SYNTHESES, CRYSTAL STRUCTURES AND ANTIBACTERIAL ACTIVITIES OF MONONUCLEAR NICKEL(II) COMPLEXES WITH SIMILAR SCHIFF BASES

Two mononuclear nickel(II) complexes, [Ni(L-1)(2)] (1) and [Ni(L-2)(2)] (2), where L-1 and L-2 are the anions of 4-methylbenzoic acid (1-pyridin-2-ylmethylidene)hydrazide (HL1) and benzoic acid (1-pyridine-2-ylethylidene)hydrazide (HL2), respectively, were prepared and characterized by physico-chemical methods and single crystal X-ray diffraction. The tridentate Schiff base ligands coordinate to the Ni atoms through the pyridine nitrogen, imino nitrogen and enolate oxygen atoms. The Ni atom in each complex is six coordinated by two Schiff base ligands, to form octahedral coordination. To investigate the influence of the position of methyl group on the antibacterial activities, the complexes have been studied on the bacteria Bacillus subtilis, Staphylococcus aureus, Escherichia coli and Pseudomonas fluorescens.

Automated summary

In this study, two mononuclear nickel(II) complexes were synthesized and characterized by physico-chemical methods and single crystal X-ray diffraction. The influence of the position of methyl group on the antibacterial activities of these complexes was investigated through studies on different bacteria.