4.7 Article

A fetal fraction enrichment method reduces false negatives and increases test success rate of fetal chromosome aneuploidy detection in early pregnancy loss

Related references

Note: Only part of the references are listed.
Article Genetics & Heredity

High-throughput fetal fraction amplification increases analytical performance of noninvasive prenatal screening

Noah C. Welker et al.

Summary: A scalable fetal fraction amplification (FFA) technology was validated to increase FF in low-FF samples, improving the sensitivity and specificity of NIPS. Combining FFA with WGS-based NIPS can provide confident screening results for nearly all women.

GENETICS IN MEDICINE (2021)

Article Genetics & Heredity

Economic impact of using maternal plasma cell-free DNA testing to guide further workup in recurrent pregnancy loss

Siyang Peng et al.

Summary: The study demonstrated that including cfDNA testing in RPL workup is a cost-effective approach, improving sample accessibility, reducing unnecessary further investigations, and overall cost savings.

PRENATAL DIAGNOSIS (2021)

Article Medicine, General & Internal

Cell-Free DNA in the Investigation of Miscarriage

Emily Colley et al.

JOURNAL OF CLINICAL MEDICINE (2020)

Article Obstetrics & Gynecology

Sequencing shorter cfDNA fragments improves the fetal DNA fraction in noninvasive prenatal testing

Longwei Qiao et al.

AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY (2019)

Review Obstetrics & Gynecology

Potential genetic causes of miscarriage in euploid pregnancies: a systematic review

Emily Colley et al.

HUMAN REPRODUCTION UPDATE (2019)

Article Genetics & Heredity

Genetic analysis of products of conception using a HLPA/SNP-array strategy

Jun Mao et al.

MOLECULAR CYTOGENETICS (2019)

Article Obstetrics & Gynecology

Use of Cell-Free DNA in the Investigation of Intrauterine Fetal Demise and Miscarriage

Cecily A. Clark-Ganheart et al.

OBSTETRICS AND GYNECOLOGY (2015)

Article Medicine, General & Internal

Non-invasive prenatal assessment of trisomy 21 by multiplexed maternal plasma DNA sequencing: large scale validity study

Rossa W. K. Chiu et al.

BMJ-BRITISH MEDICAL JOURNAL (2011)