 cluster fine-tunes activation of IRE1 and ATF6 during Unfolded Protein Response
Ananya Gupta et al.
SCIENTIFIC REPORTS (2015)
Allosteric Inhibition of the IRE1α RNase Preserves Cell Viability and Function during Endoplasmic Reticulum Stress
Rajarshi Ghosh et al.
CELL (2014)
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway
Xi Chen et al.
NATURE (2014)
IRE1 Phosphatase PP2Ce Regulates Adaptive ER Stress Response in the Postpartum Mammary Gland
Shuxun Ren et al.
PLOS ONE (2014)
Getting RIDD of RNA: IRE1 in cell fate regulation
M. Maurel et al.
TRENDS IN BIOCHEMICAL SCIENCES (2014)
Phosphoregulation of Ire1 RNase splicing activity
Filippo Prischi et al.
NATURE COMMUNICATIONS (2014)
The impact of the endoplasmic reticulum protein-folding environment on cancer development
Miao Wang et al.
NATURE REVIEWS CANCER (2014)
Detection and quantification of endoplasmic reticulum stress in living cells using the fluorescent compound, Thioflavin T
Daniel R. Beriault et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2013)
PPM1l encodes an inositol requiring-protein 1 (IRE1) specific phosphatase that regulates the functional outcome of the ER stress response
Gang Lu et al.
MOLECULAR METABOLISM (2013)
Involvement of Endoplasmic Reticulum Stress in Myofibroblastic Differentiation of Lung Fibroblasts
Hyun Ah Baek et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2012)
The role of endoplasmic reticulum stress and the unfolded protein response in fibrosis
Stefania Lenna et al.
CURRENT OPINION IN RHEUMATOLOGY (2012)
Ser7 Phosphorylation of the CTD Recruits the RPAP2 Ser5 Phosphatase to snRNA Genes
Sylvain Egloff et al.
MOLECULAR CELL (2012)
Switching TGFβ from a tumor suppressor to a tumor promoter
Gareth J. Inman
CURRENT OPINION IN GENETICS & DEVELOPMENT (2011)
Structure of the Ire1 autophosphorylation complex and implications for the unfolded protein response
Maruf M. U. Ali et al.
EMBO JOURNAL (2011)
The eIF2 kinase PERK and the integrated stress response facilitate activation of ATF6 during endoplasmic reticulum stress
Brian F. Teske et al.
MOLECULAR BIOLOGY OF THE CELL (2011)
Pharmacologic Inhibition of ALK5 Causes Selective Induction of Terminal Differentiation in Mouse Keratinocytes Expressing Oncogenic HRAS
Lauren Mordasky Markell et al.
MOLECULAR CANCER RESEARCH (2011)
IRE1α controls cyclin A1 expression and promotes cell proliferation through XBP-1
Jeffery A. Thorpe et al.
CELL STRESS & CHAPERONES (2010)
The Crosstalk of RAS with the TGF-β Family During Carcinoma Progression and its Implications for Targeted Cancer Therapy
M. Grusch et al.
CURRENT CANCER DRUG TARGETS (2010)
TGFβ1-Induced Inflammation in Premalignant Epidermal Squamous Lesions Requires IL-17
Javed Mohammed et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2010)
A Crucial Role for RACK1 in the Regulation of Glucose-Stimulated IRE1α Activation in Pancreatic β Cells
Yifu Qiu et al.
SCIENCE SIGNALING (2010)
IRE1α Kinase Activation Modes Control Alternate Endoribonuclease Outputs to Determine Divergent Cell Fates
Dan Han et al.
CELL (2009)
Induction of p16ink4a and P19ARF by TGFβ1 Contributes to Growth Arrest and Senescence Response in Mouse Keratinocytes
Kinnimulki Vijayachandra et al.
MOLECULAR CARCINOGENESIS (2009)
Tumor Suppressor and Oncogene Actions of TGFβ1 Occur Early in Skin Carcinogenesis and Are Mediated by Smad3
Dong-Soon Bae et al.
MOLECULAR CARCINOGENESIS (2009)
Divergent Effects of PERK and IRE1 Signaling on Cell Viability
Jonathan H. Lin et al.
PLOS ONE (2009)
Isolation and short-term culture of primary keratinocytes, hair follicle populations and dermal cells from newborn mice and keratinocytes from adult mice for in vitro analysis and for grafting to immunodeficient mice
Ulrike Lichti et al.
NATURE PROTOCOLS (2008)
Many roads lead to oncogene-induced senescence
S. Courtois-Cox et al.
ONCOGENE (2008)
Smad3 deficiency inhibits v-ras-induced transformation by suppression of JNK MAPK signaling and increased farnesyl transferase inhibition
P. R. Arany et al.
ONCOGENE (2008)
Loss of TGFβ signaling destabilize homeostasis and promotes squalemous cell carcinomas in stratified epithelia
Geraldine Guasch et al.
CANCER CELL (2007)
Transcriptional induction of mammalian ER quality control proteins is mediated by single or combined action of ATF6α and XBP1
Keisuke Yamamoto et al.
DEVELOPMENTAL CELL (2007)
The ER chaperone and signaling regulator GRP78/BiP as a monitor of endoplasmic reticulum stress
AS Lee
METHODS (2005)
Survival and apoptosis signals in ER stress: the role of protein kinases
H Kadowaki et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2004)
XBP1, downstream of Blimp-1, expands the secretory apparatus and other organelles, and increases protein synthesis in plasma cell differentiation
AL Shaffer et al.
IMMUNITY (2004)
Protein-tyrosine phosphatase 1B potentiates IRE1 signaling during endoplasmic reticulum stress
[Anonymous]
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
XBP-1 regulates a subset of endoplasmic reticulum resident chaperone genes in the unfolded protein response
AH Lee et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
ER stress induces cleavage of membrane-bound ATF6 by the same proteases that process SREBPs
J Ye et al.
MOLECULAR CELL (2000)
PERK mediates cell-cycle exit during the mammalian unfolded protein response
JW Brewer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Oncogenic Ras-mediated cell growth arrest and apoptosis are associated with increased ubiquitin-dependent cyclin D1 degradation
JY Shao et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
A Bertolotti et al.
NATURE CELL BIOLOGY (2000)
Defects in TGFβ signaling overcome senescence of mouse keratinocytes expressing v-rasHa
R Tremain et al.
ONCOGENE (2000)
ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum
A Cabibbo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
Share Paper
