4.4 Editorial Material

Need for optimized dosages in the design of comparative clinical trials of anti-malarial drugs

Related references

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Article Infectious Diseases

Efficacy of 3-day low dose quinine plus clindamycin versus artemether-lumefantrine for the treatment of uncomplicated Plasmodium falciparum malaria in Kenyan children (CLINDAQUINE): an open-label randomized trial

Charles O. Obonyo et al.

Summary: This study found that a 3-day low dose course of quinine plus clindamycin is not effective in treating uncomplicated falciparum malaria in children under 5 years of age in Kenya, where artemether-lumefantrine remains effective.

MALARIA JOURNAL (2022)