4.7 Article

Thoracoabdominal Aortic Disease and Repair JACC Focus Seminar, Part 3

Journal

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
Volume 80, Issue 8, Pages 845-856

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.jacc.2021.05.056

Keywords

aortic aneurysm; dissection; endovascular; thoracoabdominal aneurysm

Funding

  1. Munk Chair in Advanced Therapeutics
  2. Antonio and Helga DeGasperis Chair in Clinical Trials and Outcomes Research at the University Health Network
  3. Cook Medical
  4. W.L. Gore
  5. G.E. Healthcare
  6. Cullen Foundation

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Thoracoabdominal aortic disease is a rare but life-threatening condition that requires expert multidisciplinary collaborative management. Both open repair and endovascular approaches are viable options for repair, but specialized expertise is necessary for successful outcomes.
Thoracoabdominal aortic disease is a rare but life-threatening condition that requires expert multidisciplinary collaborative management. Intervention is indicated in patients with symptomatic aneurysms or when an aneurysm reaches a certain threshold of diameter or rate of expansion. The strategies for spinal cord and end-organ protection have evolved over several decades, resulting in improved outcomes after repair. Open repair, although invasive, provides definitive and durable repair. Endovascular approaches are rapidly evolving, and the results with fenestrated and branched endografts are promising. Both open repair and endovascular repair require highly specialized expertise, and outcomes are best when repair is undertaken in an elective setting by a dedicated team. Patients with degenerative thoracoabdominal aortic aneurysms and chronic dissections should be followed up closely and referred for elective repair when indicated. (C) 2022 by the American College of Cardiology Foundation.

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