Do prodrome symptoms influence multiple sclerosis disease course and severity?

The recent studies in Multiple sclerosis field keep bringing up the current knowledge about MS prodrome period and its importance. Poorly studied and often underdiagnosed prodrome period can manifest in a variety of different symptoms affecting many organ systems. Based on literature findings regarding this topic, we suggest a hypothesis that some prodrome symptoms are seen more often in some courses of the MS. A careful and close investigation of the first symptoms which appear before the actual MS diagnosis could possibly help to predict the course and the severity of the disease and also be a forecast factor for future disability level. Acknowledging the significance of a MS prodrome period and new findings which could benefit both the physicians and the patients, we conducted a study in a local MS center in order to explore this hypothesis.

Automated summary

The recent studies in Multiple sclerosis field have highlighted the significance of the prodrome period in predicting the course and severity of the disease. However, this period is poorly studied and often overlooked. In order to explore this hypothesis, we conducted a study in a local MS center.