4.2 Review

Synthetic PARP-1 Inhibitors Reported During the Last Decade

Related references

Note: Only part of the references are listed.
Article Chemistry, Medicinal

Design, synthesis and anticancer activities of novel dual poly(ADP-ribose) polymerase-1/histone deacetylase-1 inhibitors

Yongbin Tian et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2020)

Review Cell Biology

PARP and PARG inhibitors in cancer treatment

Dea Slade

GENES & DEVELOPMENT (2020)

Article Chemistry, Medicinal

Novel allosteric PARP1 inhibitors for the treatment of BRCA-deficient leukemia

Elizabeth Hewlett et al.

MEDICINAL CHEMISTRY RESEARCH (2020)

Article Chemistry, Medicinal

Design and synthesis of novel phthalazinone derivatives as potent poly(ADP-ribose)polymerase 1 inhibitors

Minhang Xin et al.

FUTURE MEDICINAL CHEMISTRY (2020)

Article Chemistry, Multidisciplinary

Design, synthesis and in silico studies of new quinazolinone derivatives as antitumor PARP-1 inhibitors

Sayed K. Ramadan et al.

RSC ADVANCES (2020)

Article Biochemistry & Molecular Biology

Design and synthesis of novel PARP-1 inhibitors based on pyridopyridazinone scaffold

Ghada F. Elmasry et al.

BIOORGANIC CHEMISTRY (2019)

Article Biochemistry & Molecular Biology

Design, synthesis and evaluation of phthalazinone thiohydantoin-based derivative as potent PARP-1 inhibitors

Yi Zhong et al.

BIOORGANIC CHEMISTRY (2019)

Article Chemistry, Multidisciplinary

Design, synthesis, biological evaluation and molecular docking of novel molecules to PARP-1 enzyme

Fatih Tok et al.

TURKISH JOURNAL OF CHEMISTRY (2019)

Article Chemistry, Medicinal

Design, synthesis and evaluation of potent and selective inhibitors of mono-(ADP-ribosyl)transferases PARP10 and PARP14

Jacob Holechek et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2018)

Article Chemistry, Organic

Synthesis of disaccharide nucleoside analogues as potential poly(ADP-ribose) polymerase-1 inhibitors

Meng Zheng et al.

ORGANIC & BIOMOLECULAR CHEMISTRY (2018)

Review Medicine, General & Internal

A review and update of vertebral fractures due to metastatic tumors of various sites to the spine: Percutaneous vertebroplasty

Mohamad Mansoorinasab et al.

INTERVENTIONAL MEDICINE AND APPLIED SCIENCE (2018)

Review Biochemistry & Molecular Biology

PARP1 in Carcinomas and PARP1 Inhibitors as Antineoplastic Drugs

Luyao Wang et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2017)

Article Biochemistry & Molecular Biology

Structure-based design of new poly (ADP-ribose) polymerase (PARP-1) inhibitors

Navriti Chadha et al.

MOLECULAR DIVERSITY (2017)

Review Cell Biology

The multifaceted roles of PARP1 in DNA repair and chromatin remodelling

Arnab Ray Chaudhuri et al.

NATURE REVIEWS MOLECULAR CELL BIOLOGY (2017)

Article Chemistry, Multidisciplinary

Novel Benzamide Derivatives: Synthesis and Bioactivity as Potent PARP-1 Inhibitors

Hwani Ryu et al.

BULLETIN OF THE KOREAN CHEMICAL SOCIETY (2017)

Article Biochemistry & Molecular Biology

Discovery of novel quinazoline-2,4(1H,3H)-dione derivatives as potent PARP-2 selective inhibitors

Hailong Zhao et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2017)

Article Chemistry, Medicinal

Design and synthesis of potent inhibitors of the mono(ADP-ribosyl) transferase, PARP14

Kristen Upton et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)

Article Biochemistry & Molecular Biology

Benzimidazole derivatives as potential dual inhibitors for PARP-1 and DHODH

Iskandar Abdullah et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2015)

Article Biochemistry & Molecular Biology

Discovery of 1-substituted benzyl-quinazoline-2,4(1H,3H)-dione derivatives as novel poly(ADP-ribose)polymerase-1 inhibitors

Haiping Yao et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2015)

Article Chemistry, Medicinal

Identification of novel PARP-1 inhibitors: Drug design, synthesis and biological evaluation

Zhouling Xie et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2015)

Article Biochemistry & Molecular Biology

7-Azaindole-1-carboxamides as a new class of PARP-1 inhibitors

Raffaella Cincinelli et al.

BIOORGANIC & MEDICINAL CHEMISTRY (2014)

Article Chemistry, Medicinal

Synthesis and biological evaluation of substituted 4-(thiophen-2-ylmethyl)-2H-phthalazin-1-ones as potent PARP-1 inhibitors

Ling-xiao Wang et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)

Article Chemistry, Medicinal

Synthesis of isoquinolinone-based tricycles as novel poly(ADP-ribose) polymerase-1 (PARP-1) inhibitors

Jianyang Chen et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)

Article Biotechnology & Applied Microbiology

Review of Poly (ADP-ribose) Polymerase (PARP) Mechanisms of Action and Rationale for Targeting in Cancer and Other Diseases

Julio C. Morales et al.

CRITICAL REVIEWS IN EUKARYOTIC GENE EXPRESSION (2014)

Article Chemistry, Medicinal

Discovery of novel benzo[b][1,4]oxazin-3(4H)-ones as poly(ADP-ribose)polymerase inhibitors

Anthony R. Gangloff et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)

Article Chemistry, Medicinal

Design, synthesis and biological evaluation of novel imidazo[4,5-c]pyridinecarboxamide derivatives as PARP-1 inhibitors

Qihua Zhu et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)

Article Chemistry, Medicinal

Synthesis and SAR optimization of quinazolin-4(3H)-ones as poly(ADP-ribose) polymerase-1 inhibitors

Shridhar S. Kulkarni et al.

EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2012)

Article

PARP inhibitors: its role in treatment of cancer

Alice Chen

Chinese Journal of Cancer (2011)